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Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

Vocabulary-free fine-grained image recognition aims to distinguish visually similar categories within a meta-class without a fixed, human-defined label set. Existing solutions for this problem are limited by either the usage of a large and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Dmitry Demidov , Zaigham Zaheer , Zongyan Han , Omkar Thawakar , Rao Anwer

The paradigm shift from item-centric ranking to answer-centric synthesis is redefining the role of search engines. While recent industrial progress has applied generative techniques to closed-set item ranking in e-commerce, research and…

Computation and Language · Computer Science 2026-03-12 Wei Wu , Peilun Zhou , Liyi Chen , Qimeng Wang , Chengqiang Lu , Yan Gao , Yi Wu , Yao Hu , Hui Xiong

Recent studies increasingly explore Large Language Models (LLMs) as a new paradigm for recommendation systems due to their scalability and world knowledge. However, existing work has three key limitations: (1) most efforts focus on…

Recently, large language models (LLMs) have exhibited significant progress in language understanding and generation. By leveraging textual features, customized LLMs are also applied for recommendation and demonstrate improvements across…

Information Retrieval · Computer Science 2023-11-07 Zhenrui Yue , Sara Rabhi , Gabriel de Souza Pereira Moreira , Dong Wang , Even Oldridge

Drug-drug interaction event (DDIE) prediction is crucial for preventing adverse reactions and ensuring optimal therapeutic outcomes. However, existing methods often face challenges with imbalanced datasets, complex interaction mechanisms,…

Machine Learning · Computer Science 2026-03-16 Pengfei Liu , Jun Tao , Zhixiang Ren

Personalized medication planning involves selecting medications and determining a dosing schedule to achieve medical goals specific to each individual patient. Previous work successfully demonstrated that automated planners, using general…

Artificial Intelligence · Computer Science 2026-01-08 Yonatan Vernik , Alexander Tuisov , David Izhaki , Hana Weitman , Gal A. Kaminka , Alexander Shleyfman

Large language models (LLMs) offer substantial promise for text classification in political science, yet their effectiveness often depends on high-quality prompts and exemplars. To address this, we introduce a three-stage framework that…

Computation and Language · Computer Science 2025-04-08 Menglin Liu , Ge Shi

Traditional Chinese Medicine (TCM) presents a rich and structurally unique knowledge system that challenges conventional applications of large language models (LLMs). Although previous TCM-specific LLMs have shown progress through…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Shuai Zeng , Yang Yu , Xiaoting Tang , Guanghui An , Dong Xu

In this work, we introduce FLAME, a family of extremely lightweight and capable Time Series Foundation Models, which support both deterministic and probabilistic forecasting via generative probabilistic modeling, thus ensuring both…

Machine Learning · Computer Science 2026-02-10 Xingjian Wu , Hanyin Cheng , Xiangfei Qiu , Zhengyu Li , Jilin Hu , Chenjuan Guo , Bin Yang

Classification is an important topic in statistics and machine learning with great potential in many real applications. In this paper, we investigate two popular large margin classification methods, Support Vector Machine (SVM) and Distance…

Machine Learning · Statistics 2013-10-14 Xingye Qiao , Lingsong Zhang

Traditional recommendation algorithms are not designed to provide personalized recommendations based on user preferences provided through text, e.g., "I enjoy light-hearted comedies with a lot of humor". Large Language Models (LLMs) have…

Information Retrieval · Computer Science 2025-07-11 Aaron Goldstein , Ayan Dutta

Explainable recommender systems are designed to elucidate the explanation behind each recommendation, enabling users to comprehend the underlying logic. Previous works perform rating prediction and explanation generation in a multi-task…

Information Retrieval · Computer Science 2025-04-09 Shijie Liu , Ruixing Ding , Weihai Lu , Jun Wang , Mo Yu , Xiaoming Shi , Wei Zhang

Aligning Large Language Models (LLMs) with human values often involves balancing multiple, conflicting objectives such as helpfulness and harmlessness. Training these models is computationally intensive, and centralizing the process raises…

Machine Learning · Computer Science 2026-03-27 Fatemeh Nourzad , Amirhossein Roknilamouki , Eylem Ekici , Jia Liu , Ness Shroff

Autoregressive language models (ARMs) deliver strong likelihoods, but are inherently serial: they generate one token per forward pass, which limits throughput and inflates latency for long sequences. Diffusion Language Models (DLMs)…

Computation and Language · Computer Science 2026-04-14 Amin Karimi Monsefi , Nikhil Bhendawade , Manuel Rafael Ciosici , Dominic Culver , Yizhe Zhang , Irina Belousova

Large language models (LLMs) have recently attracted considerable interest for their ability to perform complex reasoning tasks, such as chain-of-thought (CoT) reasoning. However, most of the existing approaches to enhance this ability rely…

Computation and Language · Computer Science 2024-08-08 Xinyi Wang , Lucas Caccia , Oleksiy Ostapenko , Xingdi Yuan , William Yang Wang , Alessandro Sordoni

This study deeply explores the application of large language model (LLM) in personalized recommendation system of e-commerce. Aiming at the limitations of traditional recommendation algorithms in processing large-scale and multi-dimensional…

Information Retrieval · Computer Science 2024-10-18 Wei Xu , Jue Xiao , Jianlong Chen

Large Language Models (LLMs) have shown remarkable capabilities across various natural language processing tasks but often struggle to excel uniformly in diverse or complex domains. We propose a novel ensemble method - Diverse Fingerprint…

Machine Learning · Computer Science 2025-02-10 Seffi Cohen , Niv Goldshlager , Nurit Cohen-Inger , Bracha Shapira , Lior Rokach

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Large language models (LLMs), with advanced linguistic capabilities, have been employed in reranking tasks through a sequence-to-sequence approach. In this paradigm, multiple passages are reranked in a listwise manner and a textual reranked…

Information Retrieval · Computer Science 2024-11-08 Ruiyang Ren , Yuhao Wang , Kun Zhou , Wayne Xin Zhao , Wenjie Wang , Jing Liu , Ji-Rong Wen , Tat-Seng Chua