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Deep learning has made significant advancements in supervised learning. However, models trained in this setting often face challenges due to domain shift between training and test sets, resulting in a significant drop in performance during…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Lei Qi , Hongpeng Yang , Yinghuan Shi , Xin Geng

Medical image understanding requires meticulous examination of fine visual details, with particular regions requiring additional attention. While radiologists build such expertise over years of experience, it is challenging for AI models to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Ying Jin , Zhuoran Zhou , Haoquan Fang , Jenq-Neng Hwang

Single-source domain generalization (SDG) in medical image segmentation is a challenging yet essential task as domain shifts are quite common among clinical image datasets. Previous attempts most conduct global-only/random augmentation.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Jie Sun , Kaizhu Huang

Single-source domain generalization (SDG) aims to learn a model from a single source domain that can generalize well on unseen target domains. This is an important task in computer vision, particularly relevant to medical imaging where…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Boqi Chen , Yuanzhi Zhu , Yunke Ao , Sebastiano Caprara , Reto Sutter , Gunnar Rätsch , Ender Konukoglu , Anna Susmelj

Deep learning-based medical image segmentation faces significant challenges arising from limited labeled data and domain shifts. While prior approaches have primarily addressed these issues independently, their simultaneous occurrence is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zanting Ye , Ke Wang , Wenbing Lv , Qianjin Feng , Lijun Lu

Convolutional neural networks have been widely applied to medical image segmentation and have achieved considerable performance. However, the performance may be significantly affected by the domain gap between training data (source domain)…

Image and Video Processing · Electrical Eng. & Systems 2022-07-28 Junyan Lyu , Yiqi Zhang , Yijin Huang , Li Lin , Pujin Cheng , Xiaoying Tang

The annotation scarcity of medical image segmentation poses challenges in collecting sufficient training data for deep learning models. Specifically, models trained on limited data may not generalize well to other unseen data domains,…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Heng Li , Haojin Li , Wei Zhao , Huazhu Fu , Xiuyun Su , Yan Hu , Jiang Liu

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

Domain Generalization (DG) aims to enhance model robustness in unseen or distributionally shifted target domains through training exclusively on source domains. Although existing DG techniques, such as data manipulation, learning…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Hai Huang , Yan Xia , Sashuai Zhou , Hanting Wang , Shulei Wang , Zhou Zhao

Machine learning models are intrinsically vulnerable to domain shift between training and testing data, resulting in poor performance in novel domains. Domain generalization (DG) aims to overcome the problem by leveraging multiple source…

Computer Vision and Pattern Recognition · Computer Science 2022-10-27 Tingwei Wang , Da Li , Kaiyang Zhou , Tao Xiang , Yi-Zhe Song

Domain Generalization (DG) aims to reduce domain shifts between domains to achieve promising performance on the unseen target domain, which has been widely practiced in medical image segmentation. Single-source domain generalization (SDG)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Hanhui Wang , Huaize Ye , Yi Xia , Xueyan Zhang

The field of medical image segmentation is challenged by domain generalization (DG) due to domain shifts in clinical datasets. The DG challenge is exacerbated by the scarcity of medical data and privacy concerns. Traditional single-source…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Qiang Qiao , Wenyu Wang , Meixia Qu , Kun Su , Bin Jiang , Qiang Guo

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

Deep learning models often encounter challenges in making accurate inferences when there are domain shifts between the source and target data. This issue is particularly pronounced in clinical settings due to the scarcity of annotated data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Heng Li , Haojin Li , Jianyu Chen , Mingyang Ou , Hai Shu , Heng Miao

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

Machine learning models typically suffer from the domain shift problem when trained on a source dataset and evaluated on a target dataset of different distribution. To overcome this problem, domain generalisation (DG) methods aim to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Kaiyang Zhou , Yongxin Yang , Timothy Hospedales , Tao Xiang

Medical imaging datasets usually exhibit domain shift due to the variations of scanner vendors, imaging protocols, etc. This raises the concern about the generalization capacity of machine learning models. Domain generalization (DG), which…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Chenxin Li , Qi Qi , Xinghao Ding , Yue Huang , Dong Liang , Yizhou Yu

Federated domain generalization aims to train a global model from multiple source domains and ensure its generalization ability to unseen target domains. Due to the target domain being with unknown domain shifts, attempting to approximate…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Haoxuan Che , Yifei Wu , Haibo Jin , Yong Xia , Hao Chen
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