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Reasoning is a hallmark of human intelligence, enabling adaptive decision-making in complex and unfamiliar scenarios. In contrast, machine intelligence remains bound to training data, lacking the ability to dynamically refine solutions at…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Shaheer U. Saeed , Yipei Wang , Veeru Kasivisvanathan , Brian R. Davidson , Matthew J. Clarkson , Yipeng Hu , Daniel C. Alexander

Artificial intelligence (AI), particularly machine learning and deep learning models, has significantly impacted bioinformatics research by offering powerful tools for analyzing complex biological data. However, the lack of interpretability…

Artificial Intelligence · Computer Science 2023-12-12 Zhongliang Zhou , Mengxuan Hu , Mariah Salcedo , Nathan Gravel , Wayland Yeung , Aarya Venkat , Dongliang Guo , Jielu Zhang , Natarajan Kannan , Sheng Li

Large Language Models (LLMs) have shown remarkable reasoning capabilities, while their practical applications are limited by severe factual hallucinations due to limitations in the timeliness, accuracy, and comprehensiveness of their…

Artificial Intelligence · Computer Science 2025-06-10 Xinyan Guan , Jiali Zeng , Fandong Meng , Chunlei Xin , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Jie Zhou

In high-stakes domains such as healthcare and finance, effective decision-making demands not just accurate outcomes but transparent and explainable reasoning. However, current language models often lack the structured deliberation needed…

Computation and Language · Computer Science 2025-08-26 Xiusi Chen , Shanyong Wang , Cheng Qian , Hongru Wang , Peixuan Han , Heng Ji

Language has long been conceived as an essential tool for human reasoning. The breakthrough of Large Language Models (LLMs) has sparked significant research interest in leveraging these models to tackle complex reasoning tasks. Researchers…

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…

Machine Learning · Computer Science 2025-05-27 Andrew Zamai , Nathanael Fijalkow , Boris Mansencal , Laurent Simon , Eloi Navet , Pierrick Coupe

Biomedical text mining and question-answering are essential yet highly demanding tasks, particularly in the face of the exponential growth of biomedical literature. In this work, we present our participation in the 13th edition of the…

Computation and Language · Computer Science 2025-08-05 Dimitra Panou , Alexandros C. Dimopoulos , Manolis Koubarakis , Martin Reczko

Interpretable machine learning aims to provide transparent models whose decision-making processes can be readily understood by humans. Recent advances in rule-based approaches, such as expressive Boolean formulas (BoolXAI), offer faithful…

Artificial Intelligence · Computer Science 2026-05-13 Du Cheng , Serdar Kadioglu , Xin Wang

Large Language Models (LLMs) have shown impressive performance across various domains, but their ability to perform molecular reasoning remains underexplored. Existing methods mostly rely on general-purpose prompting, which lacks…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Objective: Most existing fine-tuned biomedical large language models (LLMs) focus on enhancing performance in monolingual biomedical question answering and conversation tasks. To investigate the effectiveness of the fine-tuned LLMs on…

Strong Artificial Intelligence (Strong AI) or Artificial General Intelligence (AGI) with abstract reasoning ability is the goal of next-generation AI. Recent advancements in Large Language Models (LLMs), along with the emerging field of…

Computation and Language · Computer Science 2024-01-19 Yiqi Wang , Wentao Chen , Xiaotian Han , Xudong Lin , Haiteng Zhao , Yongfei Liu , Bohan Zhai , Jianbo Yuan , Quanzeng You , Hongxia Yang

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Living organisms survive and multiply even though they have uncertain and incomplete information about their environment and imperfect models to predict the consequences of their actions. Bayesian models have been proposed to face this…

Emerging Technologies · Computer Science 2015-11-13 Jacques Droulez , David Colliaux , Audrey Houillon , Pierre Bessière

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Machine learning is a modern approach to problem-solving and task automation. In particular, machine learning is concerned with the development and applications of algorithms that can recognize patterns in data and use them for predictive…

Modern life sciences research is increasingly relying on artificial intelligence approaches to model biological systems, primarily centered around the use of machine learning (ML) models. Although ML is undeniably useful for identifying…

Computational argumentation offers formal frameworks for transparent, verifiable reasoning but has traditionally been limited by its reliance on domain-specific information and extensive feature engineering. In contrast, LLMs excel at…

Artificial Intelligence · Computer Science 2026-03-18 Stylianos Loukas Vasileiou , Antonio Rago , Francesca Toni , William Yeoh

Large Language Models (LLMs) have shown human-like reasoning abilities but still face challenges in solving complex logical problems. Existing unidirectional chaining methods, such as forward chaining and backward chaining, suffer from…

Computation and Language · Computer Science 2024-06-12 Shuqi Liu , Bowei He , Linqi Song