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The human brain represents the only known example of general intelligence that naturally aligns with human values. On a mere 20-watt power budget, the brain achieves robust learning and adaptive decision-making in ways that continue to…

Neurons and Cognition · Quantitative Biology 2025-08-12 PK Douglas

In this article, we review a class of neuro-mimetic computational models that we place under the label of spiking predictive coding. Specifically, we review the general framework of predictive processing in the context of neurons that emit…

Neurons and Cognition · Quantitative Biology 2024-09-10 Antony W. N'dri , William Gebhardt , Céline Teulière , Fleur Zeldenrust , Rajesh P. N. Rao , Jochen Triesch , Alexander Ororbia

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

Full scale simulations of neuronal network models of the brain are challenging due to the high density of connections between neurons. This contribution reports run times shorter than the simulated span of biological time for a full scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-10-04 Anno C. Kurth , Johanna Senk , Dennis Terhorst , Justin Finnerty , Markus Diesmann

Real-time simulation of a large-scale biologically representative spiking neural network is presented, through the use of a heterogeneous parallelisation scheme and SpiNNaker neuromorphic hardware. A published cortical microcircuit model is…

Emerging Technologies · Computer Science 2021-04-28 Oliver Rhodes , Luca Peres , Andrew G. D. Rowley , Andrew Gait , Luis A. Plana , Christian Brenninkmeijer , Steve B. Furber

Neuromorphic computing has come to refer to a variety of brain-inspired computers, devices, and models that contrast the pervasive von Neumann computer architecture. This biologically inspired approach has created highly connected synthetic…

Neural and Evolutionary Computing · Computer Science 2017-05-22 Catherine D. Schuman , Thomas E. Potok , Robert M. Patton , J. Douglas Birdwell , Mark E. Dean , Garrett S. Rose , James S. Plank

Neuromorphic engineering (NE) encompasses a diverse range of approaches to information processing that are inspired by neurobiological systems, and this feature distinguishes neuromorphic systems from conventional computing systems. The…

Computational models of cortical activity provide insight into the mechanisms of higher-order processing in the human brain including planning, perception and the control of movement. Activity in the cortex is ongoing even in the absence of…

Neurons and Cognition · Quantitative Biology 2023-07-07 Lysea Haggie , Thor Besier , Angus McMorland

There has been significant research over the past two decades in developing new platforms for spiking neural computation. Current neural computers are primarily developed to mimick biology. They use neural networks which can be trained to…

Neural and Evolutionary Computing · Computer Science 2015-07-23 Xavier Lagorce , Ryad Benosman

For energy-efficient computation in specialized neuromorphic hardware, we present spiking neural coding, an instantiation of a family of artificial neural models grounded in the theory of predictive coding. This model, the first of its…

Neural and Evolutionary Computing · Computer Science 2022-08-09 Alexander Ororbia

Simulation is a third pillar next to experiment and theory in the study of complex dynamic systems such as biological neural networks. Contemporary brain-scale networks correspond to directed graphs of a few million nodes, each with an…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-03 Jari Pronold , Jakob Jordan , Brian J. N. Wylie , Itaru Kitayama , Markus Diesmann , Susanne Kunkel

The field of computational modeling of the brain is advancing so rapidly that now it is possible to model large scale networks representing different brain regions with a high level of biological detail in terms of numbers and synapses. For…

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

While spike timing has been shown to carry detailed stimulus information at the sensory periphery, its possible role in network computation is less clear. Most models of computation by neural networks are based on population firing rates.…

Neurons and Cognition · Quantitative Biology 2015-07-17 Michael A. Schwemmer , Adrienne L. Fairhall , Sophie Denéve , Eric T. Shea-Brown

Simulation speed matters for neuroscientific research: this includes not only how quickly the simulated model time of a large-scale spiking neuronal network progresses, but also how long it takes to instantiate the network model in computer…

Neuromorphic computing is henceforth a major research field for both academic and industrial actors. As opposed to Von Neumann machines, brain-inspired processors aim at bringing closer the memory and the computational elements to…

Neural and Evolutionary Computing · Computer Science 2020-05-05 Maxence Bouvier , Alexandre Valentian , Thomas Mesquida , François Rummens , Marina Reyboz , Elisa Vianello , Edith Beigné

Neuromorphic computing is a non-von Neumann computing paradigm that performs computation by emulating the human brain. Neuromorphic systems are extremely energy-efficient and known to consume thousands of times less power than CPUs and…

Neural and Evolutionary Computing · Computer Science 2021-04-30 Prasanna Date , Catherine Schuman , Bill Kay , Thomas Potok

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

Despite its better bio-plausibility, goal-driven spiking neural network (SNN) has not achieved applicable performance for classifying biological spike trains, and showed little bio-functional similarities compared to traditional artificial…

Neurons and Cognition · Quantitative Biology 2023-03-15 Tengjun Liu , Yansong Chua , Yiwei Zhang , Yuxiao Ning , Pengfu Liu , Guihua Wan , Zijun Wan , Shaomin Zhang , Weidong Chen

Modern computational neuroscience strives to develop complex network models to explain dynamics and function of brains in health and disease. This process goes hand in hand with advancements in the theory of neuronal networks and increasing…

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