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Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has…

A combination of traditional image processing methods with advanced neural networks concretes a predictive and preventive healthcare paradigm. This study offers rapid, accurate, and non-invasive diagnostic solutions that can significantly…

The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muntasir Mamun , Md Ishtyaq Mahmud , Mahabuba Meherin , Ahmed Abdelgawad

Motivation. Understanding the pan-cancer mutational landscape offers critical insights into the molecular mechanisms underlying tumorigenesis. While patient-level machine learning techniques have been widely employed to identify tumor…

Machine Learning · Computer Science 2025-08-29 Yifan Dou , Adam Khadre , Ruben C Petreaca , Golrokh Mirzaei

Accurate identification of EGFR and KRAS mutations is essential for precision therapy in non-small cell lung cancer (NSCLC), but tissue genotyping is invasive and may not capture tumor heterogeneity. CT-based radiogenomics offers a…

Smoking continues to be a major preventable cause of death worldwide, affecting millions through damage to the heart, metabolism, liver, and kidneys. However, current medical screening methods often miss the early warning signs of…

Machine Learning · Computer Science 2026-01-27 Vaskar Chakma , MD Jaheid Hasan Nerab , Abdur Rouf , Abu Sayed , Hossem MD Saim , Md. Nournabi Khan

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Colon cancer is the second leading cause of cancer-related death in the United States of America. Its prognosis has significantly improved with the advancement of targeted therapies based on underlying molecular changes. The KRAS mutation…

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

Lung cancer remains the leading cause of cancer mortality, driving the development of automated screening tools to alleviate radiologist workload. Standing at the frontier of this effort is Sybil, a deep learning model capable of predicting…

The CyberKnife system is a robotic radiosurgery platform that allows the delivery of lung SBRT treatments using fiducial-free soft-tissue tracking. However, not all lung cancer patients are eligible for lung tumor tracking. Tumor size,…

Medical Physics · Physics 2023-08-24 Matthieu Lafrenière , Gilmer Valdes , Martina Descovich

Background: CT imaging is vital for lung cancer management, offering detailed visualization for AI-based prognosis. However, supervised learning SL models require large labeled datasets, limiting their real-world application in settings…

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer CT screening has been shown to reduce mortality by up to 40% and is now included in US screening guidelines.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Daniel Korat

Since, cancer is curable when diagnosed at an early stage, lung cancer screening plays an important role in preventive care. Although both low dose computed tomography (LDCT) and computed tomography (CT) scans provide more medical…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Worawate Ausawalaithong , Sanparith Marukatat , Arjaree Thirach , Theerawit Wilaiprasitporn

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Jinqiu Chen , Huyan Xu

Multimodal Machine Learning offers a holistic view of a patient's status, integrating structured and unstructured data from electronic health records (EHR). We propose a framework to predict metastasis risk one month prior to diagnosis,…

Machine Learning · Computer Science 2026-04-01 Franco Rugolon , Korbinian Randl , Braslav Jovanovic , Ioanna Miliou , Panagiotis Papapetrou

Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Pouya Afshin , David Helminiak , Tianling Niu , Julie M. Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

The purpose of this study is to develop a computer-aided diagnosis system for classifying benign and malignant lung lesions, and to assist physicians in real-time analysis of radial probe endobronchial ultrasound (EBUS) videos. During the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Ching-Kai Lin , Chin-Wen Chen , Yun-Chien Cheng

Accurately predicting gene mutations, mutation subtypes and their exons in lung cancer is critical for personalized treatment planning and prognostic assessment. Faced with regional disparities in medical resources and the high cost of…

Genomics · Quantitative Biology 2025-12-01 Liangrui Pan , Qingchun Liang , Shen Zhao , Songqing Fan , Shaoliang Peng