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We have studied by Molecular Dynamics computer simulations the dynamics of water confined in ionic surfactants phases, ranging from well ordered lamellar structures to micelles at low and high water loading, respectively. We have analysed…

Soft Condensed Matter · Physics 2016-03-23 Samuel Hanot , Sandrine Lyonnard , Stefano Mossa

Plasma membranes appear as deformable systems wherein molecules are free to move and diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane proteins and cholesterol) surrounded by disordered lipid…

Soft Condensed Matter · Physics 2024-09-25 Chiara Bernard , Angelo Rosario Carotenuto , Nicola Maria Pugno , Luca Deseri , Massimiliano Fraldi

The mathematical, four-layer model of the LDL transport across the arterial wall including the sensitivity of the transport coefficients to the wall shear stress (WSS) is studied. In that model the advection-diffusion equations in porous…

Tissues and Organs · Quantitative Biology 2014-09-03 Katarzyna Jesionek , Marcin Kostur

Soft colloids allow to explore high density states well beyond random close packing. An important open question is whether softness controls the dynamics under these dense conditions. While experimental works reported conflicting results,…

Soft Condensed Matter · Physics 2021-06-08 Nicoletta Gnan , Emanuela Zaccarelli

Collective motion is often modeled within the framework of active fluids, where the constituent active particles, when interactions with other particles are switched off, perform normal diffusion at long times. However, in biology,…

Statistical Mechanics · Physics 2020-04-02 Andrea Cairoli , Chiu Fan Lee

By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon…

Soft Condensed Matter · Physics 2018-07-04 Martin Vögele , Jürgen Köfinger , Gerhard Hummer

Lubricated contacts in soft materials are important in various engineering systems and natural settings. Three major lubrication regimes are boundary (BL), mixed (ML), and elasto-hydrodynamic (EHL) lubrication, where the contact region is…

Soft Condensed Matter · Physics 2024-12-17 Hao Dong , Reshma Siddiquie , Xuemei Xiao , Michael Andrews , Brian Bergman , Chung-Yuen Hui , Anand Jagota

The dynamics of dense particle packings near the jamming transition is characterized by correlated particle motion. The growth of dynamical heterogeneities, or strong spatial variations in the motion of the particles constituting the…

Soft Condensed Matter · Physics 2024-09-12 Rajkumar Biswas , Anoop Mutneja , Smarajit Karmakar , Ranjini Bandyopadhyay

Collective motion of self-propelled organisms or synthetic particles often termed active fluid has attracted enormous attention in broad scientific community because of it fundamentally non-equilibrium nature. Energy input and interactions…

Soft Condensed Matter · Physics 2014-03-05 Shuang Zhou , Andrey Sokolov , Oleg D Lavrentovich , Igor S Aranson

Combining experiments and theory, we address the dynamics of self-propelled particles in crowded environments. We first demonstrate that motile colloids cruising at constant speed through random lattices undergo a smooth transition from…

Soft Condensed Matter · Physics 2017-11-01 Alexandre Morin , David Lopes Cardozo , Vijayakumar Chikkadi , Denis Bartolo

We used x-ray photon correlation spectroscopy to study the dynamics in the lamellar phase of a platelet suspension as a function of the particle concentration. We measured the collective diffusion coefficient along the director of the…

Soft Condensed Matter · Physics 2015-04-07 Doru Constantin , Patrick Davidson , Éric Freyssingeas , Anders Madsen

Diffusion of a solute along a channel is enhanced by hydrodynamic flow, a phenomenon known as Taylor dispersion. In microfluidic applications, the compliance of the channel boundaries modifies the hydrodynamic flow and thus solutal…

Soft Condensed Matter · Physics 2026-04-08 Aditya Jha , Masoodah Gunny , Joshua D Mcgraw , Yacine Amarouchene , Thomas Salez

Diffusion in cell biology is important and complicated. Diffusing particles must contend with a complex environment as they make their way through the cell. We analyze a particular type of complexity that arises when diffusing particles…

Subcellular Processes · Quantitative Biology 2018-09-06 Ben Fogelson , James P. Keener

In many physical systems, degrees of freedom are coupled \emph{via} hydrodynamic forces, even in the absence of Hamiltonian interactions. A particularly important and widespread example concerns the transport of microscopic particles in…

Soft Condensed Matter · Physics 2025-02-11 Juliette Lacherez , Maxime Lavaud , Yacine Amarouchene , David S. Dean , Thomas Salez

Lipid structures exhibit complex and highly dynamic lateral structure; and changes in lipid density and fluidity are believed to play an essential role in membrane targeting and function. The dynamic structure of liquids on the molecular…

Soft Condensed Matter · Physics 2016-12-21 Neda Dadashvand , Christina M. Othon

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

Elastohydrodynamic lubrication, or simply soft lubrication, refers to the motion of deformable objects near a boundary lubricated by a fluid, and is one of the key physical mechanisms to minimise friction and wear in natural and engineered…

Fluid Dynamics · Physics 2021-04-07 Martin Essink , Anupam Pandey , Stefan Karpitschka , Kees Venner , Jacco Snoeijer

Cellular membranes are a heterogeneous mix of lipids, proteins and small molecules. Special groupings of saturated lipids and cholesterol form a liquid-ordered phase, known as `lipid rafts,' serving as platforms for signaling, trafficking…

Quantitative Methods · Quantitative Biology 2015-05-13 Tristan S. Ursell , William S. Klug , Rob Phillips

The mobility of water molecules confined in a silica pore is studied by computer simulation in the low hydration regime, where most of the molecules reside close to the hydrophilic substrate. A layer analysis of the single particle dynamics…

Statistical Mechanics · Physics 2009-11-10 P. Gallo , M. Rovere

We present a dynamical model of lipoprotein metabolism derived by combining a cascading process in the blood stream and cellular level regulatory dynamics. We analyse the existence and stability of equilibria and show that this…

Quantitative Methods · Quantitative Biology 2007-05-23 Elias August , Kim H. Parker , Mauricio Barahona