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The use of large language models (LLMs) in healthcare is gaining popularity, but their practicality and safety in clinical settings have not been thoroughly assessed. In high-stakes environments like medical settings, trust and safety are…

Artificial Intelligence · Computer Science 2023-06-29 Salmonn Talebi , Elizabeth Tong , Mohammad R. K. Mofrad

Multi-modal large language models (MLLMs) have been given free rein to explore exciting medical applications with a primary focus on radiology report generation. Nevertheless, the preliminary success in 2D radiology captioning is…

We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

Computation and Language · Computer Science 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

In recent years, large language models (LLMs) have achieved remarkable success in natural language processing (NLP). LLMs require an extreme amount of parameters to attain high performance. As models grow into the trillion-parameter range,…

Computation and Language · Computer Science 2024-09-10 Zhyar Rzgar K Rostam , Sándor Szénási , Gábor Kertész

Reinforcement learning (RL) has demonstrated potential in enhancing the reasoning capabilities of large language models (LLMs), but such training typically demands substantial efforts in creating and annotating data. In this work, we…

Computation and Language · Computer Science 2025-10-06 Hangfan Zhang , Siyuan Xu , Zhimeng Guo , Huaisheng Zhu , Shicheng Liu , Xinrun Wang , Qiaosheng Zhang , Yang Chen , Peng Ye , Lei Bai , Shuyue Hu

Practical guidance on training Large Language Models (LLMs) to leverage Code Interpreter across diverse tasks remains lacking. We present R1-Code-Interpreter, an extension of a text-only LLM trained via multi-turn supervised fine-tuning…

Artificial Intelligence · Computer Science 2026-03-05 Yongchao Chen , Yueying Liu , Junwei Zhou , Yilun Hao , Jingquan Wang , Yang Zhang , Na Li , Chuchu Fan

Large language models (LLMs) have exhibited impressive reasoning abilities on a wide range of complex tasks. However, enhancing these capabilities through post-training remains resource intensive, particularly in terms of data and…

Artificial Intelligence · Computer Science 2025-08-13 Shuo Cai , Su Lu , Qi Zhou , Kejing Yang , Zhijie Sang , Congkai Xie , Hongxia Yang

Existing Large Reasoning Models (LRMs) have shown the potential of reinforcement learning (RL) to enhance the complex reasoning capabilities of Large Language Models~(LLMs). While they achieve remarkable performance on challenging tasks…

Artificial Intelligence · Computer Science 2025-03-19 Huatong Song , Jinhao Jiang , Yingqian Min , Jie Chen , Zhipeng Chen , Wayne Xin Zhao , Lei Fang , Ji-Rong Wen

Large Reasoning Models (LRMs) have emerged as a powerful advancement in multi-step reasoning tasks, offering enhanced transparency and logical consistency through explicit chains of thought (CoT). However, these models introduce novel…

Cryptography and Security · Computer Science 2026-04-15 Jiawei Chen , Yang Yang , Chao Yu , Yu Tian , Zhi Cao , Xue Yang , Linghao Li , Hang Su , Zhaoxia Yin

Multimodal Large Language Models (MLLMs) have demonstrated remarkable capabilities in document understanding. However, their reasoning processes remain largely black-box, making it difficult to ensure reliability and trustworthiness,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Wenwen Yu , Zhibo Yang , Yuliang Liu , Xiang Bai

Scaling inference compute enhances reasoning in large language models (LLMs), with long chains-of-thought (CoTs) enabling strategies like backtracking and error correction. Reinforcement learning (RL) has emerged as a crucial method for…

Computation and Language · Computer Science 2025-02-06 Edward Yeo , Yuxuan Tong , Morry Niu , Graham Neubig , Xiang Yue

Reinforcement learning (RL) with rule-based reward functions has recently shown great promise in enhancing the reasoning depth and generalization ability of vision-language models (VLMs), while maintaining computational efficiency. In spite…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Yizhou Liu , Dingkang Yang , Zizhi Chen , Minghao Han , Xukun Zhang , Keliang Liu , Jingwei Wei , Lihua Zhang

Medical Large Vision-Language Models (Med-LVLMs) have shown strong potential in multimodal diagnostic tasks. However, existing single-agent models struggle to generalize across diverse medical specialties, limiting their performance. Recent…

Machine Learning · Computer Science 2026-01-27 Peng Xia , Jinglu Wang , Yibo Peng , Kaide Zeng , Zihan Dong , Xian Wu , Xiangru Tang , Hongtu Zhu , Yun Li , Linjun Zhang , Shujie Liu , Yan Lu , Huaxiu Yao

Recent regulatory initiatives like the European AI Act and relevant voices in the Machine Learning (ML) community stress the need to describe datasets along several key dimensions for trustworthy AI, such as the provenance processes and…

Digital Libraries · Computer Science 2024-05-27 Joan Giner-Miguelez , Abel Gómez , Jordi Cabot

Accurate and interpretable multi-disease diagnosis remains a critical challenge in medical research, particularly when leveraging heterogeneous multimodal medical data. Current approaches often rely on single-modal data, limiting their…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Yuting Zhang , Kaishen Yuan , Hao Lu , Yutao Yue , Jintai Chen , Kaishun Wu

Fine-tuning Large Language Models (LLMs) typically relies on large quantities of high-quality annotated data, or questions with well-defined ground truth answers in the case of Reinforcement Learning with Verifiable Rewards (RLVR). While…

Artificial Intelligence · Computer Science 2026-04-21 Justin Bauer , Thomas Walshe , Derek Pham , Harit Vishwakarma , Armin Parchami , Frederic Sala , Paroma Varma

Reinforcement learning (RL) for large language models is an energy-intensive endeavor: training can be unstable, and the policy may gradually drift away from its pretrained weights. We present \emph{RLEP}\, -- \,Reinforcement Learning with…

Computation and Language · Computer Science 2025-07-11 Hongzhi Zhang , Jia Fu , Jingyuan Zhang , Kai Fu , Qi Wang , Fuzheng Zhang , Guorui Zhou

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen
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