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The essence of precision oncology lies in its commitment to tailor targeted treatments and care measures to each patient based on the individual characteristics of the tumor. The inherent heterogeneity of tumors necessitates gathering…

Quantitative Methods · Quantitative Biology 2024-07-01 Huajun Zhou , Fengtao Zhou , Chenyu Zhao , Yingxue Xu , Luyang Luo , Hao Chen

Significant progress has been achieved in subject-driven text-to-image (T2I) generation, which aims to synthesize new images depicting target subjects according to user instructions. However, evaluating these models remains a significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Zhenyu Hu , Qing Wang , Te Cao , Luo Liao , Longfei Lu , Liqun Liu , Shuang Li , Hang Chen , Mengge Xue , Yuan Chen , Chao Deng , Peng Shu , Huan Yu , Jie Jiang

The increasing autonomy of Large Language Models (LLMs) necessitates a rigorous evaluation of their potential to aid in cyber offense. Existing benchmarks often lack real-world complexity and are thus unable to accurately assess LLMs'…

Cryptography and Security · Computer Science 2025-10-14 Zicheng Liu , Lige Huang , Jie Zhang , Dongrui Liu , Yuan Tian , Jing Shao

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Graph foundation models (GFM) aim to acquire transferable knowledge by pre-training on diverse graphs, which can be adapted to various downstream tasks. However, domain shift in graphs is inherently two-dimensional: graphs differ not only…

Computation and Language · Computer Science 2026-03-12 Xingtong Yu , Shenghua Ye , Ruijuan Liang , Chang Zhou , Hong Cheng , Xinming Zhang , Yuan Fang

Pathology is experiencing rapid digital transformation driven by whole-slide imaging and artificial intelligence (AI). While deep learning-based computational pathology has achieved notable success, traditional models primarily focus on…

Foundation models are reshaping medical imaging, yet their application in echocardiography remains limited, hindered by a heavy reliance on private datasets that prevent reproducible comparison. Echocardiography poses unique challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Darya Taratynova , Ahmed Aly , Numan Saeed , Mohammad Yaqub

Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Breast cancer is one of the leading causes of death globally, and thus there is an urgent need for early and accurate diagnostic techniques. Although ultrasound imaging is a widely used technique for breast cancer screening, it faces…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Pandiyaraju V , Shravan Venkatraman , Pavan Kumar S , Santhosh Malarvannan , Kannan A

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Tandem mass spectrometry has played a pivotal role in advancing proteomics, enabling the high-throughput analysis of protein composition in biological tissues. Many deep learning methods have been developed for \emph{de novo} peptide…

Quantitative Methods · Quantitative Biology 2024-11-01 Jingbo Zhou , Shaorong Chen , Jun Xia , Sizhe Liu , Tianze Ling , Wenjie Du , Yue Liu , Jianwei Yin , Stan Z. Li

In cross-modal retrieval tasks, such as image-to-report and report-to-image retrieval, accurately aligning medical images with relevant text reports is essential but challenging due to the inherent ambiguity and variability in medical data.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Shreyank N Gowda , Xiaobo Jin , Christian Wagner

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Pathology is the study of microscopic inspection of tissue, and a pathology diagnosis is often the medical gold standard to diagnose disease. Pathology images provide a unique challenge for computer-vision-based analysis: a single pathology…

Deep learning models have achieved high performance in medical applications, however, their adoption in clinical practice is hindered due to their black-box nature. Self-explainable models, like prototype-based models, can be especially…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Shreyasi Pathak , Jörg Schlötterer , Jeroen Veltman , Jeroen Geerdink , Maurice van Keulen , Christin Seifert

Recent advances in machine learning and large-scale biological data collections have revived the prospect of building a virtual cell, a computational model of cellular behavior that could accelerate biological discovery. One of the most…

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

In computer networking, network traffic refers to the amount of data transmitted in the form of packets between internetworked computers or Cyber-Physical Systems. Monitoring and analyzing network traffic is crucial for ensuring the…

Networking and Internet Architecture · Computer Science 2024-03-20 Chen Qian , Xiaochang Li , Qineng Wang , Gang Zhou , Huajie Shao