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Sepsis is a dangerous condition that is a leading cause of patient mortality. Treating sepsis is highly challenging, because individual patients respond very differently to medical interventions and there is no universally agreed-upon…

Machine Learning · Computer Science 2018-11-28 Aniruddh Raghu , Matthieu Komorowski , Sumeetpal Singh

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

This demo presents SeizNet, an innovative system for predicting epileptic seizures benefiting from a multi-modal sensor network and utilizing Deep Learning (DL) techniques. Epilepsy affects approximately 65 million people worldwide, many of…

Objectives: To evaluate the consequences of the framing of machine learning risk prediction models. We evaluate how framing affects model performance and model learning in four different approaches previously applied in published…

Sepsis remains a critical challenge due to its high mortality and complex prognosis. To address data limitations in studying MSSA sepsis, we extend existing transfer learning frameworks to accommodate transformation models for…

Applications · Statistics 2025-04-16 Nan Qiao , Haowei Jiang , Cunjie Lin

Timely and interpretable early warning of sepsis remains a major clinical challenge due to the complex temporal dynamics of physiological deterioration. Traditional data-driven models often provide accurate yet opaque predictions, limiting…

Machine Learning · Computer Science 2026-04-24 Weizhi Nie , Zhen Qu , Weijie Wang , Chunpei Li , Ke Lu , Bingyang Zhou , Hongzhi Yu

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

As advancements in technology and medicine are being made, many countries are still unable to access quality medical care due to cost and lack of qualified medical personnel. This discrepancy in healthcare has caused many preventable…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Kyler Larsen

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

Computation and Language · Computer Science 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

An accurate seizure prediction system enables early warnings before seizure onset of epileptic patients. It is extremely important for drug-refractory patients. Conventional seizure prediction works usually rely on features extracted from…

Signal Processing · Electrical Eng. & Systems 2021-08-18 Yankun Xu , Jie Yang , Shiqi Zhao , Hemmings Wu , Mohamad Sawan

Sepsis is a life-threatening condition affecting one million people per year in the US in which dysregulation of the body's own immune system causes damage to its tissues, resulting in a 28 - 50% mortality rate. Clinical trials for sepsis…

Machine Learning · Computer Science 2018-03-01 Brenden K. Petersen , Jiachen Yang , Will S. Grathwohl , Chase Cockrell , Claudio Santiago , Gary An , Daniel M. Faissol

Although there has been significant research in boosting of weak learners, there has been little work in the field of boosting from strong learners. This latter paradigm is a form of weighted voting with learned weights. In this work, we…

Machine Learning · Computer Science 2020-12-22 Matthew A. Reyna , Gari D. Clifford

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…

Signal Processing · Electrical Eng. & Systems 2025-01-29 Mathan Kumar Mounagurusamy , Thiyagarajan V S , Abdur Rahman , Shravan Chandak , D. Balaji , Venkateswara Rao Jallepalli

Epilepsy is a chronic neurological condition characterized by recurrent seizures, with global prevalence estimated at 50 million people worldwide. While progress in high-throughput sequencing has allowed for broad-based transcriptomic…

Genomics · Quantitative Biology 2025-10-02 Muhammad Omer Latif , Hayat Ullah , Muhammad Ali Shafique , Zhihua Dong

Sepsis is a life-threatening syndrome with high morbidity and mortality in hospitals. Early prediction of sepsis plays a crucial role in facilitating early interventions for septic patients. However, early sepsis prediction systems with…

Machine Learning · Computer Science 2025-03-20 Anni Zhou , Beyah Raheem , Rishikesan Kamaleswaran , Yao Xie

Sepsis is a severe medical condition caused by a dysregulated host response to infection that has a high incidence and mortality rate. Even with such a high-level occurrence rate, the detection and diagnosis of sepsis continues to pose a…

Applications · Statistics 2022-10-27 Jeffrey R. Smith , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

The acute respiratory distress syndrome (ARDS) is a severe form of hypoxemic respiratory failure with in-hospital mortality of 35-46%. High mortality is thought to be related in part to challenges in making a prompt diagnosis, which may in…

Machine Learning · Computer Science 2021-09-28 Gregory B. Rehm , Chao Wang , Irene Cortes-Puch , Chen-Nee Chuah , Jason Adams

Spiking neural network (SNN) is a biologically-plausible model and exhibits advantages of high computational capability and low power consumption. While the training of deep SNN is still an open problem, which limits the real-world…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Shuiying Xiang , Tao Zhang , Shuqing Jiang , Yanan Han , Yahui Zhang , Chenyang Du , Xingxing Guo , Licun Yu , Yuechun Shi , Yue Hao

Epilepsy is a neurological brain disorder which life threatening and gives rise to recurrent seizures that are unprovoked. It occurs due to the abnormal chemical changes in our brain. Over the course of many years, studies have been…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Muhammad Shoaib Farooq , Aimen Zulfiqar , Shamyla Riaz