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As generative artificial intelligence (GenAI) becomes increasingly capable of delivering personalized learning experiences and real-time feedback, a growing number of students are incorporating these tools into their academic workflows.…

Artificial Intelligence · Computer Science 2025-12-19 Diane Myung-kyung Woodbridge , Allyson Seba , Freddie Seba , Aydin Schwartz

This master thesis describes an algorithm for automated categorization of scientific documents using deep learning techniques and compares the results to the results of existing classification algorithms. As an additional goal a reusable…

Information Retrieval · Computer Science 2017-06-20 Thomas Krause

Deep learning has been widely used in various applications from different fields such as computer vision, natural language processing, etc. However, the training models are often manually developed via many costly experiments. This manual…

Machine Learning · Computer Science 2022-11-22 Thanh Phuong Pham

Today's programmers, especially data science practitioners, make heavy use of data-processing libraries (APIs) such as PyTorch, Tensorflow, NumPy, Pandas, and the like. Program synthesizers can provide significant coding assistance to this…

Software Engineering · Computer Science 2022-05-19 Daye Nam , Baishakhi Ray , Seohyun Kim , Xianshan Qu , Satish Chandra

The rise and fall of artificial neural networks is well documented in the scientific literature of both computer science and computational chemistry. Yet almost two decades later, we are now seeing a resurgence of interest in deep learning,…

Machine Learning · Statistics 2018-08-15 Garrett B. Goh , Nathan O. Hodas , Abhinav Vishnu

We present an innovative of artificial intelligence with column chromatography, aiming to resolve inefficiencies and standardize data collection in chemical separation and purification domain. By developing an automated platform for precise…

Machine Learning · Computer Science 2024-04-16 Wenchao Wu , Hao Xu , Dongxiao Zhang , Fanyang Mo

Automated computational analysis of the vast chemical space is critical for numerous fields of research such as drug discovery and material science. Representation learning techniques have recently been employed with the primary objective…

Quantitative Methods · Quantitative Biology 2023-05-26 Atakan Yüksel , Erva Ulusoy , Atabey Ünlü , Tunca Doğan

Natural products are substances produced by organisms in nature and often possess biological activity and structural diversity. Drug development based on natural products has been common for many years. However, the intricate structures of…

Biomolecules · Quantitative Biology 2024-11-21 Koh Sakano , Kairi Furui , Masahito Ohue

Machine learning (ML) has been playing important roles in drug discovery in the past years by providing (pre-)screening tools for prioritising chemical compounds to pass through wet lab experiments. One of the main ML tasks in drug…

Biomolecules · Quantitative Biology 2025-02-25 Alex G. C. de Sá , David B. Ascher

Molecular property prediction is a crucial task that guides the design of new compounds, including drugs and materials. While explainable artificial intelligence methods aim to scrutinize model predictions by identifying influential…

Machine Learning · Computer Science 2025-08-27 Łukasz Janisiów , Marek Kochańczyk , Bartosz Zieliński , Tomasz Danel

Computational techniques are required for narrowing down the vast space of possibilities to plausible prebiotic scenarios, since precise information on the molecular composition, the dominant reaction chemistry, and the conditions for that…

Molecular Networks · Quantitative Biology 2018-02-07 Jakob L. Andersen , Christoph Flamm , Daniel Merkle , Peter F. Stadler

In this work, we apply and compare two state-of-the-art eXplainability Artificial Intelligence (XAI) methods, the Integrated Gradients (IG) and the SHapley Additive exPlanations (SHAP), that explain the fault diagnosis decisions of a highly…

In drug discovery, knowledge of the graph structure of chemical compounds is essential. Many thousands of scientific articles in chemistry and pharmaceutical sciences have investigated chemical compounds, but in cases the details of the…

Machine Learning · Statistics 2020-09-16 Martijn Oldenhof , Adam Arany , Yves Moreau , Jaak Simm

We explore the effectiveness and reliability of an artificial intelligence (AI)-based grading system for a handwritten general chemistry exam, comparing AI-assigned scores to human grading across various types of questions. Exam pages and…

Computers and Society · Computer Science 2025-11-11 Jan Cvengros , Gerd Kortemeyer

Artificial intelligence (AI) in the form of deep learning bears promise for drug discovery and chemical biology, $\textit{e.g.}$, to predict protein structure and molecular bioactivity, plan organic synthesis, and design molecules…

Biomolecules · Quantitative Biology 2022-12-29 Rıza Özçelik , Derek van Tilborg , José Jiménez-Luna , Francesca Grisoni

Descriptor generation methods using latent representations of encoder$-$decoder (ED) models with SMILES as input are useful because of the continuity of descriptor and restorability to the structure. However, it is not clear how the…

Chemical Physics · Physics 2023-04-14 Shumpei Nemoto , Tadahaya Mizuno , Hiroyuki Kusuhara

Classification of proteins based on their structure provides a valuable resource for studying protein structure, function and evolutionary relationships. With the rapidly increasing number of known protein structures, manual and…

Computational Engineering, Finance, and Science · Computer Science 2009-07-14 Oktie Hassanzadeh

While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

In recent years, conventional chemistry techniques have faced significant challenges due to their inherent limitations, struggling to cope with the increasing complexity and volume of data generated in contemporary research endeavors.…