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Large Language Models (LLMs) have significantly advanced medical question-answering by leveraging extensive clinical data and medical literature. However, the rapid evolution of medical knowledge and the labor-intensive process of manually…

Computation and Language · Computer Science 2025-07-01 Mohammad Reza Rezaei , Reza Saadati Fard , Jayson L. Parker , Rahul G. Krishnan , Milad Lankarany

Much of biomedical and healthcare data is encoded in discrete, symbolic form such as text and medical codes. There is a wealth of expert-curated biomedical domain knowledge stored in knowledge bases and ontologies, but the lack of reliable…

Artificial Intelligence · Computer Science 2020-06-25 David Chang , Ivana Balazevic , Carl Allen , Daniel Chawla , Cynthia Brandt , Richard Andrew Taylor

Knowledge graph completion (KGC) aims to predict missing facts in knowledge graphs (KGs), which is crucial as modern KGs remain largely incomplete. While training KGC models on multiple aligned KGs can improve performance, previous methods…

Computation and Language · Computer Science 2023-12-19 Wei Tang , Zhiqian Wu , Yixin Cao , Yong Liao , Pengyuan Zhou

Due to its complexity, graph learning-based multi-modal integration and classification is one of the most challenging obstacles for disease prediction. To effectively offset the negative impact between modalities in the process of…

Machine Learning · Computer Science 2025-02-14 Jin Liu , Junbin Mao , Hanhe Lin , Hulin Kuang , Shirui Pan , Xusheng Wu , Shan Xie , Fei Liu , Yi Pan

Multimodal data pervades various domains, including healthcare, social media, and transportation, where multimodal graphs play a pivotal role. Machine learning on multimodal graphs, referred to as multimodal graph learning (MGL), is…

Machine Learning · Computer Science 2024-02-09 Ciyuan Peng , Jiayuan He , Feng Xia

Multimodal reasoning in Large Language Models (LLMs) struggles with incomplete knowledge and hallucination artifacts, challenges that textual Knowledge Graphs (KGs) only partially mitigate due to their modality isolation. While Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Junming Liu , Siyuan Meng , Yanting Gao , Song Mao , Pinlong Cai , Guohang Yan , Yirong Chen , Zilin Bian , Ding Wang , Botian Shi

Unsupervised Multiplex Graph Learning (UMGL) aims to learn node representations on various edge types without manual labeling. However, existing research overlooks a key factor: the reliability of the graph structure. Real-world data often…

Machine Learning · Computer Science 2024-09-27 Zhixiang Shen , Shuo Wang , Zhao Kang

Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or…

Computation and Language · Computer Science 2025-01-23 Yuxing Lu , Sin Yee Goi , Xukai Zhao , Jinzhuo Wang

The reliable evaluation of large language models (LLMs) in medical applications remains an open challenge, particularly in capturing the complexity of multi-turn doctor-patient interactions that unfold in real clinical environments.…

Artificial Intelligence · Computer Science 2025-10-15 Yuechun Yu , Han Ying , Haoan Jin , Wenjian Jiang , Dong Xian , Binghao Wang , Zhou Yang , Mengyue Wu

Knowledge Graphs (KGs) play a pivotal role in advancing various AI applications, with the semantic web community's exploration into multi-modal dimensions unlocking new avenues for innovation. In this survey, we carefully review over 300…

The integration of multimodal Electronic Health Records (EHR) data has significantly improved clinical predictive capabilities. Leveraging clinical notes and multivariate time-series EHR, existing models often lack the medical context…

Artificial Intelligence · Computer Science 2024-02-13 Yinghao Zhu , Changyu Ren , Shiyun Xie , Shukai Liu , Hangyuan Ji , Zixiang Wang , Tao Sun , Long He , Zhoujun Li , Xi Zhu , Chengwei Pan

Multi-modal Knowledge Graph Completion (MMKGC) aims to uncover hidden world knowledge in multimodal knowledge graphs by leveraging both multimodal and structural entity information. However, the inherent imbalance in multimodal knowledge…

Artificial Intelligence · Computer Science 2025-07-29 Lijian Li

Multimodal learning combines multiple data modalities, broadening the types and complexity of data our models can utilize: for example, from plain text to image-caption pairs. Most multimodal learning algorithms focus on modeling simple…

Artificial Intelligence · Computer Science 2023-10-13 Minji Yoon , Jing Yu Koh , Bryan Hooi , Ruslan Salakhutdinov

This comprehensive review aims to provide an overview of the current state of Healthcare Knowledge Graphs (HKGs), including their construction, utilization models, and applications across various healthcare and biomedical research domains.…

Existing foundation models, such as CLIP, aim to learn a unified embedding space for multimodal data, enabling a wide range of downstream web-based applications like search, recommendation, and content classification. However, these models…

Machine Learning · Computer Science 2025-04-28 Yufei He , Yuan Sui , Xiaoxin He , Yue Liu , Yifei Sun , Bryan Hooi

Real-world multimodal knowledge graphs (MMKGs) are dynamic, with new entities, relations, and multimodal knowledge emerging over time. Existing continual knowledge graph reasoning (CKGR) methods focus on structural triples and cannot fully…

Computation and Language · Computer Science 2026-04-06 Linyu Li , Zhi Jin , Yichi Zhang , Dongming Jin , Yuanpeng He , Haoran Duan , Gadeng Luosang , Nyima Tashi

Knowledge graphs (KGs) are an important tool for representing complex relationships between entities in the biomedical domain. Several methods have been proposed for learning embeddings that can be used to predict new links in such graphs.…

Artificial Intelligence · Computer Science 2026-05-12 Daniel Daza , Dimitrios Alivanistos , Payal Mitra , Thom Pijnenburg , Michael Cochez , Paul Groth

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

Multi-modal Knowledge Graphs (MMKGs) have been widely applied across various domains for knowledge representation. However, the existing MMKGs are significantly fewer than required, and their construction faces numerous challenges,…

Artificial Intelligence · Computer Science 2025-04-21 Yajing Xu , Zhiqiang Liu , Jiaoyan Chen , Mingchen Tu , Zhuo Chen , Jeff Z. Pan , Yichi Zhang , Yushan Zhu , Wen Zhang , Huajun Chen

Recent studies show that deep learning models achieve good performance on medical imaging tasks such as diagnosis prediction. Among the models, multimodality has been an emerging trend, integrating different forms of data such as chest…

Machine Learning · Computer Science 2022-02-10 Haodi Zhang , Chenyu Xu , Peirou Liang , Ke Duan , Hao Ren , Weibin Cheng , Kaishun Wu