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Dementia affects cognitive functions of adults, including memory, language, and behaviour. Standard diagnostic biomarkers such as MRI are costly, whilst neuropsychological tests suffer from sensitivity issues in detecting dementia onset.…

Computation and Language · Computer Science 2023-12-27 Dimitris Gkoumas , Bo Wang , Adam Tsakalidis , Maria Wolters , Arkaitz Zubiaga , Matthew Purver , Maria Liakata

Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

Computation and Language · Computer Science 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

We introduce initial groundwork for estimating suicide risk and mental health in a deep learning framework. By modeling multiple conditions, the system learns to make predictions about suicide risk and mental health at a low false positive…

Computation and Language · Computer Science 2017-12-12 Adrian Benton , Margaret Mitchell , Dirk Hovy

Depression is a major global public health challenge and its early identification is crucial. Social media data provides a new perspective for depression detection, but existing methods face limitations such as insufficient accuracy,…

Artificial Intelligence · Computer Science 2026-01-12 Yukun Yang

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Early identification of stroke symptoms is essential for enabling timely intervention and improving patient outcomes, particularly in prehospital settings. This study presents a fast, non-invasive multimodal deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Ngoc-Khai Hoang , Thi-Nhu-Mai Nguyen , Huy-Hieu Pham

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

The significance of mental health classification is paramount in contemporary society, where digital platforms serve as crucial sources for monitoring individuals' well-being. However, existing social media mental health datasets primarily…

Computation and Language · Computer Science 2024-11-08 Rina Carines Cabral , Siwen Luo , Josiah Poon , Soyeon Caren Han

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

Sound · Computer Science 2026-05-26 Loukas Ilias , Dimitris Askounis

Early identification of suicide risk is crucial for preventing suicidal behaviors. As a result, the identification and study of patterns and markers related to suicide risk have become a key focus of current research. In this paper, we…

Sound · Computer Science 2025-07-02 Yifan Gao , Jiao Fu , Long Guo , Hong Liu

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

This paper presents our solution to the Multimodal Personality-aware Depression Detection (MPDD) challenge at ACM MM 2025. We propose a multimodal depression detection model in the Elderly that incorporates personality characteristics. We…

Sound · Computer Science 2025-10-10 Honghong Wang , Jing Deng , Rong Zheng

Speech-based depression detection has shown promise as an objective diagnostic tool, yet the cross-linguistic robustness of acoustic markers and their neurobiological underpinnings remain underexplored. This study extends Cross-Data…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Fuxiang Tao , Dongwei Li , Shuning Tang , Xuri Ge , Wei Ma , Anna Esposito , Alessandro Vinciarelli

Major Depressive Disorder (MDD) is a common worldwide mental health issue with high associated socioeconomic costs. The prediction and automatic detection of MDD can, therefore, make a huge impact on society. Speech, as a non-invasive, easy…

Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jiuyi Chen , Mingkui Tan , Haifeng Lu , Qiuna Xu , Zhihua Wang , Runhao Zeng , Xiping Hu

Multimodal depression classification has gained immense popularity over the recent years. We develop a multimodal depression classification system using articulatory coordination features extracted from vocal tract variables and text…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-15 Nadee Seneviratne , Carol Espy-Wilson

We propose a novel explainable machine learning (ML) model that identifies depression from speech, by modeling the temporal dependencies across utterances and utilizing the spectrotemporal information at the vowel level. Our method first…

Sound · Computer Science 2022-10-28 Kexin Feng , Theodora Chaspari

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

Artificial Intelligence · Computer Science 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen