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Finding optimal pathways in chemical reaction networks is essential for elucidating and designing chemical processes, with significant applications such as synthesis planning and metabolic pathway analysis. Such a chemical pathway-finding…

Quantum Physics · Physics 2024-01-31 Yuta Mizuno , Tamiki Komatsuzaki

The Travelling Salesman Problem (TSP) is an important combinatorial optimisation problem, and is usually solved on a quantum computer using a Quadratic Unconstrained Binary Optimisation (QUBO) formulation or a Higher Order Binary…

Quantum Physics · Physics 2024-06-21 Daniel Goldsmith , Joe Day-Evans

Ising machines have the potential to realize fast and highly accurate solvers for combinatorial optimization problems. They are classified based on their internal algorithms. Examples include simulated-annealing-based Ising machines…

Statistical Mechanics · Physics 2023-11-15 Shuta Kikuchi , Nozomu Togawa , Shu Tanaka

In recent years, hardware implementations of Ising machines have emerged as a viable alternative to quantum computing for solving hard optimization problems among other applications. Unlike quantum hardware, dense connectivity can be…

Oscillator Ising machines (OIMs) are networks of coupled oscillators that seek the minimum energy state of an Ising model. Since many NP-hard problems are equivalent to the minimization of an Ising Hamiltonian, OIMs have emerged as a…

Optimization and Control · Mathematics 2026-02-20 Ahmed Allibhoy , Arthur N. Montanari , Fabio Pasqualetti , Adilson E. Motter

A promising paradigm of quantum computing for achieving practical quantum advantages is quantum annealing or quantum approximate optimization algorithm, where the classical problems are encoded in Ising interactions. However, it is…

Quantum Physics · Physics 2025-06-25 Yao Lu , Wentao Chen , Shuaining Zhang , Kuan Zhang , Jialiang Zhang , Jing-Ning Zhang , Kihwan Kim

The simulation of the two-dimensional Ising model is used as a benchmark to show the computational capabilities of Graphic Processing Units (GPUs). The rich programming environment now available on GPUs and flexible hardware capabilities…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-26 Joshua Romero , Mauro Bisson , Massimiliano Fatica , Massimo Bernaschi

Quantum annealing is getting increasing attention in combinatorial optimization. The quantum processing unit by D-Wave is constructed to approximately solve Ising models on so-called Chimera graphs. Ising models are equivalent to quadratic…

Data Structures and Algorithms · Computer Science 2019-04-30 Michael Juenger , Elisabeth Lobe , Petra Mutzel , Gerhard Reinelt , Franz Rendl , Giovanni Rinaldi , Tobias Stollenwerk

The nearing end of Moore's Law has been driving the development of domain-specific hardware tailored to solve a special set of problems. Along these lines, probabilistic computing with inherently stochastic building blocks (p-bits) have…

Hardware Architecture · Computer Science 2022-11-23 Navid Anjum Aadit , Andrea Grimaldi , Giovanni Finocchio , Kerem Y. Camsari

The emergence of specialized optimization hardware such as CMOS annealers and adiabatic quantum computers carries the promise of solving hard combinatorial optimization problems more efficiently in hardware. Recent work has focused on…

Machine Learning · Computer Science 2020-03-05 Eldan Cohen , Avradip Mandal , Hayato Ushijima-Mwesigwa , Arnab Roy

Ising machines as hardware solvers of combinatorial optimization problems (COPs) can efficiently explore large solution spaces due to their inherent parallelism and physics-based dynamics. Many important COP classes such as satisfiability…

Coherent Ising Machines (CIMs) have emerged as a hybrid form of quantum computing devices designed to solve NP-complete problems, offering an exciting opportunity for discovering optimal solutions. Despite challenges such as susceptibility…

Advances in artificial intelligence (AI) and deep learning have raised concerns about its increasing energy consumption, while demand for deploying AI in mobile devices and machines at the edge is growing. Binary neural networks (BNNs) have…

Optimization and Control · Mathematics 2026-01-05 Jonas Christoffer Villumsen , Yusuke Sugita

The Quadratic Unconstrained Binary Optimization problem (QUBO) has become a unifying model for representing a wide range of combinatorial optimization problems, and for linking a variety of disciplines that face these problems. A new class…

Artificial Intelligence · Computer Science 2017-05-30 Mark Lewis , Fred Glover

Ising annealer is a promising quantum-inspired computing architecture for combinatorial optimization problems. In this paper, we introduce an Ising annealer based on the Hamiltonian Monte Carlo, which updates the variables of all dimensions…

Quantum Physics · Physics 2025-01-15 Hao Wang , Zixuan Liu , Zhixin Xie , Langyu Li , Zibo Miao , Wei Cui , Yu Pan

Topology optimization is an essential tool in computational engineering, for example, to improve the design and efficiency of flow channels. At the same time, Ising machines, including digital or quantum annealers, have been used as…

Computational Engineering, Finance, and Science · Computer Science 2024-11-14 Yudai Suzuki , Shiori Aoki , Fabian Key , Katsuhiro Endo , Yoshiki Matsuda , Shu Tanaka , Marek Behr , Mayu Muramatsu

Computationally hard combinatorial optimization problems are pervasive in science and engineering, yet their NP-hard nature renders them increasingly inefficient to solve on conventional von Neumann architectures as problem size grows.…

Emerging Technologies · Computer Science 2025-12-22 Yu Qian , Alptekin Vardar , Konrad Seidel , David Lehninger , Maximilian Lederer , Zhiguo Shi , Cheng Zhuo , Kai Ni , Thomas Kämpfe , Xunzhao Yin

The ultimate goal of any sparse coding method is to accurately recover from a few noisy linear measurements, an unknown sparse vector. Unfortunately, this estimation problem is NP-hard in general, and it is therefore always approached with…

Quantum computing has emerged as a promising alternative for solving combinatorial optimization problems. The standard approach for encoding optimization problems on quantum processing units (QPUs) involves transforming them into their…

Emerging Technologies · Computer Science 2025-10-15 Meerzhan Kanatbekova , Vincenzo De Maio , Ivona Brandic

Optimizing objective functions stands to benefit significantly from leveraging quantum computers, promising enhanced solution quality across various application domains in the future. However, harnessing the potential of quantum solvers…

Quantum Physics · Physics 2025-10-15 Deborah Volpe , Nils Quetschlich , Mariagrazia Graziano , Giovanna Turvani , Robert Wille
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