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Inference after model selection has been an active research topic in the past few years, with numerous works offering different approaches to addressing the perils of the reuse of data. In particular, major progress has been made recently…

Methodology · Statistics 2020-06-02 Snigdha Panigrahi , Jonathan Taylor , Asaf Weinstein

We show that model compression can improve the population risk of a pre-trained model, by studying the tradeoff between the decrease in the generalization error and the increase in the empirical risk with model compression. We first prove…

Machine Learning · Statistics 2019-01-29 Yuheng Bu , Weihao Gao , Shaofeng Zou , Venugopal V. Veeravalli

When the body gets infected by a pathogen or receives a vaccine dose, the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery/vaccination the host might become susceptible again.…

Populations and Evolution · Quantitative Biology 2015-01-15 Maria Vittoria Barbarossa , Gergely Röst

Modern machine learning pipelines leverage large amounts of public data, making it infeasible to guarantee data quality and leaving models open to poisoning and backdoor attacks. Provably bounding model behavior under such attacks remains…

Machine Learning · Computer Science 2024-10-31 Philip Sosnin , Mark N. Müller , Maximilian Baader , Calvin Tsay , Matthew Wicker

There is a growing need for investigating how machine learning models operate. With this work, we aim to understand trained machine learning models by questioning their data preferences. We propose a mathematical framework that allows us to…

Machine Learning · Computer Science 2025-12-22 Eren Mehmet Kıral , Nurşen Aydın , Ş. İlker Birbil

Language model finetuning often results in learning undesirable traits in combination with desired ones. To address this, we propose inoculation prompting: modifying finetuning data by prepending a short system-prompt instruction that…

Computation and Language · Computer Science 2025-11-04 Daniel Tan , Anders Woodruff , Niels Warncke , Arun Jose , Maxime Riché , David Demitri Africa , Mia Taylor

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

Language models (LMs) are pretrained to imitate internet text, including content that would violate human preferences if generated by an LM: falsehoods, offensive comments, personally identifiable information, low-quality or buggy code, and…

Computation and Language · Computer Science 2023-06-16 Tomasz Korbak , Kejian Shi , Angelica Chen , Rasika Bhalerao , Christopher L. Buckley , Jason Phang , Samuel R. Bowman , Ethan Perez

Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Fuping Wu , Bartlomiej W. Papiez

This paper presents a general framework for estimating high-dimensional conditional latent factor models via constrained nuclear norm regularization. We establish large sample properties of the estimators and provide efficient algorithms…

Econometrics · Economics 2025-12-09 Qihui Chen

Denoising diffusion models have gained popularity as a generative modeling technique for producing high-quality and diverse images. Applying these models to downstream tasks requires conditioning, which can take the form of text, class…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

The purpose of time series analysis via mechanistic models is to reconcile the known or hypothesized structure of a dynamical system with observations collected over time. We develop a framework for constructing nonlinear mechanistic models…

Statistics Theory · Mathematics 2009-06-08 Carles Bretó , Daihai He , Edward L. Ionides , Aaron A. King

Mislabeled, duplicated, or biased data in real-world scenarios can lead to prolonged training and even hinder model convergence. Traditional solutions prioritizing easy or hard samples lack the flexibility to handle such a variety…

Machine Learning · Computer Science 2023-11-08 Zhijie Deng , Peng Cui , Jun Zhu

Language models trained on large-scale unfiltered datasets curated from the open web acquire systemic biases, prejudices, and harmful views from their training data. We present a methodology for programmatically identifying and removing…

Computation and Language · Computer Science 2021-11-30 Helen Ngo , Cooper Raterink , João G. M. Araújo , Ivan Zhang , Carol Chen , Adrien Morisot , Nicholas Frosst

Our intention is to provide a definitive reference on what it would take to safely make use of generative/predictive models in the absence of a solution to the Eliciting Latent Knowledge problem. Furthermore, we believe that large language…

Artificial Intelligence · Computer Science 2023-02-07 Evan Hubinger , Adam Jermyn , Johannes Treutlein , Rubi Hudson , Kate Woolverton

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Neural networks are among the most accurate supervised learning methods in use today. However, their opacity makes them difficult to trust in critical applications, especially when conditions in training may differ from those in practice.…

Machine Learning · Computer Science 2018-10-03 Andrew Slavin Ross

Deep learning models have proven to be exceptionally useful in performing many machine learning tasks. However, for each new dataset, choosing an effective size and structure of the model can be a time-consuming process of trial and error.…

Machine Learning · Computer Science 2019-08-08 Roozbeh Yousefzadeh , Dianne P O'Leary

Antibody therapies have been employed to address some of today's most challenging diseases, but must meet many criteria during drug development before reaching a patient. Humanization is a sequence optimization strategy that addresses one…

Machine Learning · Computer Science 2024-12-10 Cade Gordon , Aniruddh Raghu , Peyton Greenside , Hunter Elliott

In this study, an efficient method to immunize modular networks (i.e., networks with community structure) is proposed. The immunization of networks aims at fragmenting networks into small parts with a small number of removed nodes. Its…

Populations and Evolution · Quantitative Biology 2010-03-24 Naoki Masuda