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Microscopy-based phenotypic profiling is scalable for drug discovery but lacks the mechanistic depth of transcriptomics, which remains costly and scarce. Existing multimodal approaches either use images to support other modalities or…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Jiayuan Chen , Ruoqi Liu , Zishan Gu , Ping Zhang

Spatial transcriptomics provides a molecularly rich description of tissue organization, enabling unsupervised discovery of tissue niches -- spatially coherent regions of distinct cell-type composition and function that are relevant to both…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Arbel Hizmi , Artemii Bakulin , Shai Bagon , Nir Yosef

Deep learning achieved great progress recently, however, it is not easy or efficient to further improve its performance by increasing the size of the model. Multi-modal learning can mitigate this challenge by introducing richer and more…

Artificial Intelligence · Computer Science 2025-10-07 Cairong Zhao , Yufeng Jin , Zifan Song , Haonan Chen , Duoqian Miao , Guosheng Hu

Semi-supervised learning for medical image segmentation presents a unique challenge of efficiently using limited labeled data while leveraging abundant unlabeled data. Despite advancements, existing methods often do not fully exploit the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Bin Zhao , Chunshi Wang , Shuxue Ding

We present Distill CLIP (DCLIP), a fine-tuned variant of the CLIP model that enhances multimodal image-text retrieval while preserving the original model's strong zero-shot classification capabilities. CLIP models are typically constrained…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Daniel Csizmadia , Andrei Codreanu , Victor Sim , Vighnesh Prabhu , Michael Lu , Kevin Zhu , Sean O'Brien , Vasu Sharma

Dataset distillation aims to create a small and highly representative synthetic dataset that preserves the essential information of a larger real dataset. Beyond reducing storage and computational costs, related approaches offer a promising…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Zhe Li , Hadrien Reynaud , Bernhard Kainz

Improving the performance of semantic segmentation models using multispectral information is crucial, especially for environments with low-light and adverse conditions. Multi-modal fusion techniques pursue either the learning of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-06 Aniruddh Sikdar , Jayant Teotia , Suresh Sundaram

In recent years, pre-trained multimodal large models have attracted widespread attention due to their outstanding performance in various multimodal applications. Nonetheless, the extensive computational resources and vast datasets required…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Zhengyang Liang , Meiyu Liang , Wei Huang , Yawen Li , Zhe Xue

Integrating histopathology with spatial transcriptomics (ST) provides a powerful opportunity to link tissue morphology with molecular function. Yet most existing multimodal approaches rely on a small set of highly variable genes, which…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sejuti Majumder , Saarthak Kapse , Moinak Bhattacharya , Xuan Xu , Alisa Yurovsky , Prateek Prasanna

Multimodal fusion leverages information across modalities to learn better feature representations with the goal of improving performance in fusion-based tasks. However, multimodal datasets, especially in medical settings, are typically…

Machine Learning · Computer Science 2025-02-05 Alejandro Guerra-Manzanares , Farah E. Shamout

Having access to multi-modal cues (e.g. vision and audio) empowers some cognitive tasks to be done faster compared to learning from a single modality. In this work, we propose to transfer knowledge across heterogeneous modalities, even…

Computer Vision and Pattern Recognition · Computer Science 2021-04-23 Yanbei Chen , Yongqin Xian , A. Sophia Koepke , Ying Shan , Zeynep Akata

While deep learning methods have shown great success in medical image analysis, they require a number of medical images to train. Due to data privacy concerns and unavailability of medical annotators, it is oftentimes very difficult to…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Yue Yang , Pengtao Xie

The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Kang Li , Lequan Yu , Shujun Wang , Pheng-Ann Heng

Electroencephalography (EEG) is a fundamental modality for cognitive state monitoring in brain-computer interfaces (BCIs). However, it is highly susceptible to intrinsic signal errors and human-induced labeling errors, which lead to label…

Machine Learning · Computer Science 2025-12-15 Hyo-Jeong Jang , Hye-Bin Shin , Seong-Whan Lee

Metric learning projects samples into an embedded space, where similarities and dissimilarities are quantified based on their learned representations. However, existing methods often rely on label-guided representation learning, where…

Sound · Computer Science 2025-01-17 Donghuo Zeng , Kazushi Ikeda

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Image Aesthetics Assessment (IAA) is a challenging task due to its subjective nature and expensive manual annotations. Recent large-scale vision-language models, such as Contrastive Language-Image Pre-training (CLIP), have shown their…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Liwu Xu , Jinjin Xu , Yuzhe Yang , Xilu Wang , Yijie Huang , Yaqian Li

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Recent advances in multimodal learning have achieved remarkable success across diverse vision-language tasks. However, such progress heavily relies on large-scale image-text datasets, making training costly and inefficient. Prior efforts in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Junhyeok Choi , Sangwoo Mo , Minwoo Chae

Learning based on multimodal data has attracted increasing interest recently. While a variety of sensory modalities can be collected for training, not all of them are always available in development scenarios, which raises the challenge to…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Shicai Wei , Yang Luo , Chunbo Luo
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