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Chemical reasoning usually involves complex, multi-step processes that demand precise calculations, where even minor errors can lead to cascading failures. Furthermore, large language models (LLMs) encounter difficulties handling…

Computation and Language · Computer Science 2025-01-14 Xiangru Tang , Tianyu Hu , Muyang Ye , Yanjun Shao , Xunjian Yin , Siru Ouyang , Wangchunshu Zhou , Pan Lu , Zhuosheng Zhang , Yilun Zhao , Arman Cohan , Mark Gerstein

Atomistic simulations are essential tools in chemistry and materials science, accelerating the discovery of novel catalysts, energy storage materials, and pharmaceuticals. However, running these simulations remains challenging due to the…

Chemical Physics · Physics 2025-06-11 Thang D. Pham , Aditya Tanikanti , Murat Keçeli

Agentic systems offer a potential path to solve complex clinical tasks through collaboration among specialized agents, augmented by tool use and external knowledge bases. Nevertheless, for chest X-ray (CXR) interpretation, prevailing…

Multiagent Systems · Computer Science 2026-04-16 Kai Zhang , Corey D Barrett , Jangwon Kim , Lichao Sun , Tara Taghavi , Krishnaram Kenthapadi

The emergence of agent-based systems represents a significant advancement in artificial intelligence, with growing applications in automated data extraction. However, chemical information extraction remains a formidable challenge due to the…

The design of alloys is a multi-scale problem that requires a holistic approach that involves retrieving relevant knowledge, applying advanced computational methods, conducting experimental validations, and analyzing the results, a process…

Artificial Intelligence · Computer Science 2024-07-16 Alireza Ghafarollahi , Markus J. Buehler

Autoresearch offers a flexible paradigm for automating scientific tasks, in which an AI agent proposes, implements, evaluates, and refines candidate solutions against a quantitative objective. Here, we use composition-based…

Materials Science · Physics 2026-05-15 Matteo Cobelli , Stefano Sanvito

Large Language Models (LLMs) promise to accelerate discovery by reasoning across the expanding scientific landscape. Yet, the challenge is no longer access to information but connecting it in meaningful, domain-spanning ways. In materials…

Artificial Intelligence · Computer Science 2026-02-10 Isabella A. Stewart , Tarjei Paule Hage , Yu-Chuan Hsu , Markus J. Buehler

Text-to-image generation has advanced rapidly, but existing models still struggle with faithfully composing multiple objects and preserving their attributes in complex scenes. We propose coDrawAgents, an interactive multi-agent dialogue…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Chunhan Li , Qifeng Wu , Jia-Hui Pan , Ka-Hei Hui , Jingyu Hu , Yuming Jiang , Bin Sheng , Xihui Liu , Wenjuan Gong , Zhengzhe Liu

The development of AI-assisted chemical synthesis tools requires comprehensive datasets covering diverse reaction types, yet current high-throughput experimental (HTE) approaches are expensive and limited in scope. Chemical literature…

Information Retrieval · Computer Science 2025-07-01 Kexin Chen , Yuyang Du , Junyou Li , Hanqun Cao , Menghao Guo , Xilin Dang , Lanqing Li , Jiezhong Qiu , Pheng Ann Heng , Guangyong Chen

Extracting implicit knowledge and logical reasoning abilities from large language models (LLMs) has consistently been a significant challenge. The advancement of multi-agent systems has further en-hanced the capabilities of LLMs. Inspired…

Artificial Intelligence · Computer Science 2025-09-23 Hailong Yang , Mingxian Gu , Renhuo Zhao , Fuping Hu , Zhaohong Deng , Yitang Chen

Recently large vision-language models have shown potential when interpreting complex images and generating natural language descriptions using advanced reasoning. Medicine's inherently multimodal nature incorporating scans and text-based…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Naman Sharma

The transition from optical identification of 2D quantum materials to practical device fabrication requires dynamic reasoning beyond the detection accuracy. While recent domain-specific Multimodal Large Language Models (MLLMs) successfully…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Sankalp Pandey , Xuan-Bac Nguyen , Hoang-Quan Nguyen , Tim Faltermeier , Nicholas Borys , Hugh Churchill , Khoa Luu

Solving mechanics problems using numerical methods requires comprehensive intelligent capability of retrieving relevant knowledge and theory, constructing and executing codes, analyzing the results, a task that has thus far mainly been…

Artificial Intelligence · Computer Science 2023-11-15 Bo Ni , Markus J. Buehler

The development of chemical processes, a cornerstone of chemical engineering, presents formidable challenges due to its multi-faceted nature, integrating specialized knowledge, conceptual design, and parametric simulation. Capitalizing on…

Artificial Intelligence · Computer Science 2026-03-03 Yuhang Yang , Ruikang Li , Jifei Ma , Kai Zhang , Qi Liu , Jianyu Han , Yonggan Bu , Jibin Zhou , Defu Lian , Xin Li , Enhong Chen

As cosmological simulations and their associated software become increasingly complex, physicists face the challenge of searching through vast amounts of literature and user manuals to extract simulation parameters from dense academic…

Instrumentation and Methods for Astrophysics · Physics 2025-07-21 Xiaowen Zhang , Zhenyu Bi , Patrick Lachance , Xuan Wang , Tiziana Di Matteo , Rupert A. C. Croft

To fully expedite AI-powered chemical research, high-quality chemical databases are the foundation. Automatic extraction of chemical information from the literature is essential for constructing reaction databases, but it is currently…

Artificial Intelligence · Computer Science 2026-03-09 Yufan Chen , Ching Ting Leung , Bowen Yu , Jianwei Sun , Yong Huang , Linyan Li , Hao Chen , Hanyu Gao

Explaining observed phenomena through symbolic, interpretable formulas is a fundamental goal of science. Recently, large language models (LLMs) have emerged as promising tools for symbolic equation discovery, owing to their broad domain…

Artificial Intelligence · Computer Science 2026-02-26 Jianke Yang , Ohm Venkatachalam , Mohammad Kianezhad , Sharvaree Vadgama , Rose Yu

Recent multimodal LLMs have shown promise in chart-based visual question answering, but their performance declines sharply on unannotated charts-those requiring precise visual interpretation rather than relying on textual shortcuts. To…

Artificial Intelligence · Computer Science 2026-01-08 Rachneet Kaur , Nishan Srishankar , Zhen Zeng , Sumitra Ganesh , Manuela Veloso

Existing AI-generated text detection methods heavily depend on large annotated datasets and external threshold tuning, restricting interpretability, adaptability, and zero-shot effectiveness. To address these limitations, we propose…

Computation and Language · Computer Science 2025-05-22 Jiatao Li , Mao Ye , Cheng Peng , Xunjian Yin , Xiaojun Wan

Recent work has shown how predictive modeling can endow agents with rich knowledge of their surroundings, improving their ability to act in complex environments. We propose question-answering as a general paradigm to decode and understand…

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