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Related papers: Exposure measurement error correction in longitudi…

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The analysis of environmental mixtures is of growing importance in environmental epidemiology, and one of the key goals in such analyses is to identify exposures and their interactions that are associated with adverse health outcomes.…

Methodology · Statistics 2021-03-22 Srijata Samanta , Joseph Antonelli

The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…

Methodology · Statistics 2020-12-01 Roy Adams , Suchi Saria , Michael Rosenblum

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the…

Methodology · Statistics 2026-05-05 Zhuochao Huang , Kejin Dong , Tuo Lin , Joseph Antonelli

Observational studies are frequently used to estimate the effect of an exposure or treatment on an outcome. To obtain an unbiased estimate of the treatment effect, it is crucial to measure the exposure accurately. A common type of exposure…

Methodology · Statistics 2024-07-02 Suhwan Bong , Kwonsang Lee , Francesca Dominici

Across domains such as medicine, employment, and criminal justice, predictive models often target labels that imperfectly reflect the outcomes of interest to experts and policymakers. For example, clinical risk assessments deployed to…

Machine Learning · Computer Science 2023-05-19 Luke Guerdan , Amanda Coston , Kenneth Holstein , Zhiwei Steven Wu

In randomised trials, continuous endpoints are often measured with some degree of error. This study explores the impact of ignoring measurement error, and proposes methods to improve statistical inference in the presence of measurement…

Methodology · Statistics 2019-08-30 Linda Nab , Rolf H. H. Groenwold , Paco M. J. Welsing , Maarten van Smeden

Observational cohort studies with oversampled exposed subjects are typically implemented to understand the causal effect of a rare exposure. Because the distribution of exposed subjects in the sample differs from the source population,…

Methodology · Statistics 2019-02-14 Sherri Rose

The analysis of data arising from environmental health studies which collect a large number of measures of exposure can benefit from using latent variable models to summarize exposure information. However, difficulties with estimation of…

Applications · Statistics 2009-08-21 Brisa N. Sánchez , Esben Budtz-Jørgensen , Louise M. Ryan

The health effects of environmental exposures have been studied for decades, typically using standard regression models to assess exposure-outcome associations found in observational non-experimental data. We propose and illustrate a…

Applications · Statistics 2017-09-20 Marie-Abele C. Bind , Donald B. Rubin

Many causal models of interest in epidemiology involve longitudinal exposures, confounders and mediators. However, repeated measurements are not always available or used in practice, leading analysts to overlook the time-varying nature of…

Methodology · Statistics 2023-02-21 Lola Etievant , Vivian Viallon

Studies have shown that exposure to air pollution, even at low levels, significantly increases mortality. As regulatory actions are becoming prohibitively expensive, robust evidence to guide the development of targeted interventions to…

Applications · Statistics 2018-02-20 Kwonsang Lee , Dylan S. Small , Francesca Dominici

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

Methodology · Statistics 2025-12-10 Mengqi Lin , Colin Fogarty

We develop new matching estimators for estimating causal quantile exposure-response functions and quantile exposure effects with continuous treatments. We provide identification results for the parameters of interest and establish the…

Methodology · Statistics 2023-08-04 Luca Merlo , Francesca Dominici , Lea Petrella , Nicola Salvati , Xiao Wu

We propose a new approach for estimating causal effects when the exposure is measured with error and confounding adjustment is performed via a generalized propensity score (GPS). Using validation data, we propose a regression calibration…

This study develops a Bayesian hierarchical model to explore the effects of air pollution on respiratory and cardiovascular mortality in Los Angeles County. The model takes into account various pollutants such as PM2.5, PM10, CO, SO2, NO2…

Applications · Statistics 2025-01-29 Yanfei Qu , David A. Stephens

Environmental exposures are often defined using buffer zones around geocoded home addresses, but these static boundaries can miss dynamic daily activity patterns, leading to biased results. This paper presents a novel measurement error…

Methodology · Statistics 2024-10-15 Lin Ge , Ce Yang , David Zucker , Jiaxuan Li , Donna Spiegelman , Molin Wang

Simple sensitivity analysis results are given for differential measurement error of either the exposure or the outcome. In the case of differential measurement error of the outcome it is shown that the true effect of the exposure on the…

Methodology · Statistics 2019-07-02 Tyler J. VanderWeele , Yige Li

The association between multidimensional exposure patterns and outcomes is commonly investigated by first applying cluster analysis algorithms to derive patterns and then estimating the associations. However, errors in the underlying…

Methodology · Statistics 2023-05-31 Timm Intemann , Iris Pigeot

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

Exposure to fine particulate matter ($PM_{2.5}$) poses significant health risks and accurately determining the shape of the relationship between $PM_{2.5}$ and health outcomes has crucial policy ramifications. While various statistical…

Applications · Statistics 2023-06-06 Michael Cork , Daniel Mork , Francesca Dominici