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Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

The Transformer architecture has shown a remarkable ability in modeling global relationships. However, it poses a significant computational challenge when processing high-dimensional medical images. This hinders its development and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Zhaohu Xing , Tian Ye , Yijun Yang , Guang Liu , Lei Zhu

Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs.…

Histopathological whole slide image (WSI) analysis with deep learning has become a research focus in computational pathology. The current paradigm is mainly based on multiple instance learning (MIL), in which approaches with Transformer as…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hongbo Chu , Qiehe Sun , Jiawen Li , Yuxuan Chen , Lizhong Zhang , Tian Guan , Anjia Han , Yonghong He

Deep learning has revolutionized medical imaging by providing innovative solutions to complex healthcare challenges. Traditional models often struggle to dynamically adjust feature importance, resulting in suboptimal representation,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-29 Kazi Shahriar Sanjid , Md. Tanzim Hossain , Md. Shakib Shahariar Junayed , M. Monir Uddin

Although hyperspectral image (HSI) classification is critical for supporting various environmental applications, it is a challenging task due to the spectral-mixture effect, the spatial-spectral heterogeneity and the difficulty to preserve…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yimin Zhu , Lincoln Linlin Xu

Presenting whole slide images (WSIs) as graph will enable a more efficient and accurate learning framework for cancer diagnosis. Due to the fact that a single WSI consists of billions of pixels and there is a lack of vast annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Milan Aryal , Nasim Yahyasoltani

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

We present PlainMamba: a simple non-hierarchical state space model (SSM) designed for general visual recognition. The recent Mamba model has shown how SSMs can be highly competitive with other architectures on sequential data and initial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Chenhongyi Yang , Zehui Chen , Miguel Espinosa , Linus Ericsson , Zhenyu Wang , Jiaming Liu , Elliot J. Crowley

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Accurate organ and lesion segmentation is a critical prerequisite for computer-aided diagnosis. Convolutional Neural Networks (CNNs), constrained by their local receptive fields, often struggle to capture complex global anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Haodong Chen , Xianfei Han , Qwen

Deep unfolding methods have made impressive progress in restoring 3D hyperspectral images (HSIs) from 2D measurements through convolution neural networks or Transformers in spectral compressive imaging. However, they cannot efficiently…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Jiahua Dong , Hui Yin , Hongliu Li , Wenbo Li , Yulun Zhang , Salman Khan , Fahad Shahbaz Khan

Recent advances in multimodal learning have significantly improved cancer survival risk prediction. However, the joint prognostic potential of protein markers and histopathology images remains underexplored, largely due to the high cost and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Jing Dai , Chen Wu , Ming Wu , Qibin Zhang , Zexi Wu , Jingdong Zhang , Hongming Xu

Hyperspectral object tracking holds great promise due to the rich spectral information and fine-grained material distinctions in hyperspectral images, which are beneficial in challenging scenarios. While existing hyperspectral trackers have…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Long Gao , Yunhe Zhang , Yan Jiang , Weiying Xie , Yunsong Li

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Yuci Liang , Xinheng Lyu , Wenting Chen , Meidan Ding , Jipeng Zhang , Xiangjian He , Song Wu , Xiaohan Xing , Sen Yang , Xiyue Wang , Linlin Shen

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

In this paper, we propose a novel interpretation method tailored to histological Whole Slide Image (WSI) processing. A Deep Neural Network (DNN), inspired by Bag-of-Features models is equipped with a Multiple Instance Learning (MIL) branch…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Magdalini Paschali , Muhammad Ferjad Naeem , Walter Simson , Katja Steiger , Martin Mollenhauer , Nassir Navab

Magnetic resonance imaging (MRI) is critical for neurodevelopmental research, however access to high-field (HF) systems in low- and middle-income countries is severely hindered by their cost. Ultra-low-field (ULF) systems mitigate such…

Hyperspectral Image Classification (HSC) presents significant challenges owing to the high dimensionality and intricate nature of Hyperspectral (HS) data. While traditional Machine Learning (TML) approaches have demonstrated effectiveness,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Muhammad Ahmad , Salvatore Distifano , Adil Mehmood Khan , Manuel Mazzara , Chenyu Li , Hao Li , Jagannath Aryal , Yao Ding , Gemine Vivone , Danfeng Hong