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The design of biological systems is hindered by uncertainty arising from both intrinsic stochasticity of biomolecular reactions and variability across laboratory or experimental conditions. In this work, we present a sequential framework to…

Machine Learning · Computer Science 2026-05-08 Michal Kobiela , Diego A. Oyarzún , Michael U. Gutmann

Bond rating Transition Probability Matrices (TPMs) are built over a one-year time-frame and for many practical purposes, like the assessment of risk in portfolios or the computation of banking Capital Requirements (e.g. the new IFRS 9…

Risk Management · Quantitative Finance 2017-10-17 Greig Smith , Goncalo dos Reis

Principal component analysis (PCA) requires the computation of a low-rank approximation to a matrix containing the data being analyzed. In many applications of PCA, the best possible accuracy of any rank-deficient approximation is at most a…

Computation · Statistics 2010-06-04 Vladimir Rokhlin , Arthur Szlam , Mark Tygert

Online prediction methods are typically presented as serial algorithms running on a single processor. However, in the age of web-scale prediction problems, it is increasingly common to encounter situations where a single processor cannot…

Machine Learning · Computer Science 2012-02-01 Ofer Dekel , Ran Gilad-Bachrach , Ohad Shamir , Lin Xiao

Predictive Coding (PC) offers a brain-inspired alternative to backpropagation for neural network training, described as a physical system minimizing its internal energy. However, in practice, PC is predominantly digitally simulated,…

Machine Learning · Computer Science 2026-02-03 Cédric Goemaere , Gaspard Oliviers , Rafal Bogacz , Thomas Demeester

Probabilistic circuits (PCs) such as sum-product networks efficiently represent large multi-variate probability distributions. They are preferred in practice over other probabilistic representations such as Bayesian and Markov networks…

Machine Learning · Computer Science 2024-02-07 Shivvrat Arya , Tahrima Rahman , Vibhav Gogate

Probabilistic circuits (PCs) are a powerful modeling framework for representing tractable probability distributions over combinatorial spaces. In machine learning and probabilistic programming, one is often interested in understanding…

Data Structures and Algorithms · Computer Science 2021-12-10 Yash Pote , Kuldeep S. Meel

Approximate model-predictive control (AMPC) aims to imitate an MPC's behavior with a neural network, removing the need to solve an expensive optimization problem at runtime. However, during deployment, the parameters of the underlying MPC…

Parameter-efficient fine-tuning (PEFT) has become a popular way to adapt large pre-trained models to new tasks. Most PEFT methods update only a small subset of parameters while freezing the rest, avoiding redundant computation. As they…

Machine Learning · Computer Science 2025-08-25 Sungmin Kang , Jisoo Kim , Salman Avestimehr , Sunwoo Lee

Model Predictive Control (MPC) is an optimal control algorithm with strong stability and robustness guarantees. Despite its popularity in robotics and industrial applications, the main challenge in deploying MPC is its high computation…

Systems and Control · Electrical Eng. & Systems 2024-12-31 Camilo Gonzalez , Houshyar Asadi , Lars Kooijman , Chee Peng Lim

Probabilistic circuits (PCs) are a class of tractable probabilistic models that allow efficient, often linear-time, inference of queries such as marginals and most probable explanations (MPE). However, marginal MAP, which is central to many…

Artificial Intelligence · Computer Science 2022-03-07 YooJung Choi , Tal Friedman , Guy Van den Broeck

Probabilistic circuits (PCs) offer a promising avenue to perform embedded reasoning under uncertainty. They support efficient and exact computation of various probabilistic inference tasks by design. Hence, hardware-efficient computation of…

Machine Learning · Computer Science 2024-05-24 Lingyun Yao , Martin Trapp , Jelin Leslin , Gaurav Singh , Peng Zhang , Karthekeyan Periasamy , Martin Andraud

We present a novel algorithm for parameter learning in generic deep generative models that builds upon the predictive coding (PC) framework of computational neuroscience. Our approach modifies the standard PC algorithm to bring performance…

Machine Learning · Computer Science 2024-11-19 Umais Zahid , Qinghai Guo , Zafeirios Fountas

A fundamental challenge in probabilistic modeling is to balance expressivity and inference efficiency. Tractable probabilistic models (TPMs) aim to directly address this tradeoff by imposing constraints that guarantee efficient inference of…

Artificial Intelligence · Computer Science 2025-10-28 John Leland , YooJung Choi

Adaptive gradient methods have been increasingly adopted by deep learning community due to their fast convergence and reduced sensitivity to hyper-parameters. However, these methods come with limitations, such as increased memory…

Machine Learning · Computer Science 2024-12-17 Corrado Coppola , Lorenzo Papa , Irene Amerini , Laura Palagi

To solve high-dimensional parameter-dependent partial differential equations (pPDEs), a neural network architecture is presented. It is constructed to map parameters of the model data to corresponding finite element solutions. To improve…

Numerical Analysis · Mathematics 2024-03-20 Janina E. Schütte , Martin Eigel

Expectation maximization (EM) is a technique for estimating maximum-likelihood parameters of a latent variable model given observed data by alternating between taking expectations of sufficient statistics, and maximizing the expected log…

Methodology · Statistics 2018-07-10 Donna Henderson , Gerton Lunter

We present the particle stochastic approximation EM (PSAEM) algorithm for learning of dynamical systems. The method builds on the EM algorithm, an iterative procedure for maximum likelihood inference in latent variable models. By combining…

Computation · Statistics 2019-12-11 Andreas Lindholm , Fredrik Lindsten

Parameter estimation in logistic regression is a well-studied problem with the Newton-Raphson method being one of the most prominent optimization techniques used in practice. A number of monotone optimization methods including…

Computation · Statistics 2023-04-11 Nicholas C. Henderson , Zhongzhe Ouyang

Convex regression is a promising area for bridging statistical estimation and deterministic convex optimization. New piecewise linear convex regression methods are fast and scalable, but can have instability when used to approximate…

Machine Learning · Computer Science 2012-06-22 Lauren Hannah , David Dunson