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The aim of this study is to propose an alternative and hybrid solution method for diagnosing the disease from histopathology images taken from animals with paratuberculosis and intact intestine. In detail, the hybrid method is based on…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Nilgun Sengoz , Tuncay Yigit , Ozlem Ozmen , Ali Hakan Isik

The rapidly emerging field of deep learning-based computational pathology has shown promising results in utilizing whole slide images (WSIs) to objectively prognosticate cancer patients. However, most prognostic methods are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Mingxin Liu , Yunzan Liu , Hui Cui , Chunquan Li , Jiquan Ma

Artificial intelligence-enabled histopathological data analysis has become a valuable assistant to the pathologist. However, existing models lack representation and inference abilities compared with those of pathologists, especially in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-20 Bo Yu , Hechang Chen , Yunke Zhang , Lele Cong , Shuchao Pang , Hongren Zhou , Ziye Wang , Xianling Cong

With the rise of deep learning, there has been increased interest in using neural networks for histopathology image analysis, a field that investigates the properties of biopsy or resected specimens traditionally manually examined under a…

Deep neural networks (DNNs) have exhibited remarkable success in the field of histopathology image analysis. On the other hand, the contemporary trend of employing large models and extensive datasets has underscored the significance of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Cong Cong , Shiyu Xuan , Sidong Liu , Maurice Pagnucco , Shiliang Zhang , Yang Song

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

Glaucomatous optic neuropathy (GON) is a prevalent ocular disease that can lead to irreversible vision loss if not detected early and treated. The traditional diagnostic approach for GON involves a set of ophthalmic examinations, which are…

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

Image and Video Processing · Electrical Eng. & Systems 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

Accurate polyp segmentation in colonoscopy is essential for cancer prevention but remains challenging due to: (1) high morphological variability (from flat to protruding lesions), (2) strong visual similarity to normal structures such as…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Abdul Joseph Fofanah , Lian Wen , Alpha Alimamy Kamara , Zhongyi Zhang , David Chen , Albert Patrick Sankoh

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-15 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Maode Lai , Eric I-Chao Chang

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Honglong Yang , Shanshan Song , Yi Qin , Lehan Wang , Haonan Wang , Xinpeng Ding , Qixiang Zhang , Bodong Du , Xiaomeng Li

Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Ayushi Raj Bhatt , Rajkumar Vaghashiya , Meghna Kulkarni , Dr Prakash Kamaraj

Intestinal parasites are responsible for several diseases in human beings. In order to eliminate the error-prone visual analysis of optical microscopy slides, we have investigated automated, fast, and low-cost systems for the diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 D. Osaku , C. F. Cuba , Celso T. N. Suzuki , J. F. Gomes , A. X. Falcão

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi