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Mobile microscopy is a newly formed field that emerged from a combination of optical microscopy capabilities and spread, functionality, and ever-increasing computing resources of mobile devices. Despite the idea of creating a system that…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 A. Kornilova , I. Kirilenko , D. Iarosh , V. Kutuev , M. Strutovsky

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-view, and phototoxicity. To overcome these limitations,…

Quantitative Methods · Quantitative Biology 2024-04-01 Leonor Morgado , Estibaliz Gómez-de-Mariscal , Hannah S. Heil , Ricardo Henriques

Clinical image interpretation is inherently multi-step and tool-centric: clinicians iteratively combine visual evidence with patient context, quantify findings, and refine their decisions through a sequence of specialized procedures. While…

Artificial Intelligence · Computer Science 2026-03-09 Lin Fan , Pengyu Dai , Zhipeng Deng , Haolin Wang , Xun Gong , Yefeng Zheng , Yafei Ou

This white paper lays out a vision of research and development in the field of artificial intelligence for the next decade (and beyond). Its denouement is a cyber-physical ecosystem of natural and synthetic sense-making, in which humans are…

Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep…

Imaging methods used in modern neuroscience experiments are quickly producing large amounts of data capable of providing increasing amounts of knowledge about neuroanatomy and function. A great deal of information in these datasets is…

Quantitative Methods · Quantitative Biology 2017-01-25 William Gray Roncal , Eva L Dyer , Doga Gürsoy , Konrad Kording , Narayanan Kasthuri

In today's world of big data, computational analysis has become a key driver of biomedical research. Recent exponential growth in the volume of available omics data has reshaped the landscape of contemporary biology, creating demand for a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-09 Jaqueline J. Brito , Thiago Mosqueiro , Jeremy Rotman , Victor Xue , Douglas J. Chapski , Juan De la Hoz , Paulo Matias , Lana Martin , Alex Zelikovsky , Matteo Pellegrinni , Serghei Mangul

Human-robot interactive decision-making is increasingly becoming ubiquitous, and trust is an influential factor in determining the reliance on autonomy. However, it is not reasonable to trust systems that are beyond our comprehension, and…

Machine Learning · Computer Science 2021-08-16 Daoming Lyu , Fangkai Yang , Hugh Kwon , Wen Dong , Levent Yilmaz , Bo Liu

This paper introduces Reflective Empiricism, an extension of empirical science that incorporates subjective perception and consciousness processes as equally valid sources of knowledge. It views reality as an interplay of subjective…

Physics and Society · Physics 2025-04-18 Oliver Marc Wittwer

Recent machine learning techniques have dramatically changed how we process digital images. However, the way in which we capture images is still largely driven by human intuition and experience. This restriction is in part due to the many…

Image and Video Processing · Electrical Eng. & Systems 2020-02-17 Amey Chaware , Colin L. Cooke , Kanghyun Kim , Roarke Horstmeyer

This paper presents a systematic solution for the intelligent recognition and automatic analysis of microscopy images. We developed a data engine that generates high-quality annotated datasets through a combination of the collection of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Yanhui Hong , Nan Wang , Zhiyi Xia , Haoyi Tao , Xi Fang , Yiming Li , Jiankun Wang , Peng Jin , Xiaochen Cai , Shengyu Li , Ziqi Chen , Zezhong Zhang , Guolin Ke , Linfeng Zhang

The integration of collaborative robots into industrial environments has improved productivity, but has also highlighted significant challenges related to operator safety and ergonomics. This paper proposes an innovative framework that…

Robotics · Computer Science 2025-04-15 Francesco Iodice , Elena De Momi , Arash Ajoudani

We offer a new model of the sensemaking process for data analysis and visualization. Whereas past sensemaking models have been grounded in positivist assumptions about the nature of knowledge, we reframe data sensemaking in critical,…

Human-Computer Interaction · Computer Science 2025-11-10 Charles Berret , Tamara Munzner

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Artificial intelligence (AI) promises to reshape scientific inquiry and enable breakthrough discoveries in areas such as energy storage, quantum computing, and biomedicine. Scanning transmission electron microscopy (STEM), a cornerstone of…

Scanning probe microscopy (SPM) is a valuable technique by which one can investigate the physical characteristics of the surfaces of materials. However, its widespread use is hampered by the time-consuming nature of running an experiment…

Instrumentation and Detectors · Physics 2025-09-03 Nicholas J. Sullivan , Julio J. Valdés , Kirk H. Bevan , Peter Grutter

Remote science operations require automated systems that can both act and react with minimal human intervention. One such vision is that of an intelligent instrument that collects data in an automated fashion, and based on what it learns,…

Artificial Intelligence · Computer Science 2016-02-24 Kevin H. Knuth , Philip M. Erner , Scott Frasso

Mathematical models are increasingly a part of microbiological research. Here, we share our perspective on how modeling advances the discipline by: (i) enforcing logical consistency, (ii) enabling quantitative prediction, (iii) extracting…

Other Quantitative Biology · Quantitative Biology 2026-04-22 Jamie A. Lopez , Amir Erez

Microscopy techniques have played vital roles in materials science, biology, and nanotechnology, offering high-resolution imaging and detailed insights into properties at nanoscale and atomic level. The automation of microscopy experiments,…

Materials Science · Physics 2024-08-06 Utkarsh Pratiush , Hiroshi Funakubo , Rama Vasudevan , Sergei V. Kalinin , Yongtao Liu

Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Kamyar Barakati , Yu Liu , Utkarsh Pratiush , Boris N. Slautin , Sergei V. Kalinin
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