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Despite significant advancements in Large Language Models (LLMs) and Large Vision-Language Models (LVLMs), current models still face substantial challenges in handling complex, multi-turn, and visually-grounded tasks that demand deep…

Computation and Language · Computer Science 2025-08-22 Seungmin Han , Haeun Kwon , Ji-jun Park , Taeyang Yoon

The discovery of novel small molecule drugs remains a critical scientific challenge with far-reaching implications for treating diseases and advancing human health. Traditional drug development--especially for small molecule…

Biomolecules · Quantitative Biology 2025-04-01 Bowen Gao , Yanwen Huang , Yiqiao Liu , Wenxuan Xie , Wei-Ying Ma , Ya-Qin Zhang , Yanyan Lan

The development of autonomous web agents, powered by Large Language Models (LLMs) and reinforcement learning (RL), represents a significant step towards general-purpose AI assistants. However, training these agents is severely hampered by…

Computation and Language · Computer Science 2026-04-21 Hang Ding , Peidong Liu , Junqiao Wang , Ziwei Ji , Meng Cao , Rongzhao Zhang , Lynn Ai , Eric Yang , Tianyu Shi , Lei Yu

Large Language Models (LLMs) have become increasingly integral to enhancing developer productivity, particularly in code generation, comprehension, and repair tasks. However, fine-tuning these models with high-quality, real-world data is…

Software Engineering · Computer Science 2024-12-12 Xiaoyun Liang , Jingyi Ren , Jiayi Qi , Chao Peng , Bo Jiang

Large Language Models (LLMs) trained with reinforcement learning and verifiable rewards have achieved strong results on complex reasoning tasks. Recent work extends this paradigm to a multi-agent setting, where a meta-thinking agent…

Artificial Intelligence · Computer Science 2025-11-05 Zhiwei Zhang , Xiaomin Li , Yudi Lin , Hui Liu , Ramraj Chandradevan , Linlin Wu , Minhua Lin , Fali Wang , Xianfeng Tang , Qi He , Suhang Wang

Reinforcement learning (RL) algorithms have been around for decades and employed to solve various sequential decision-making problems. These algorithms however have faced great challenges when dealing with high-dimensional environments. The…

Machine Learning · Computer Science 2020-04-01 Thanh Thi Nguyen , Ngoc Duy Nguyen , Saeid Nahavandi

Graphical User Interface (GUI) agents, driven by Multi-modal Large Language Models (MLLMs), have emerged as a promising paradigm for enabling intelligent interaction with digital systems. This paper provides a structured survey of recent…

Artificial Intelligence · Computer Science 2025-05-14 Jiahao Li , Kaer Huang

This study presents the LLM-Agent-Controller, a multi-agent large language model (LLM) system developed to address a wide range of problems in control engineering (Control Theory). The system integrates a central controller agent with…

Artificial Intelligence · Computer Science 2025-05-27 Rasoul Zahedifar , Sayyed Ali Mirghasemi , Mahdieh Soleymani Baghshah , Alireza Taheri

Autonomous driving has made significant strides through data-driven techniques, achieving robust performance in standardized tasks. However, existing methods frequently overlook user-specific preferences, offering limited scope for…

Robotics · Computer Science 2025-05-13 Chengkai Xu , Jiaqi Liu , Yicheng Guo , Yuhang Zhang , Peng Hang , Jian Sun

Large Language Models (LLMs), enhanced through agent tuning, have demonstrated remarkable capabilities in Chain-of-Thought (CoT) and tool utilization, significantly surpassing the performance of standalone models. However, the multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Tianhong Gao , Yannian Fu , Weiqun Wu , Haixiao Yue , Shanshan Liu , Gang Zhang

There has been a growing interest in developing learner models to enhance learning and teaching experiences in educational environments. However, existing works have primarily focused on structured environments relying on meticulously…

Machine Learning · Computer Science 2024-05-01 Bahar Radmehr , Adish Singla , Tanja Käser

Reinforcement Learning (RL) enables an intelligent agent to optimise its performance in a task by continuously taking action from an observed state and receiving a feedback from the environment in form of rewards. RL typically uses tables…

Artificial Intelligence · Computer Science 2025-01-28 Alberto Castagna

Clinical decision-making is a dynamic, interactive, and cyclic process where doctors have to repeatedly decide on which clinical action to perform and consider newly uncovered information for diagnosis and treatment. Large Language Models…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Ege Özsoy , Nassir Navab , Matthias Keicher

Large language models (LLMs) have achieved significant success in interacting with human. However, recent studies have revealed that these models often suffer from hallucinations, leading to overly confident but incorrect judgments. This…

Computation and Language · Computer Science 2023-09-06 Yusheng Liao , Yutong Meng , Hongcheng Liu , Yanfeng Wang , Yu Wang

While Large Language Model (LLM) agents show promise in automated trading, they still face critical limitations. Prominent multi-agent frameworks often suffer from inefficiency, produce inconsistent signals, and lack the end-to-end…

Computational Engineering, Finance, and Science · Computer Science 2026-04-21 Zheye Deng , Weixiang Yan , Changlong Yu , Jiashu Wang

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Large language models (LLMs) have shown great potential in the medical domain. However, existing models still fall short when faced with complex medical diagnosis task in the real world. This is mainly because they lack sufficient reasoning…

Artificial Intelligence · Computer Science 2025-08-06 Qi Peng , Jialin Cui , Jiayuan Xie , Yi Cai , Qing Li

Document Question Answering (DocQA) is a very common task. Existing methods using Large Language Models (LLMs) or Large Vision Language Models (LVLMs) and Retrieval Augmented Generation (RAG) often prioritize information from a single…

Machine Learning · Computer Science 2025-03-19 Siwei Han , Peng Xia , Ruiyi Zhang , Tong Sun , Yun Li , Hongtu Zhu , Huaxiu Yao

Large language models (LLMs) encode a vast amount of world knowledge acquired from massive text datasets. Recent studies have demonstrated that LLMs can assist an embodied agent in solving complex sequential decision making tasks by…

Artificial Intelligence · Computer Science 2024-06-27 Bin Hu , Chenyang Zhao , Pu Zhang , Zihao Zhou , Yuanhang Yang , Zenglin Xu , Bin Liu

Open-domain dialogue systems have seen remarkable advancements with the development of large language models (LLMs). Nonetheless, most existing dialogue systems predominantly focus on brief single-session interactions, neglecting the…

Computation and Language · Computer Science 2025-02-14 Hao Li , Chenghao Yang , An Zhang , Yang Deng , Xiang Wang , Tat-Seng Chua