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Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

For several purposes in Natural Language Processing (NLP), such as Information Extraction, Sentiment Analysis or Chatbot, Named Entity Recognition (NER) holds an important role as it helps to determine and categorize entities in text into…

Computation and Language · Computer Science 2020-03-24 Thong Nguyen , Duy Nguyen , Pramod Rao

The trade-off between interpretability and accuracy remains a core challenge in machine learning. Standard Generalized Additive Models (GAMs) offer clear feature attributions but are often constrained by their strictly additive nature,…

Machine Learning · Computer Science 2026-02-12 Guangzhi Xiong , Sanchit Sinha , Aidong Zhang

Deep CNNs have been pushing the frontier of visual recognition over past years. Besides recognition accuracy, strong demands in understanding deep CNNs in the research community motivate developments of tools to dissect pre-trained models…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Bangjie Yin , Luan Tran , Haoxiang Li , Xiaohui Shen , Xiaoming Liu

Interpretability is one of the considerations when applying machine learning to high-stakes fields such as healthcare that involve matters of life safety. Generalized Additive Models (GAMs) enhance interpretability by visualizing shape…

Machine Learning · Computer Science 2025-10-06 Fumin Wang

In this position paper, we study interactive learning for structured output spaces, with a focus on active learning, in which labels are unknown and must be acquired, and on skeptical learning, in which the labels are noisy and may need…

Machine Learning · Computer Science 2022-02-18 Stefano Teso , Antonio Vergari

In this paper, we address the critical need for interpretable and uncertainty-aware machine learning models in the context of online learning for high-risk industries, particularly cyber-security. While deep learning and other complex…

Machine Learning · Computer Science 2024-11-15 Benjamin Kolicic , Alberto Caron , Chris Hicks , Vasilios Mavroudis

Hazard and survival functions are natural, interpretable targets in time-to-event prediction, but their inherent non-additivity fundamentally limits standard additive explanation methods. We introduce Survival Functional Decomposition…

Machine learning algorithms often assume that training samples are independent. When data points are connected by a network, the induced dependency between samples is both a challenge, reducing effective sample size, and an opportunity to…

Machine Learning · Statistics 2025-09-22 Tiffany M. Tang , Elizaveta Levina , Ji Zhu

In this article, we propose a novel form of unsupervised learning, continual competitive memory (CCM), as well as a computational framework to unify related neural models that operate under the principles of competition. The resulting…

Machine Learning · Computer Science 2021-06-28 Alexander G. Ororbia

As data shift or new data become available, updating clinical machine learning models may be necessary to maintain or improve performance over time. However, updating a model can introduce compatibility issues when the behavior of the…

Machine Learning · Statistics 2023-08-11 Erkin Ötleş , Brian T. Denton , Jenna Wiens

Recent models for image processing are using the Convolutional neural network (CNN) which requires a pixel per pixel analysis of the input image. This method works well. However, it is time-consuming if we have large images. To increase the…

Machine Learning · Computer Science 2019-12-10 Mohamed Karim Belaid

The lack of interpretability is an inevitable problem when using neural network models in real applications. In this paper, an explainable neural network based on generalized additive models with structured interactions (GAMI-Net) is…

Machine Learning · Statistics 2021-06-03 Zebin Yang , Aijun Zhang , Agus Sudjianto

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Aiman Farooq , Utkarsh Sharma , Deepak Mishra

Federated learning has significantly advanced distributed training of machine learning models across decentralized data sources. However, existing frameworks often lack comprehensive solutions that combine uncertainty quantification,…

Machine Learning · Computer Science 2025-07-01 Sree Bhargavi Balija , Amitash Nanda , Debashis Sahoo

Interpretable insights from predictive models remain critical in bio-statistics, particularly when assessing causality, where classical statistical and machine learning methods often provide inherent clarity. While Neural Networks (NNs)…

Applications · Statistics 2025-05-02 Jean-Baptiste A. Conan

With the proliferation of models for natural language processing tasks, it is even harder to understand the differences between models and their relative merits. Simply looking at differences between holistic metrics such as accuracy, BLEU,…

Computation and Language · Computer Science 2020-12-10 Jinlan Fu , Pengfei Liu , Graham Neubig

Research Replication Prediction (RRP) is the task of predicting whether a published research result can be replicated or not. Building an interpretable neural text classifier for RRP promotes the understanding of why a research paper is…

Computation and Language · Computer Science 2022-03-29 Tianyi Luo , Rui Meng , Xin Eric Wang , Yang Liu

Probabilistic survival predictions from models trained with Maximum Likelihood Estimation (MLE) can have high, and sometimes unacceptably high variance. The field of meteorology, where the paradigm of maximizing sharpness subject to…

Machine Learning · Computer Science 2019-06-20 Anand Avati , Tony Duan , Sharon Zhou , Kenneth Jung , Nigam H. Shah , Andrew Ng
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