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Heterogeneous data are now ubiquitous in many applications in which correctly identifying the subgroups from a heterogeneous population is critical. Although there is an increasing body of literature on subgroup detection, existing methods…

Methodology · Statistics 2025-12-09 Jie Wu , Bo Zhang , Daoji Li , Zemin Zheng

Domain adaptation solves the learning problem in a target domain by leveraging the knowledge in a relevant source domain. While remarkable advances have been made, almost all existing domain adaptation methods heavily require large amounts…

Machine Learning · Computer Science 2021-10-13 Shuai Yang , Kui Yu , Fuyuan Cao , Lin Liu , Hao Wang , Jiuyong Li

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

Nonlinear machine-learning models are increasingly used to discover causal relationships in time-series data, yet the interpretation of their outputs remains poorly understood. In particular, causal scores produced by regularized neural…

Machine Learning · Computer Science 2026-05-27 Valentina Kuskova , Dmitry Zaytsev , Michael Coppedge

Causal inference methods are widely applied in the fields of medicine, policy, and economics. Central to these applications is the estimation of treatment effects to make decisions. Current methods make binary yes-or-no decisions based on…

Machine Learning · Computer Science 2020-04-24 Will Y. Zou , Smitha Shyam , Michael Mui , Mingshi Wang , Jan Pedersen , Zoubin Ghahramani

High-dimensional compositional data arise naturally in many applications such as metagenomic data analysis. The observed data lie in a high-dimensional simplex, and conventional statistical methods often fail to produce sensible results due…

Methodology · Statistics 2016-01-19 Yuanpei Cao , Wei Lin , Hongzhe Li

Motivated by the drawbacks of cloud-based federated learning (FL), cooperative federated edge learning (CFEL) has been proposed to improve efficiency for FL over mobile edge networks, where multiple edge servers collaboratively coordinate…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-11-22 Zhenxiao Zhang , Zhidong Gao , Yuanxiong Guo , Yanmin Gong

High-cardinality categorical features are a common characteristic of mixed-type tabular datasets. Existing generative model architectures struggle to learn the complexities of such data at scale, primarily due to the difficulty of…

Machine Learning · Computer Science 2025-01-30 Lee Carlin , Yuval Benjamini

Single-cell RNA sequencing enables high-resolution analysis of cellular heterogeneity, yet disentangling biological signal from batch effects remains a major challenge. Existing batch-correction algorithms suppress or discard batch-related…

Machine Learning · Computer Science 2025-11-07 Aixa X. Andrade , Son Nguyen , Austin Marckx , Albert Montillo

Causal effect estimation from observational data is a crucial but challenging task. Currently, only a limited number of data-driven causal effect estimation methods are available. These methods either provide only a bound estimation of the…

Methodology · Statistics 2020-11-10 Debo Cheng , Jiuyong Li , Lin Liu , Kui Yu , Thuc Duy Lee , Jixue Liu

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

Machine Learning · Computer Science 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

Temporal link prediction is crucial for rapidly growing social networks. Existing methods often overlook the underlying causal mechanisms that drive link formation, making it difficult for algorithms to adapt to complex structures that…

Machine Learning · Computer Science 2026-05-12 Hantong Feng , Duxin Chen , Wenwu Yu

With a large number of baseline covariates, we propose a new semi-parametric modeling strategy for heterogeneous treatment effect estimation and individualized treatment selection, which are two major goals in personalized medicine. We…

Methodology · Statistics 2021-08-12 Wenchuan Guo , Xiao-hua Zhou , Shujie Ma

We study identification in a binary choice panel data model with a single \emph{predetermined} binary covariate (i.e., a covariate sequentially exogenous conditional on lagged outcomes and covariates). The choice model is indexed by a…

Econometrics · Economics 2023-07-25 Stéphane Bonhomme , Kevin Dano , Bryan S. Graham

This paper develops a new model and estimation procedure for panel data that allows us to identify heterogeneous structural breaks. We model individual heterogeneity using a grouped pattern. For each group, we allow common structural breaks…

Econometrics · Economics 2018-11-27 Ryo Okui , Wendun Wang

OC-DeepIV is a neural network model designed for estimating causal effects. It characterizes heterogeneity by adding interaction features and reduces redundancy through orthogonal constraints. The model includes two feature extractors, one…

Econometrics · Economics 2025-06-04 Shunxin Yao

Interpretability plays a crucial role in the application of statistical learning to estimate heterogeneous treatment effects (HTE) in complex diseases. In this study, we leverage a rule-based workflow, namely causal rule learning (CRL), to…

Machine Learning · Computer Science 2025-11-24 Ying Wu , Hanzhong Liu , Kai Ren , Shujie Ma , Xiangyu Chang

Heterogeneity and comorbidity are two interwoven challenges associated with various healthcare problems that greatly hampered research on developing effective treatment and understanding of the underlying neurobiological mechanism. Very few…

Methodology · Statistics 2023-06-27 Richard A Watson , Hengrui Cai , Xinming An , Samuel McLean , Rui Song

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Estimation of causal effects is fundamental in situations were the underlying system will be subject to active interventions. Part of building a causal inference engine is defining how variables relate to each other, that is, defining the…

Methodology · Statistics 2021-03-02 Sergio Garrido , Stanislav S. Borysov , Jeppe Rich , Francisco C. Pereira