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Myocardial infarction significantly degrades heart function, and current treatments can bring forth serious cost and complications including blood clots and infections. To improve the current state of treatment, researchers are developing…

In the framework of accurate and efficient segregated schemes for 3D cardiac electromechanics and 0D cardiovascular models, we propose here a novel numerical approach to address the coupled 3D-0D problem introduced in Part I of this…

Understanding the biomechanics of the heart in health and disease plays an important role in the diagnosis and treatment of heart failure. The use of computational biomechanical models for therapy assessment is paving the way for…

Finite element simulations are an enticing tool to evaluate heart valve function in healthy and diseased patients; however, patient-specific simulations derived from 3D echocardiography are hampered by several technical challenges. In this…

Total endovascular repair of the aortic arch represents a promising option for patients ineligible to open surgery. Custom-made design of stent-grafts (SG), such as the Terumo Aortic RelayBranch device (DB), requires complex preoperative…

Medical Physics · Physics 2019-02-11 L. Derycke , D. Perrin , F. Cochennec , J. -N. Albertini , S. Avril

This study evaluates the fluid dynamics inside and outside transcatheter blood pump positioned in the aorta. We focus on the pump's impact on blood component damage and arterial wall stress. CFD simulations were performed for rotational…

Fluid Dynamics · Physics 2025-03-03 Yeojin Park , Osman Aycan , Lyes Kadem

We present a methodology to simulate the mechanics of knots in elastic rods using geometrically nonlinear, full three-dimensional (3D) finite element analysis. We focus on the mechanical behavior of knots in tight configurations, for which…

Soft Condensed Matter · Physics 2021-02-03 Changyeob Baek , Paul Johanns , Tomohiko G. Sano , Paul Grandgeorge , Pedro M. Reis

The success of embolisation, a minimally invasive treatment of liver cancer, could be evaluated in the operational room with cone-beam CT by acquiring a dynamic perfusion scan. The reconstruction algorithm must address the issues of low…

This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with…

Tissues and Organs · Quantitative Biology 2021-10-15 Alexander D. Kaiser , Rohan Shad , William Hiesinger , Alison L. Marsden

We consider the common problem setting of an elastic sphere impacting on a flexible beam. In contrast to previous studies, we analyze the modal energy distribution induced by the impact, having in mind the particular application of impact…

Systems and Control · Electrical Eng. & Systems 2022-07-05 Felix Gehr , Timo Theurich , Carlo Monjaraz-Tec , Johann Gross , Stefan Schwarz , Andreas Hartung , Malte Krack

Blunt traumatic aortic rupture is a heart injury that can occur in falls, automobile accidents, and sporting injuries involving impact to the thorax. Despite its severity and high morbidity rate, the research still does not provide a…

In its permanent quest of mechanobiological homeostasis, our vascula-ture significantly adapts across multiple length and time scales in various physiological and pathological conditions. Computational modeling of vascular growth and…

Medical Physics · Physics 2019-12-18 S Jamaleddin Mousavi , Solmaz Farzaneh , Stéphane Avril

Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

Fluid Dynamics · Physics 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam

Background 15 The success of cementless hip arthroplasty depends on the primary stability of the femoral stem. It remains difficult to assess the optimal number of impacts to guarantee the femoral stem stability while avoiding bone…

Purpose: Multi-expert deep learning training methods to automatically quantify ischemic brain tissue on Non-Contrast CT Materials and Methods: The data set consisted of 260 Non-Contrast CTs from 233 patients of acute ischemic stroke…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Sophie Ostmeier , Brian Axelrod , Benjamin Pulli , Benjamin F. J. Verhaaren , Abdelkader Mahammedi , Yongkai Liu , Christian Federau , Greg Zaharchuk , Jeremy J. Heit

Osteolytic metastases located in the vertebrae reduce strength and enhance the risk of vertebral fractures. This risk can be predicted by means of validated finite element models, but their reproducibility needs to be assessed. For that…

Tissues and Organs · Quantitative Biology 2025-03-24 W. Lokbani , V. Allard , T. Broussolle , CY. Barrey , C. B. Confavreux , K. Bruyere , JP. Roux , F. Bermond , H. Follet , D. Mitton

Electrical analogy (Lumped method) is an easy way to model human cardiovascular system. In this paper Lumped method is used for simulating a complete model. It describes a 36-vessel model and cardiac system of human body with details that…

Medical Physics · Physics 2014-11-21 Omid Ghasemalizadeh , Mohammad Reza Mirzaee , Bahar Firoozabadi , Kamran Hassani

Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions remain poorly understood. This study aimed to establish an…

In the present work, complex irregular bones and joints of the complete human arm were developed in a computer-aided design environment. Finite element analysis of an actual human arm was done to identify the distribution of stress using…

Tissues and Organs · Quantitative Biology 2018-07-11 Amit Kumar Bedaka , Ponnusamy Pandithevan

A numerical method is developed for solving a system of partial differential equations modeling the flow of a nematic liquid crystal fluid with stretching effect, which takes into account the geometrical shape of its molecules. This system…

Numerical Analysis · Mathematics 2016-07-11 R. C. Cabrales , F. Guillén-González , J. V. Gutiérrez-Santacreu