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Large language model (LLM) development is currently driven by large-scale empirical iteration over data mixtures, reward models, routing strategies, and evaluation pipelines. Here, we argue that many central questions in LLM development and…

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Ontologies play a crucial role in organizing and representing knowledge. However, even current ontologies do not encompass all relevant concepts and relationships. Here, we explore the potential of large language models (LLM) to expand an…

Computation and Language · Computer Science 2023-11-14 Antonio Zaitoun , Tomer Sagi , Szymon Wilk , Mor Peleg

Large Language Models (LLMs) have rapidly evolved from text-based systems to multimodal platforms, significantly impacting various sectors including healthcare. This comprehensive review explores the progression of LLMs to Multimodal Large…

Understanding and inferring causal relationships from texts is a core aspect of human cognition and is essential for advancing large language models (LLMs) towards artificial general intelligence. Existing work evaluating LLM causal…

Artificial Intelligence · Computer Science 2026-04-14 Ryan Saklad , Aman Chadha , Oleg Pavlov , Raha Moraffah

Large language models (LLMs) offer the potential to automate a large number of tasks that previously have not been possible to automate, including some in science. There is considerable interest in whether LLMs can automate the process of…

Econometrics · Economics 2024-12-17 Nick Huntington-Klein , Eleanor J. Murray

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Recent breakthroughs in large language models (LLMs) offer unprecedented natural language understanding and generation capabilities. However, existing surveys on LLMs in biomedicine often focus on specific applications or model…

Despite impressive performance on language modelling and complex reasoning tasks, Large Language Models (LLMs) fall short on the same tasks in uncommon settings or with distribution shifts, exhibiting a lack of generalisation ability. By…

Computation and Language · Computer Science 2024-09-11 Gaël Gendron , Bao Trung Nguyen , Alex Yuxuan Peng , Michael Witbrock , Gillian Dobbie

Some argue scale is all what is needed to achieve AI, covering even causal models. We make it clear that large language models (LLMs) cannot be causal and give reason onto why sometimes we might feel otherwise. To this end, we define and…

Artificial Intelligence · Computer Science 2023-08-28 Matej Zečević , Moritz Willig , Devendra Singh Dhami , Kristian Kersting

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

The use of large language models (LLMs) as feature enhancers to optimize node representations, which are then used as inputs for graph neural networks (GNNs), has shown significant potential in graph representation learning. However, the…

Machine Learning · Computer Science 2025-06-12 Hang Gao , Wenxuan Huang , Fengge Wu , Junsuo Zhao , Changwen Zheng , Huaping Liu

This study explores integrating large language models (LLMs) with situational awareness-based planning (SAP) to enhance the decision-making capabilities of AI agents in dynamic and uncertain environments. We employ a multi-agent reasoning…

Artificial Intelligence · Computer Science 2024-06-18 Liman Wang , Hanyang Zhong

Causal structure discovery methods are commonly applied to structured data where the causal variables are known and where statistical testing can be used to assess the causal relationships. By contrast, recovering a causal structure from…

Computation and Language · Computer Science 2024-10-10 Gaël Gendron , Jože M. Rožanec , Michael Witbrock , Gillian Dobbie

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

This position paper examines the use of Large Language Models (LLMs) in social simulation, analyzing their potential and limitations from a computational social science perspective. We first review recent findings on LLMs' ability to…

Artificial Intelligence · Computer Science 2026-03-02 Patrick Taillandier , Jean Daniel Zucker , Arnaud Grignard , Benoit Gaudou , Nghi Quang Huynh , Alexis Drogoul

Large Language Models (LLMs) have emerged as integral tools for reasoning, planning, and decision-making, drawing upon their extensive world knowledge and proficiency in language-related tasks. LLMs thus hold tremendous potential for…

Artificial Intelligence · Computer Science 2024-05-24 Xudong Guo , Kaixuan Huang , Jiale Liu , Wenhui Fan , Natalia Vélez , Qingyun Wu , Huazheng Wang , Thomas L. Griffiths , Mengdi Wang

Large Language Models (LLMs) have emerged as transformative tools in artificial intelligence (AI), exhibiting remarkable capabilities across diverse tasks such as text generation, reasoning, and decision-making. While their success has…

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li