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The success of large language models (LLMs) in scientific domains has heightened safety concerns, prompting numerous benchmarks to evaluate their scientific safety. Existing benchmarks often suffer from limited risk coverage and a reliance…

Artificial Intelligence (AI) is revolutionizing scientific research, yet its growing integration into laboratory environments presents critical safety challenges. Large language models (LLMs) and vision language models (VLMs) now assist in…

Large language models (LLMs) have a transformative impact on a variety of scientific tasks across disciplines including biology, chemistry, medicine, and physics. However, ensuring the safety alignment of these models in scientific research…

The advancement and extensive application of large language models (LLMs) have been remarkable, including their use in scientific research assistance. However, these models often generate scientifically incorrect or unsafe responses, and in…

Computation and Language · Computer Science 2024-11-28 Haochen Zhao , Xiangru Tang , Ziran Yang , Xiao Han , Xuanzhi Feng , Yueqing Fan , Senhao Cheng , Di Jin , Yilun Zhao , Arman Cohan , Mark Gerstein

With the growing prevalence of large language models (LLMs), the safety of LLMs has raised significant concerns. However, there is still a lack of definitive standards for evaluating their safety due to the subjective nature of current…

Computation and Language · Computer Science 2025-06-10 Chuxue Cao , Han Zhu , Jiaming Ji , Qichao Sun , Zhenghao Zhu , Yinyu Wu , Juntao Dai , Yaodong Yang , Sirui Han , Yike Guo

Ensuring the safety of large language model (LLM) applications is essential for developing trustworthy artificial intelligence. Current LLM safety benchmarks have two limitations. First, they focus solely on either discriminative or…

Computation and Language · Computer Science 2024-10-30 Yutao Mou , Shikun Zhang , Wei Ye

Misalignment in Large Language Models (LLMs) arises when model behavior diverges from human expectations and fails to simultaneously satisfy safety, value, and cultural dimensions, which must co-occur in real-world settings to solve a…

Computation and Language · Computer Science 2026-02-13 Usman Naseem , Gautam Siddharth Kashyap , Rafiq Ali , Ebad Shabbir , Sushant Kumar Ray , Abdullah Mohammad , Agrima Seth

With the rapid development of Large Language Models (LLMs), increasing attention has been paid to their safety concerns. Consequently, evaluating the safety of LLMs has become an essential task for facilitating the broad applications of…

Computation and Language · Computer Science 2024-06-25 Zhexin Zhang , Leqi Lei , Lindong Wu , Rui Sun , Yongkang Huang , Chong Long , Xiao Liu , Xuanyu Lei , Jie Tang , Minlie Huang

Despite the remarkable proficiency of \textit{Large Reasoning Models} (LRMs) in handling complex reasoning tasks, their reliability in safety-critical scenarios remains uncertain. Existing evaluations primarily assess response-level safety,…

Artificial Intelligence · Computer Science 2025-05-27 Baihui Zheng , Boren Zheng , Kerui Cao , Yingshui Tan , Zhendong Liu , Weixun Wang , Jiaheng Liu , Jian Yang , Wenbo Su , Xiaoyong Zhu , Bo Zheng , Kaifu Zhang

With the profound development of large language models(LLMs), their safety concerns have garnered increasing attention. However, there is a scarcity of Chinese safety benchmarks for LLMs, and the existing safety taxonomies are inadequate,…

Computation and Language · Computer Science 2024-09-04 Wenjing Zhang , Xuejiao Lei , Zhaoxiang Liu , Meijuan An , Bikun Yang , KaiKai Zhao , Kai Wang , Shiguo Lian

Large language models (LLMs) hold promise in clinical decision support but face major challenges in safety evaluation and effectiveness validation. We developed the Clinical Safety-Effectiveness Dual-Track Benchmark (CSEDB), a…

As large language models (LLMs) develop increasingly sophisticated capabilities and find applications in medical settings, it becomes important to assess their medical safety due to their far-reaching implications for personal and public…

Artificial Intelligence · Computer Science 2024-10-11 Tessa Han , Aounon Kumar , Chirag Agarwal , Himabindu Lakkaraju

As the performance of large language models (LLMs) continues to advance, their adoption in the medical domain is increasing. However, most existing risk evaluations largely focused on general safety benchmarks. In the medical applications,…

Computation and Language · Computer Science 2026-01-12 Jean-Philippe Corbeil , Minseon Kim , Maxime Griot , Sheela Agarwal , Alessandro Sordoni , Francois Beaulieu , Paul Vozila

Multimodal Large Language Models (MLLMs) have demonstrated significant potential to advance a broad range of domains. However, current benchmarks for evaluating MLLMs primarily emphasize general knowledge and vertical step-by-step reasoning…

The rapid proliferation of large language models (LLMs) in applications targeting children and adolescents necessitates a fundamental reassessment of prevailing AI safety frameworks, which are largely tailored to adult users and neglect the…

Computation and Language · Computer Science 2025-12-16 Wenpeng Xing , Lanyi Wei , Haixiao Hu , Jingyi Yu , Rongchang Li , Mohan Li , Changting Lin , Meng Han

Evaluating aligned large language models' (LLMs) ability to recognize and reject unsafe user requests is crucial for safe, policy-compliant deployments. Existing evaluation efforts, however, face three limitations that we address with…

Safety alignment in Large Language Models is critical for healthcare; however, reliance on binary refusal boundaries often results in \emph{over-refusal} of benign queries or \emph{unsafe compliance} with harmful ones. While existing…

Artificial Intelligence · Computer Science 2026-01-27 Zhihao Zhang , Liting Huang , Guanghao Wu , Preslav Nakov , Heng Ji , Usman Naseem

Large language models (LLMs) are increasingly applied in financial scenarios. However, they may produce harmful outputs, including facilitating illegal activities or unethical behavior, posing serious compliance risks. To systematically…

Computation and Language · Computer Science 2026-05-04 Yutao Hou , Yihan Jiang , Yuhan Xie , Jian Yang , Liwen Zhang , Hailiang Huang , Guanhua Chen , Yun Chen

Large Reasoning Models (LRMs) have significantly improved problem-solving through explicit Chain-of-Thought (CoT) reasoning. However, this capability creates a Safety-Helpfulness Paradox: the reasoning process itself can be misused to…

Artificial Intelligence · Computer Science 2026-01-27 Xin Gao , Shaohan Yu , Zerui Chen , Yueming Lyu , Weichen Yu , Guanghao Li , Jiyao Liu , Jianxiong Gao , Jian Liang , Ziwei Liu , Chenyang Si

Large Language Models (LLMs) require careful safety alignment to prevent malicious outputs. While significant research focuses on mitigating harmful content generation, the enhanced safety often come with the side effect of over-refusal,…

Computation and Language · Computer Science 2025-06-17 Justin Cui , Wei-Lin Chiang , Ion Stoica , Cho-Jui Hsieh
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