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Multi-modal Large Language Models (MLLMs) are increasingly prominent in the field of artificial intelligence. Visual instruction fine-tuning (IFT) is a vital process for aligning MLLMs' output with user's intentions. High-quality and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xiaotian Han , Yiqi Wang , Bohan Zhai , Quanzeng You , Hongxia Yang

Pre-trained language models for code (PLMCs) have gained attention in recent research. These models are pre-trained on large-scale datasets using multi-modal objectives. However, fine-tuning them requires extensive supervision and is…

Computation and Language · Computer Science 2023-05-11 Hung Quoc To , Nghi D. Q. Bui , Jin Guo , Tien N. Nguyen

The rapid integration of Large Language Models (LLMs) into various industries presents both revolutionary opportunities and unique challenges. This research aims to establish a scalable and efficient framework for LLM customization,…

Software Engineering · Computer Science 2024-05-22 Panos Fitsilis , Vyron Damasiotis , Vasileios Kyriatzis , Paraskevi Tsoutsa

Large Language Models (LLMs) have shown remarkable success, and their multimodal expansions (MLLMs) further unlock capabilities spanning images, videos, and other modalities beyond text. However, despite this shift, prompt optimization…

Machine Learning · Computer Science 2026-02-20 Yumin Choi , Dongki Kim , Jinheon Baek , Sung Ju Hwang

Molecular representation learning is pivotal for various molecular property prediction tasks related to drug discovery. Robust and accurate benchmarks are essential for refining and validating current methods. Existing molecular property…

Chemical Physics · Physics 2024-06-27 Shikun Feng , Jiaxin Zheng , Yinjun Jia , Yanwen Huang , Fengfeng Zhou , Wei-Ying Ma , Yanyan Lan

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Khiem Le , Zhichun Guo , Kaiwen Dong , Xiaobao Huang , Bozhao Nan , Roshni Iyer , Xiangliang Zhang , Olaf Wiest , Wei Wang , Ting Hua , Nitesh V. Chawla

Large Language Models (LLMs) have revolutionized various domains but encounter substantial challenges in tackling optimization modeling tasks for Operations Research (OR), particularly when dealing with complex problem. In this work, we…

Computation and Language · Computer Science 2025-06-24 Yang Wu , Yifan Zhang , Yurong Wu , Yuran Wang , Junkai Zhang , Jian Cheng

Although multimodal large language models (MLLMs) excel in high-level vision-language reasoning, they lack inherent awareness of visual saliency, making it difficult to identify key visual elements. To bridge this gap, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Long Li , Shuichen Ji , Ziyang Luo , Zhihui Li , Dingwen Zhang , Junwei Han , Nian Liu

Large Language Models (LLMs) have demonstrated significant potential in transforming clinical applications. In this study, we investigate the efficacy of four techniques in adapting LLMs for clinical use-cases: continuous pretraining,…

Molecular property prediction is an increasingly critical task within drug discovery and development. Typically, neural networks can learn molecular properties using graph-based, language-based or feature-based methods. Recent advances in…

Machine Learning · Computer Science 2025-07-31 Philip Spence , Brooks Paige , Anne Osbourn

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Multimodal Large Language Models (MLLMs) inherit the superior text understanding capabilities of LLMs and extend these capabilities to multimodal scenarios. These models achieve excellent results in the general domain of multimodal tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jinlong He , Pengfei Li , Gang Liu , Shenjun Zhong

Instruction tuning is a burgeoning method to elicit the general intelligence of Large Language Models (LLMs). While numerous studies have examined the impact of factors such as data volume and model size on English models, the scaling…

Computation and Language · Computer Science 2025-03-04 Chiyu Song , Zhanchao Zhou , Jianhao Yan , Yuejiao Fei , Zhenzhong Lan , Yue Zhang

The application of Large Language Models (LLMs) in Computer-Aided Design (CAD) remains an underexplored area, despite their remarkable advancements in other domains. In this paper, we present BlenderLLM, a novel framework for training LLMs…

Human-Computer Interaction · Computer Science 2024-12-20 Yuhao Du , Shunian Chen , Wenbo Zan , Peizhao Li , Mingxuan Wang , Dingjie Song , Bo Li , Yan Hu , Benyou Wang

Large Language Models (LLMs) have demonstrated remarkable abilities in general scenarios. Instruction finetuning empowers them to align with humans in various tasks. Nevertheless, the Diversity and Quality of the instruction data remain two…

Computation and Language · Computer Science 2024-07-09 Xingyuan Pan , Luyang Huang , Liyan Kang , Zhicheng Liu , Yu Lu , Shanbo Cheng

In the past year, MultiModal Large Language Models (MM-LLMs) have undergone substantial advancements, augmenting off-the-shelf LLMs to support MM inputs or outputs via cost-effective training strategies. The resulting models not only…

Computation and Language · Computer Science 2024-05-29 Duzhen Zhang , Yahan Yu , Jiahua Dong , Chenxing Li , Dan Su , Chenhui Chu , Dong Yu

As large language models (LLMs) see greater use in academic and commercial settings, there is increasing interest in methods that allow language models to generate texts aligned with human preferences. In this paper, we present an initial…

Machine Learning · Computer Science 2024-06-07 Victoria Lin , Eli Ben-Michael , Louis-Philippe Morency

Multi-modal large language models (MLLMs) have achieved remarkable success on complex multi-modal tasks. However, it remains insufficiently explored whether they exhibit $\textbf{modality preference}$, a tendency to favor one modality over…

Computation and Language · Computer Science 2026-02-05 Yu Zhang , Jinlong Ma , Yongshuai Hou , Xuefeng Bai , Kehai Chen , Yang Xiang , Jun Yu , Min Zhang

Solving multimodal optimization problems (MMOP) requires finding all optimal solutions, which is challenging in limited function evaluations. Although existing works strike the balance of exploration and exploitation through hand-crafted…

Neural and Evolutionary Computing · Computer Science 2024-04-15 Hongqiao Lian , Zeyuan Ma , Hongshu Guo , Ting Huang , Yue-Jiao Gong

Large language models (LLMs) hold transformative potential for medical decision support yet their application in psychiatry remains constrained by hallucinations and superficial reasoning. This limitation is particularly acute in…

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