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While diffusion-based models have shown remarkable generative capabilities in static settings, their extension to continual learning (CL) scenarios remains fundamentally constrained by Generative Catastrophic Forgetting (GCF). We observe…

Machine Learning · Computer Science 2025-08-25 Jingren Liu , Shuning Xu , Yun Wang , Zhong Ji , Xiangyu Chen

Guidance is a cornerstone of modern diffusion models, playing a pivotal role in conditional generation and enhancing the quality of unconditional samples. However, current approaches to guidance scheduling--determining the appropriate…

Controllable generation is considered a potentially vital approach to address the challenge of annotating 3D data, and the precision of such controllable generation becomes particularly imperative in the context of data production for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Jinhua Zhang , Hualian Sheng , Sijia Cai , Bing Deng , Qiao Liang , Wen Li , Ying Fu , Jieping Ye , Shuhang Gu

Large-scale generative models are capable of producing high-quality images from detailed text descriptions. However, many aspects of an image are difficult or impossible to convey through text. We introduce self-guidance, a method that…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Dave Epstein , Allan Jabri , Ben Poole , Alexei A. Efros , Aleksander Holynski

Object-centric learning aims to represent visual data with a set of object entities (a.k.a. slots), providing structured representations that enable systematic generalization. Leveraging advanced architectures like Transformers, recent…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Ziyi Wu , Jingyu Hu , Wuyue Lu , Igor Gilitschenski , Animesh Garg

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Diffusion models have demonstrated significant promise in various generative tasks; however, they often struggle to satisfy challenging constraints. Our approach addresses this limitation by rethinking training-free loss-guided diffusion…

Machine Learning · Computer Science 2024-11-19 William Huang , Yifeng Jiang , Tom Van Wouwe , C. Karen Liu

Conditional diffusion models have achieved remarkable success in various generative tasks recently, but their training typically relies on large-scale datasets that inevitably contain imprecise information in conditional inputs. Such…

Machine Learning · Computer Science 2025-10-13 Dong-Dong Wu , Jiacheng Cui , Wei Wang , Zhiqiang Shen , Masashi Sugiyama

Masked diffusion models have demonstrated competitive results on various tasks including language generation. However, due to its iterative refinement process, the inference is often bottlenecked by slow and static sampling speed. To…

Machine Learning · Computer Science 2026-03-09 Seo Hyun Kim , Sunwoo Hong , Hojung Jung , Youngrok Park , Se-Young Yun

We present ControlSR, a new method that can tame Diffusion Models for consistent real-world image super-resolution (Real-ISR). Previous Real-ISR models mostly focus on how to activate more generative priors of text-to-image diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yuhao Wan , Peng-Tao Jiang , Qibin Hou , Hao Zhang , Jinwei Chen , Ming-Ming Cheng , Bo Li

Predictive models trained on imbalanced data tend to produce biased results. This problem is exacerbated when there is not just one output label, but a set of them. This is the case for multilabel learning (MLL) algorithms used to classify…

Machine Learning · Computer Science 2025-01-22 Francisco Charte , Miguel Ángel Dávila , María Dolores Pérez-Godoy , María José del Jesus

Controllable image generation has always been one of the core demands in image generation, aiming to create images that are both creative and logical while satisfying additional specified conditions. In the post-AIGC era, controllable…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Guandong Li

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang

Classifier-Free Guidance (CFG) is a widely used mechanism for controlling diffusion-based generative models, yet its guidance scale is typically treated as a fixed hyperparameter throughout generation. This static design yields a suboptimal…

Computation and Language · Computer Science 2026-05-11 Fan Zhou , Tim Van de Cruys

Recently, 3D generative models have shown promising performances in structure-based drug design by learning to generate ligands given target binding sites. However, only modeling the target-ligand distribution can hardly fulfill one of the…

Biomolecules · Quantitative Biology 2024-03-22 Xiangxin Zhou , Xiwei Cheng , Yuwei Yang , Yu Bao , Liang Wang , Quanquan Gu

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Diffusion policy sampling enables reinforcement learning (RL) to represent multimodal action distributions beyond suboptimal unimodal Gaussian policies. However, existing diffusion-based RL methods primarily focus on offline settings for…

Machine Learning · Computer Science 2026-05-07 Xiaoyuan Cheng , Wenxuan Yuan , Boyang Li , Yuanchao Xu , Yiming Yang , Hao Liang , Bei Peng , Robert Loftin , Zhuo Sun , Yukun Hu

Diffusion models have become popular for policy learning in robotics due to their ability to capture high-dimensional and multimodal distributions. However, diffusion policies are stochastic and typically trained offline, limiting their…

Robotics · Computer Science 2025-05-28 Ralf Römer , Alexander von Rohr , Angela P. Schoellig

Diffusion Models (DM) and Consistency Models (CM) are two types of popular generative models with good generation quality on various tasks. When training DM and CM, intermediate weight checkpoints are not fully utilized and only the last…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Enshu Liu , Junyi Zhu , Zinan Lin , Xuefei Ning , Shuaiqi Wang , Matthew B. Blaschko , Sergey Yekhanin , Shengen Yan , Guohao Dai , Huazhong Yang , Yu Wang

Discrete diffusion models are a class of generative models that produce samples from an approximated data distribution within a discrete state space. Often, there is a need to target specific regions of the data distribution. Current…

Machine Learning · Computer Science 2025-09-03 Cheuk Kit Lee , Paul Jeha , Jes Frellsen , Pietro Lio , Michael Samuel Albergo , Francisco Vargas