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Estimating the conditional average treatment effect (CATE) from observational data is relevant for many applications such as personalized medicine. Here, we focus on the widespread setting where the observational data come from multiple…

Machine Learning · Computer Science 2024-06-05 Jonas Schweisthal , Dennis Frauen , Mihaela van der Schaar , Stefan Feuerriegel

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects…

Methodology · Statistics 2024-04-23 Kosuke Imai , Michael Lingzhi Li

Many decision-making problems require ranking individuals by their treatment effects rather than estimating the exact effect magnitudes. Examples include prioritizing patients for preventive care interventions, or ranking customers by the…

Machine Learning · Computer Science 2026-05-27 Henri Arno , Dennis Frauen , Emil Javurek , Thomas Demeester , Stefan Feuerriegel

Estimating heterogeneous treatment effects is important to tailor treatments to those individuals who would most likely benefit. However, conditional average treatment effect predictors may often be trained on one population but possibly…

Machine Learning · Computer Science 2024-10-18 Christoph Kern , Michael Kim , Angela Zhou

Identifying bio-signals based-sleep stages requires time-consuming and tedious labor of skilled clinicians. Deep learning approaches have been introduced in order to challenge the automatic sleep stage classification conundrum. However, the…

Causal mediation analysis aims at disentangling a treatment effect into an indirect mechanism operating through an intermediate outcome or mediator, as well as the direct effect of the treatment on the outcome of interest. However, the…

Econometrics · Economics 2020-05-05 Martin Huber , Lukáš Lafférs

Estimation of heterogeneous treatment effects is an active area of research. Most of the existing methods, however, focus on estimating the conditional average treatment effects of a single, binary treatment given a set of pre-treatment…

Methodology · Statistics 2025-05-30 Max Goplerud , Kosuke Imai , Nicole E. Pashley

Estimating how a treatment affects different individuals, known as heterogeneous treatment effect estimation, is an important problem in empirical sciences. In the last few years, there has been a considerable interest in adapting machine…

Machine Learning · Computer Science 2024-10-18 Christopher Tran , Keith Burghardt , Kristina Lerman , Elena Zheleva

We address a core problem in causal inference: estimating heterogeneous treatment effects using panel data with general treatment patterns. Many existing methods either do not utilize the potential underlying structure in panel data or have…

Machine Learning · Statistics 2024-06-11 Retsef Levi , Elisabeth Paulson , Georgia Perakis , Emily Zhang

In observational settings where treatment and outcome share unmeasured confounders but an observed mediator remains unconfounded, the front-door (FD) adjustment identifies causal effects through the mediator. We study the heterogeneous…

Machine Learning · Statistics 2026-05-12 Yonghan Jung

We study heterogeneity in the effect of a mindset intervention on student-level performance through an observational dataset from the National Study of Learning Mindsets (NSLM). Our analysis uses machine learning (ML) to address the…

Applications · Statistics 2018-11-16 Fredrik D. Johansson

The Linear Threshold Model is a widely used model that describes how information diffuses through a social network. According to this model, an individual adopts an idea or product after the proportion of their neighbors who have adopted it…

Social and Information Networks · Computer Science 2022-01-28 Christopher Tran , Elena Zheleva

Individuals do not respond uniformly to treatments, events, or interventions. Sociologists routinely partition samples into subgroups to explore how the effects of treatments vary by covariates like race, gender, and socioeconomic status.…

Other Statistics · Statistics 2019-09-23 Jennie E. Brand , Jiahui Xu , Bernard Koch , Pablo Geraldo

Mediation analysis seeks to identify and quantify the paths by which an exposure affects an outcome. Intermediate variables which are effected by the exposure and which effect the outcome are known as mediators. There exists extensive work…

Methodology · Statistics 2020-11-13 James P. Long , Ehsan Irajizad , James D. Doecke , Kim-Anh Do , Min Jin Ha

Understanding treatment effect heterogeneity has become an increasingly popular task in various fields, as it helps design personalized advertisements in e-commerce or targeted treatment in biomedical studies. However, most of the existing…

Methodology · Statistics 2024-07-12 Waverly Wei , Xinwei Ma , Jingshen Wang

In human learning, an effective learning methodology is small-group learning: a small group of students work together towards the same learning objective, where they express their understanding of a topic to their peers, compare their…

Machine Learning · Computer Science 2021-03-12 Xuefeng Du , Pengtao Xie

Machine learning approaches have been effective in predicting adverse outcomes in different clinical settings. These models are often developed and evaluated on datasets with heterogeneous patient populations. However, good predictive…

Machine Learning · Computer Science 2018-06-11 Harini Suresh , Jen J. Gong , John Guttag

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare

In the new era of personalization, learning the heterogeneous treatment effect (HTE) becomes an inevitable trend with numerous applications. Yet, most existing HTE estimation methods focus on independently and identically distributed…

Machine Learning · Statistics 2023-01-31 Ye Shen , Runzhe Wan , Hengrui Cai , Rui Song

Causal mediation analysis usually requires strong assumptions, such as ignorability of the mediator, which may not hold in many social and scientific studies. Motivated by a multilevel randomized treatment experiment using functional…

Applications · Statistics 2017-07-11 Yi Zhao , Xi Luo