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Structured illumination microscopy (SIM) has emerged as an essential technique for 3D and live-cell super-resolution imaging. However, to date, there has not been a dedicated workshop or journal issue covering the various aspects of SIM,…

Wide-field fluorescence microscopy, while much faster than confocal microscopy, suffers from a lack of optical sectioning and poor axial resolution. 3D structured illumination microscopy (SIM) has been demonstrated to provide optical…

This paper presents, for the first time, an image enhancement methodology designed to enhance the clarity of small intestinal villi in Wireless Capsule Endoscopy (WCE) images. This method first separates the low-frequency and high-frequency…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Shaojie Zhang , Yinghui Wang , Peixuan Liu , Yukai Wang , Liangyi Huang , Mingfeng Wang , Ibragim. Atadjanov

Structured illumination microscopy (SIM) achieves superresolution in fluorescence imaging through patterned illumination and computational image reconstruction, yet current methods require bulky, costly modulation optics and high-precision…

Optics · Physics 2024-04-15 Tamal Roy , Peter T. Brown , Douglas P. Shepherd , Lisa V. Poulikakos

This thesis centres on the development of multidimensional fluorescence imaging tools, with a particular emphasis on fluorescence lifetime imaging (FLIM) microscopy for application to biological research. The key aspects of this thesis are…

Instrumentation and Detectors · Physics 2017-08-14 Egidijus Auksorius

The microwave imaging system(MIS) stands out among prominent imaging tools for capturing images of concealed obstacles. Leveraging its capability to penetrate through heterogeneous environments MIS has been widely used for subsurface…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Mohammad Ramezaninia , Mohammad Zoofaghari

Intensity correlation microscopy (ICM), which is prominently known through antibunching microscopy or super-resolution optical fluctuation imaging (SOFI), provides superresolution through a correlation analysis of antibunching of…

Optics · Physics 2018-10-08 Anton Classen , Joachim von Zanthier , Girish S. Agarwal

Structured illumination microscopy (SIM) has emerged as a widely adopted super-resolution fluorescence imaging modality, offering high speed, low phototoxicity, large field-of-view, and compatibility with conventional probes. However, when…

Image and Video Processing · Electrical Eng. & Systems 2026-03-19 Jiaming Qian , Jing Feng , Hongjun Wu , Maoxian Zhang , Dongqin Lu , Tianchi Kang , Xinyu Han , Qian Chen , Chao Zuo

The dynamic architecture of the microtubule cytoskeleton is crucial for cell division, motility and morphogenesis. The dynamic properties of microtubules - growth, shrinkage, nucleation and severing - are regulated by an arsenal of…

Quantitative Methods · Quantitative Biology 2021-07-06 Yin-wei Kuo , Jonathon Howard

Simultaneous identification and metabolic analysis of microbes with single-cell resolution and high throughput is necessary to answer the question of "who eats what, when, and where" in complex microbial communities. Here, we present a…

Biological Physics · Physics 2022-09-13 Yeran Bai , Zhongyue Guo , Fátima C. Pereira , Michael Wagner , Ji-Xin Cheng

We present a fast, high-throughput method for characterizing the motility of microorganisms in 3D based on standard imaging microscopy. Instead of tracking individual cells, we analyse the spatio-temporal fluctuations of the intensity in…

Structured illumination microscopy (SIM) provides images of fluorescent objects at an enhanced resolution greater than that of conventional epifluorescence wide-field microscopy. Initially demonstrated in 1999 to enhance the lateral…

Optics · Physics 2022-03-09 James D. Manton

Lightsheet microscopy is a powerful 3-D imaging technique that addresses limitations of traditional optical and confocal microscopy but suffers from a low penetration depth and reduced image quality at greater depths. Multiview lightsheet…

Image and Video Processing · Electrical Eng. & Systems 2025-03-21 Marek Wodzinski , Henning Müller

Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical information for clinical diagnosis and evaluation of a broad-spectrum of pathologies. Recently, the emergence of super-resolution ultrasound…

Fish diseases in aquaculture constitute a significant hazard to nutriment security. Identification of infected fishes in aquaculture remains challenging to find out at the early stage due to the dearth of necessary infrastructure. The…

Computer Vision and Pattern Recognition · Computer Science 2021-05-11 Md Shoaib Ahmed , Tanjim Taharat Aurpa , Md. Abul Kalam Azad

Selective plane illumination microscopy (SPIM), or light sheet, is a powerful three-dimensional imaging approach. However, access to and interfacing microscopes with microfluidics have remained challenging. Complex interfacing with…

Biological Physics · Physics 2023-09-18 Per Niklas Hedde , Erika L. Gomez , Leora Duong , Robert E. Steele , Siavash Ahrar

Table-top extreme ultraviolet (EUV) microscopy offers unique opportunities for label-free investigation of biological samples. Here, we demonstrate ptychographic EUV imaging of two dried, unstained model specimens: germlings of a fungus…

Nonlinear structured illumination microscopy (nSIM) is an effective approach for super-resolution wide-field fluorescence microscopy with a theoretically unlimited resolution. In nSIM, carefully designed, highly-contrasted illumination…

Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…

Quantitative Methods · Quantitative Biology 2012-02-03 Juliane Liepe , Federico Felizzi , Agata Pernus , Maria Hanulova

Microscopes are essential for biomechanics and hydrodynamical investigation of small aquatic organisms. We report a DIY microscope (GLUBscope) that enables the visualization of organisms from two orthogonal imaging planes (top and side…

Quantitative Methods · Quantitative Biology 2023-07-26 Brian T. Le , Katherine M. Auer , David A. Lopez , Justin P. Shum , Brian Suarsana , Ga-Young Kelly Suh , Per Niklas Hedde , Siavash Ahrar