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The need for high-quality automated seizure detection algorithms based on electroencephalography (EEG) becomes ever more pressing with the increasing use of ambulatory and long-term EEG monitoring. Heterogeneity in validation methods of…

Electroencephalogram (EEG) is an important diagnostic test that physicians use to record brain activity and detect seizures by monitoring the signals. There have been several attempts to detect seizures and abnormalities in EEG signals with…

Machine Learning · Computer Science 2022-03-22 Kwanhyung Lee , Hyewon Jeong , Seyun Kim , Donghwa Yang , Hoon-Chul Kang , Edward Choi

The evaluation of machine learning algorithms in biomedical fields for applications involving sequential data lacks standardization. Common quantitative scalar evaluation metrics such as sensitivity and specificity can often be misleading…

Machine Learning · Computer Science 2019-12-03 Saeedeh Ziyabari , Vinit Shah , Meysam Golmohammadi , Iyad Obeid , Joseph Picone

Reliable seizure detection is critical for diagnosing and managing epilepsy, yet clinical workflows remain dependent on time-consuming manual EEG interpretation. While machine learning has shown promise, existing approaches often rely on…

Machine Learning · Computer Science 2025-08-12 Bartlomiej Chybowski , Shima Abdullateef , Hollan Haule , Alfredo Gonzalez-Sulser , Javier Escudero

Machine learning algorithms for seizure detection have shown considerable diagnostic potential, with recent reported accuracies reaching 100%. Yet, only few published algorithms have fully addressed the requirements for successful clinical…

Signal Processing · Electrical Eng. & Systems 2024-08-15 Nina Moutonnet , Steven White , Benjamin P Campbell , Saeid Sanei , Toshihisa Tanaka , Hong Ji , Danilo Mandic , Gregory Scott

Electroencephalogram (EEG) monitoring and objective seizure identification is an essential clinical investigation for some patients with epilepsy. Accurate annotation is done through a time-consuming process by EEG specialists.…

Medical Physics · Physics 2021-04-22 Yikai Yang , Nhan Duy Truong , Christina Maher , Armin Nikpour , Omid Kavehei

In current clinical practice, electroencephalograms (EEG) are reviewed and analyzed by well-trained neurologists to provide supports for therapeutic decisions. The way of manual reviewing is labor-intensive and error prone. Automatic and…

Signal Processing · Electrical Eng. & Systems 2019-06-07 Xinghua Yao , Qiang Cheng , Guo-Qiang Zhang

Machine learning (ML)-based analysis of electroencephalograms (EEGs) is playing an important role in advancing neurological care. However, the difficulties in automatically extracting useful metadata from clinical records hinder the…

Computation and Language · Computer Science 2021-09-14 Samarth Rawal , Yogatheesan Varatharajah

Automated seizure detection using clinical electroencephalograms is a challenging machine learning problem because the multichannel signal often has an extremely low signal to noise ratio. Events of interest such as seizures are easily…

Machine Learning · Computer Science 2017-12-29 Meysam Golmohammadi , Saeedeh Ziyabari , Vinit Shah , Silvia Lopez de Diego , Iyad Obeid , Joseph Picone

Neonatal seizure detection algorithms (SDA) are approaching the benchmark of human expert annotation. Measures of algorithm generalizability and non-inferiority as well as measures of clinical efficacy are needed to assess the full scope of…

Machine Learning · Computer Science 2022-02-25 Karoliina T. Tapani , Päivi Nevalainen , Sampsa Vanhatalo , Nathan J. Stevenson

Accurate classification of seizure types plays a crucial role in the treatment and disease management of epileptic patients. Epileptic seizure types not only impact the choice of drugs but also the range of activities a patient can safely…

Machine Learning · Computer Science 2020-08-13 Subhrajit Roy , Umar Asif , Jianbin Tang , Stefan Harrer

Since the manual detection of electrographic seizures in continuous electroencephalogram (EEG) monitoring is very time-consuming and requires a trained expert, attempts to develop automatic seizure detection are diverse and ongoing. Machine…

Signal Processing · Electrical Eng. & Systems 2019-08-02 Poomipat Boonyakitanont , Apiwat Lek-uthai , Krisnachai Chomtho , Jitkomut Songsiri

One of epileptology's fundamental aims is the formulation of a universal, internally consistent seizure definition. To assess this aim's feasibility, three signal analysis methods were applied to a seizure time series and performance…

Neurons and Cognition · Quantitative Biology 2011-11-15 Ivan Osorio , Alexey Lyubushin , Didier Sornette

Purpose: Understanding fluctuations of seizure severity within individuals is important for defining treatment outcomes and response to therapy, as well as developing novel treatments for epilepsy. Current methods for grading seizure…

A deep learning classifier for detecting seizures in neonates is proposed. This architecture is designed to detect seizure events from raw electroencephalogram (EEG) signals as opposed to the state-of-the-art hand engineered feature-based…

Machine Learning · Computer Science 2021-05-31 Alison O'Shea , Gordon Lightbody , Geraldine Boylan , Andriy Temko

Automated seizure detection and classification from electroencephalography (EEG) can greatly improve seizure diagnosis and treatment. However, several modeling challenges remain unaddressed in prior automated seizure detection and…

Signal Processing · Electrical Eng. & Systems 2022-03-15 Siyi Tang , Jared A. Dunnmon , Khaled Saab , Xuan Zhang , Qianying Huang , Florian Dubost , Daniel L. Rubin , Christopher Lee-Messer

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Epilepsy is one of the most prevalent brain disorders that disrupts the lives of millions worldwide. For patients with drug-resistant seizures, there exist implantable devices capable of monitoring neural activity, promptly triggering…

Signal Processing · Electrical Eng. & Systems 2023-10-31 Arman Zarei , Bingzhao Zhu , Mahsa Shoaran

The lack of standardization in seizure forecasting slows progress in the field and limits the clinical translation of forecasting models. In this work, we introduce a Python-based framework aimed at streamlining the development, assessment,…

Quantitative Methods · Quantitative Biology 2025-10-14 Ana Sofia Carmo , Lourenço Abrunhosa Rodrigues , Ana Rita Peralta , Ana Fred , Carla Bentes , Hugo Plácido da Silva

Automatic classification of epileptic seizure types in electroencephalograms (EEGs) data can enable more precise diagnosis and efficient management of the disease. This task is challenging due to factors such as low signal-to-noise ratios,…

Machine Learning · Computer Science 2020-10-01 Umar Asif , Subhrajit Roy , Jianbin Tang , Stefan Harrer
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