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Related papers: BioReason: Incentivizing Multimodal Biological Rea…

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Recent advancements in Large Language Models (LLMs) have demonstrated remarkable capabilities in various domains. However, effective decision-making relies heavily on strong reasoning abilities. Reasoning is the foundation for…

Computation and Language · Computer Science 2025-06-30 Dana Alsagheer , Yang Lu , Abdulrahman Kamal , Omar Kamal , Mohammad Kamal , Nada Mansour , Cosmo Yang Wu , Rambiba Karanjai , Sen Li , Weidong Shi

Large Language Models (LLMs) have demonstrated impressive capability in many natural language tasks. However, the auto-regressive generation process makes LLMs prone to produce errors, hallucinations and inconsistent statements when…

Artificial Intelligence · Computer Science 2024-07-23 Chaojie Wang , Yanchen Deng , Zhiyi Lyu , Liang Zeng , Jujie He , Shuicheng Yan , Bo An

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Large language models (LLMs) have shown remarkable capabilities in general domains, but their application to multi-omics biology remains underexplored. To address this gap, we introduce Biology-Instructions, the first large-scale…

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

Human-Computer Interaction · Computer Science 2025-03-03 Siting Liang , Daniel Sonntag

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Recent advances in Vision Language Models (VLMs) have driven significant progress in visual reasoning. However, open-source VLMs still lag behind proprietary systems, largely due to the lack of high-quality reasoning data. Existing datasets…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Honglin Lin , Zheng Liu , Yun Zhu , Chonghan Qin , Juekai Lin , Xiaoran Shang , Conghui He , Wentao Zhang , Lijun Wu

Achieving human-level intelligence requires refining the transition from the fast, intuitive System 1 to the slower, more deliberate System 2 reasoning. While System 1 excels in quick, heuristic decisions, System 2 relies on logical…

Reasoning lies at the heart of intelligence, shaping the ability to make decisions, draw conclusions, and generalize across domains. In artificial intelligence, as systems increasingly operate in open, uncertain, and multimodal…

Despite the large corpus of biology training text, the impact of reasoning models on biological research generally lags behind math and coding. In this work, we show that biology questions from current large-scale reasoning datasets do not…

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Computation and Language · Computer Science 2024-05-13 Taeyoon Kwon , Kai Tzu-iunn Ong , Dongjin Kang , Seungjun Moon , Jeong Ryong Lee , Dosik Hwang , Yongsik Sim , Beomseok Sohn , Dongha Lee , Jinyoung Yeo

This paper surveys foundation models for AI-enabled biological design, focusing on recent developments in applying large-scale, self-supervised models to tasks such as protein engineering, small molecule design, and genomic sequence design.…

Artificial Intelligence · Computer Science 2025-05-20 Asher Moldwin , Amarda Shehu

Neuro-symbolic AI systems integrate neural perception with symbolic reasoning to enable data-efficient, interpretable, and robust intelligence beyond purely neural models. Although this compositional paradigm has shown superior performance…

Artificial Intelligence · Computer Science 2026-01-29 Zishen Wan , Che-Kai Liu , Jiayi Qian , Hanchen Yang , Arijit Raychowdhury , Tushar Krishna

Large Language Models (LLMs) struggle with accuracy, domain-specific reasoning, and interpretability in vertical domains. Traditional preference alignment methods like Reinforcement Learning from Human Feedback (RLHF) and Direct Preference…

Computation and Language · Computer Science 2025-06-04 Qihang Yan , Xinyu Zhang , Luming Guo , Qi Zhang , Feifan Liu

We investigate how to teach large language models (LLMs) to perform scientific reasoning by leveraging expert discussions as a learning signal. Focusing on the genomics domain, we develop an automated pipeline to extract trainable data and…

Artificial Intelligence · Computer Science 2025-06-04 Ming Yin , Yuanhao Qu , Ling Yang , Le Cong , Mengdi Wang

Conventional biomedical research is increasingly labor-intensive due to the exponential growth of scientific literature and datasets. Artificial intelligence (AI), particularly Large Language Models (LLMs), has the potential to…

Multiagent Systems · Computer Science 2025-07-08 Yi Luo , Linghang Shi , Yihao Li , Aobo Zhuang , Yeyun Gong , Ling Liu , Chen Lin

Large Language Models (LLMs) are being integrated into professional domains, yet their limitations in such high-stakes fields as law remain poorly understood. In response, this paper introduces examples of critical challenges to the…

Artificial Intelligence · Computer Science 2026-01-27 Eljas Linna , Tuula Linna

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Although contemporary large language models (LMs) demonstrate impressive question-answering capabilities, their answers are typically the product of a single call to the model. This entails an unwelcome degree of opacity and compromises…

Artificial Intelligence · Computer Science 2022-08-31 Antonia Creswell , Murray Shanahan

Large Language Models (LLMs) have rapidly transformed the landscape of artificial intelligence, enabling natural language interfaces and dynamic orchestration of software components. However, their reliance on probabilistic inference limits…

Machine Learning · Computer Science 2025-07-01 Claudionor Coelho , Yanen Li , Philip Tee