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The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

Molecularly targeted contrast enhanced ultrasound (mCEUS) is a clinically promising approach for early cancer detection through targeted imaging of VEGFR2 (KDR) receptors. We have developed computational enhancement techniques for mCEUS…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Andrew A. Berlin , Mon Young , Ahmed El Kaffas , Sam Gambhir , Amelie Lutz , Maria Luigia Storto , Juergen Willmann

Masked autoencoders (MAEs) have displayed significant potential in the classification and semantic segmentation of medical images in the last year. Due to the high similarity of human tissues, even slight changes in medical images may…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Jiawei Mao , Shujian Guo , Yuanqi Chang , Xuesong Yin , Binling Nie

Multi-Energy Computed Tomography (ME-CT) is a medical imaging modality aiming to reconstruct the spatial density of materials from the attenuation properties of probing x-rays. For each line in two- or three-dimensional space, ME-CT…

Numerical Analysis · Mathematics 2020-06-24 Guillaume Bal , Fatma Terzioglu

Tissues are fractal due to its self-similar structure, and the fractal dimension change with the abnormalities such as in disease like cancer. The optical imaging of thin slices of tissue using transmission microscopy can produce an…

Biological Physics · Physics 2020-12-29 Liam Elkington , Prakash Adhikari , Prabhakar Pradhan

Recent advancements in model checking have demonstrated significant potential across diverse applications, particularly in signal and image analysis. Medical imaging stands out as a critical domain where model checking can be effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Elhoucine Elfatimi , Lahcen El fatimi

In the field of medical imaging, AI-assisted techniques such as object detection, segmentation, and classification are widely employed to alleviate the workload of physicians and doctors. However, single-task models are predominantly used,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Fan Li , Arun Iyengar , Lanyu Xu

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Cancer is one of the most common diseases worldwide, posing a serious threat to human health and leading to the deaths of a large number of people. It was observed during the drug administration in chemotherapy that immune cells, cancer…

Quantitative Methods · Quantitative Biology 2020-08-20 SeyedMehdi Abtahi , Mojtaba Sharifi

In this paper, we report a hidden Markov model based multiclass classification of cervical cancer tissues. This model has been validated directly over time series generated by the medium refractive index fluctuations extracted from…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Sabyasachi Mukhopadhyay , Sanket Nandan , Indrajit Kurmi

This work is motivated by multimodality breast cancer imaging data, which is quite challenging in that the signals of discrete tumor-associated microvesicles (TMVs) are randomly distributed with heterogeneous patterns. This imposes a…

Machine Learning · Statistics 2019-03-22 Xiwei Tang , Xuan Bi , Annie Qu

Precision medicine promises to transform health care by offering individualised treatments that dramatically improve clinical outcomes. A necessary prerequisite is to identify subgroups of patients who respond differently to different…

Machine Learning · Computer Science 2026-03-03 Adam Marcus , Paul Agapow

The primary objective of phase I cancer clinical trials is to evaluate the safety of a new experimental treatment and to find the maximum tolerated dose (MTD). We show that the MTD estimation problem can be regarded as a level set…

Machine Learning · Statistics 2025-04-15 Keiichiro Seno , Kota Matsui , Shogo Iwazaki , Yu Inatsu , Shion Takeno , Shigeyuki Matsui

Accurate and efficient classification of different types of cancer is critical for early detection and effective treatment. In this paper, we present the results of our experiments using the EfficientNet algorithm for classification of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Romario Sameh Samir

Artificial intelligence (AI) has significantly improved medical screening accuracy, particularly in cancer detection and risk assessment. However, traditional classification metrics often fail to account for imbalanced data, varying…

Machine Learning · Computer Science 2025-10-28 Longfei Wei , Fang Sheng , Jianfei Zhang

This paper proposes a general framework for probabilistic certification of cancer therapies. The certification is defined in terms of two key issues which are the tumor contraction and the lower admissible bound on the circulating…

Systems and Control · Computer Science 2015-02-24 Mazen Alamir

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Adopting Convolutional Neural Networks (CNNs) in the daily routine of primary diagnosis requires not only near-perfect precision, but also a sufficient degree of generalization to data acquisition shifts and transparency. Existing CNN…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Mara Graziani , Sebastian Otalora , Stephane Marchand-Maillet , Henning Muller , Vincent Andrearczyk

One of the most relevant prognostication tests for tumors is cellular proliferation, which is most commonly measured by the mitotic activity in routine tumor sections. The goal of this systematic review is to scholarly analyze the methods…

Subcellular Processes · Quantitative Biology 2024-04-17 Christof A. Bertram , Taryn A. Donovan , Alexander Bartel

Accurate subtype classification and outcome prediction in mesothelioma are essential for guiding therapy and patient care. Most computational pathology models are trained on large tissue images from resection specimens, limiting their use…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Farzaneh Seyedshahi , Francesca Damiola , Sylvie Lantuejoul , Ke Yuan , John Le Quesne