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Digital pathology plays a vital role across modern medicine, offering critical insights for disease diagnosis, prognosis, and treatment. However, histopathology images often contain artifacts introduced during slide preparation and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zhenzhen Wang , Zhongliang Zhou , Zhuoyu Wen , Jeong Hwan Kook , John B Wojcik , John Kang

The rapid advancements in machine learning have made its application to anomalous diffusion analysis both essential and inevitable. This review systematically introduces the integration of machine learning techniques for enhanced analysis…

Machine Learning · Computer Science 2025-04-01 Wenjie Cai , Yi Hu , Xiang Qu , Hui Zhao , Gongyi Wang , Jing Li , Zihan Huang

Chest X-Ray (CXR) is a widely used clinical imaging modality and has a pivotal role in the diagnosis and prognosis of various lung and heart related conditions. Conventional automated clinical diagnostic tool design strategies relying on…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Abhijeet Parida , Daniel Capellan-Martin , Sara Atito , Muhammad Awais , Maria J. Ledesma-Carbayo , Marius G. Linguraru , Syed Muhammad Anwar

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

The study of the dynamics of natural and artificial systems has provided several examples of deviations from Brownian behavior, generally defined as anomalous diffusion. The investigation of these dynamics can provide a better understanding…

Data Analysis, Statistics and Probability · Physics 2025-08-29 Carlo Manzo

Despite significant progress in generative modelling, existing diffusion models often struggle to produce anatomically precise female pelvic images, limiting their application in gynaecological imaging, where data scarcity and patient…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Johanna P. Müller , Anika Knupfer , Pedro Blöss , Edoardo Berardi Vittur , Bernhard Kainz , Jana Hutter

Ultrasound imaging, despite its widespread use in medicine, often suffers from various sources of noise and artifacts that impact the signal-to-noise ratio and overall image quality. Enhancing ultrasound images requires a delicate balance…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Yuxin Zhang , Clément Huneau , Jérôme Idier , Diana Mateus

Recent advancements in diffusion models have demonstrated significant success in unsupervised anomaly segmentation. For anomaly segmentation, these models are first trained on normal data; then, an anomalous image is noised to an…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Mehrdad Moradi , Kamran Paynabar

Anomaly detection is the problem of recognizing abnormal inputs based on the seen examples of normal data. Despite recent advances of deep learning in recognizing image anomalies, these methods still prove incapable of handling complex…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Nina Shvetsova , Bart Bakker , Irina Fedulova , Heinrich Schulz , Dmitry V. Dylov

The rapid progress of diffusion models highlights the growing need for detecting generated images. Previous research demonstrates that incorporating diffusion-based measurements, such as reconstruction error, can enhance the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Yingsong Huang , Hui Guo , Jing Huang , Bing Bai , Qi Xiong

Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jason Qiu

Diffusion magnetic resonance imaging (dMRI) is a crucial technique in neuroimaging studies, allowing for the non-invasive probing of the underlying structures of brain tissues. Clinical dMRI data is susceptible to various artifacts during…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Sheng Chen , Zihao Tang , Xinyi Wang , Chenyu Wang , Weidong Cai

Current anomaly detection methods primarily focus on low-resolution scenarios. For high-resolution images, conventional downsampling often results in missed detections of subtle anomalous regions due to the loss of fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Ximiao Zhang , Min Xu , Xiuzhuang Zhou

Automatic segmentation of brain abnormalities is challenging, as they vary considerably from one pathology to another. Current methods are supervised and require numerous annotated images for each pathology, a strenuous task. To tackle…

Image and Video Processing · Electrical Eng. & Systems 2021-01-27 Benjamin Lambert , Maxime Louis , Senan Doyle , Florence Forbes , Michel Dojat , Alan Tucholka

Unsupervised anomaly segmentation aims to detect patterns that are distinct from any patterns processed during training, commonly called abnormal or out-of-distribution patterns, without providing any associated manual segmentations. Since…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Ziyun Liang , Harry Anthony , Felix Wagner , Konstantinos Kamnitsas

Detecting visual anomalies in diverse, multi-class real-world images is a significant challenge. We introduce \ours, a novel unsupervised multi-class visual anomaly detection framework. It integrates a Latent Diffusion Model (LDM) with a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Samet Hicsonmez , Abd El Rahman Shabayek , Djamila Aouada

We consider the problem of abnormality localization for clinical applications. While deep learning has driven much recent progress in medical imaging, many clinical challenges are not fully addressed, limiting its broader usage. While…

Computer Vision and Pattern Recognition · Computer Science 2021-12-24 Xi Ouyang , Srikrishna Karanam , Ziyan Wu , Terrence Chen , Jiayu Huo , Xiang Sean Zhou , Qian Wang , Jie-Zhi Cheng

Long-term trajectory anomaly detection is a challenging problem due to the diversity and complex spatiotemporal dependencies in trajectory data. Existing trajectory anomaly detection methods fail to simultaneously consider both the…

Artificial Intelligence · Computer Science 2025-09-23 Chen Wang , Sarah Erfani , Tansu Alpcan , Christopher Leckie

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…

Unsupervised anomaly detection plays a pivotal role in industrial defect inspection and medical image analysis, with most methods relying on the reconstruction framework. However, these methods may suffer from over-generalization, enabling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wei Luo , Peng Xing , Yunkang Cao , Haiming Yao , Weiming Shen , Zechao Li