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Global neural dynamics emerge from multi-scale brain structures, with neurons communicating through synapses to form transiently communicating networks. Network activity arises from intercellular communication that depends on the structure…

Neurons and Cognition · Quantitative Biology 2023-11-23 Michiel van der Vlag , Lionel Kusch , Alain Destexhe , Viktor Jirsa , Sandra Diaz-Pier , Jennifer S. Goldman

Arbor is a software library designed for efficient simulation of large-scale networks of biological neurons with detailed morphological structures. It combines customizable neuronal and synaptic mechanisms with high-performance computing,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-16 Jannik Luboeinski , Sebastian Schmitt , Shirin Shafiee , Thorsten Hater , Fabian Bösch , Christian Tetzlaff

We introduce Arbor, a performance portable library for simulation of large networks of multi-compartment neurons on HPC systems. Arbor is open source software, developed under the auspices of the HBP. The performance portability is by…

Neurons and Cognition · Quantitative Biology 2019-04-12 Nora Abi Akar , Ben Cumming , Vasileios Karakasis , Anne Küsters , Wouter Klijn , Alexander Peyser , Stuart Yates

The simulation of whole-brain dynamics should reproduce realistic spontaneous and evoked neural activity across different scales, including emergent rhythms, spatio-temporal activation patterns, and macroscale complexity. Once a…

Current AMR simulations require algorithms that are highly parallelized and manage memory efficiently. As compute engines grow larger, AMR simulations will require algorithms that achieve new levels of efficient parallelization and memory…

Instrumentation and Methods for Astrophysics · Physics 2011-10-10 Jonathan Carroll-Nellenback , Brandon Shroyer , Adam Frank , Chen Ding

This paper introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the…

Neurons and Cognition · Quantitative Biology 2024-06-26 Ignacio Martín , Gorka Zamora , Jan Fousek , Michael Schirner , Petra Ritter , Viktor Jirsa , Gustavo Deco , Gustavo Patow

We introduce SABR-CLIMB, a novel video model simulating human movement in rock climbing environments using a virtual avatar. Our diffusion transformer predicts the sample instead of noise in each diffusion step and ingests entire videos to…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Sai Mandava

The field of artificial intelligence has significantly advanced over the past decades, inspired by discoveries from the fields of biology and neuroscience. The idea of this work is inspired by the process of self-organization of cortical…

Neural and Evolutionary Computing · Computer Science 2022-01-10 Artem R. Muliukov , Laurent Rodriguez , Benoit Miramond , Lyes Khacef , Joachim Schmidt , Quentin Berthet , Andres Upegui

Neural dynamics underlie behaviors from memory to sleep, yet identifying mechanisms for higher-order phenomena (e.g., social interaction) is experimentally challenging. Existing whole-brain models often fail to scale to single-neuron…

Neurons and Cognition · Quantitative Biology 2025-11-03 Sam Fatehmanesh Vegas , Matt Thomson , James Gornet , David Prober

Neurophysiological decoding, fundamental to advancing brain-computer interface (BCI) technologies, has significantly benefited from recent advances in deep learning. However, existing decoding approaches largely remain constrained to…

Signal Processing · Electrical Eng. & Systems 2025-08-07 Di Wu , Yifei Jia , Siyuan Li , Shiqi Zhao , Jie Yang , Mohamad Sawan

Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jiaxing Xu , Jingying Ma , Xin Lin , Yuxiao Liu , Kai He , Qika Lin , Yiping Ke , Yang Li , Dinggang Shen , Mengling Feng

Current Adaptive Mesh Refinement (AMR) simulations require algorithms that are highly parallelized and manage memory efficiently. As compute engines grow larger, AMR simulations will require algorithms that achieve new levels of efficient…

Solar and Stellar Astrophysics · Physics 2015-03-19 Jonathan J. Carroll-Nellenback , Brandon Shroyer , Adam Frank , Chen Ding

A complete understanding of the brain requires an integrated description of the numerous scales of neural organization. It means studying the interplay of genes, synapses, and even whole brain regions which ultimately leads to different…

Neurons and Cognition · Quantitative Biology 2022-08-09 Charley Presigny , Fabrizio De Vico Fallani

Large language models struggle to maintain strict adherence to structured workflows in high-stakes domains such as healthcare triage. Monolithic approaches that encode entire decision structures within a single prompt are prone to…

Artificial Intelligence · Computer Science 2026-03-03 Luís Silva , Diogo Gonçalves , Catarina Farinha , Clara Matos , Luís Ungaro

Connecting brain and behavior is a longstanding issue in the areas of behavioral science, artificial intelligence, and neurobiology. As is standard among models of artificial and biological neural networks, an analogue of the fully mature…

Neurons and Cognition · Quantitative Biology 2022-05-12 Stefan Dvoretskii , Ziyi Gong , Ankit Gupta , Jesse Parent , Bradly Alicea

As deep learning systems are scaled up to many billions of parameters, relating their internal structure to external behaviors becomes very challenging. Although daunting, this problem is not new: Neuroscientists and cognitive scientists…

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Binary spike coding enables sparse and event-driven computation in spiking neural networks (SNNs), yet its 1-bit-per-timestep representation fundamentally limits information throughput. This bottleneck becomes increasingly restrictive in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Dewei Bai , Hongxiang Peng , Jiajun Mei , Yang Ren , Hong Qu , Dawen Xia , Zhang Yi

Visual neural decoding seeks to reconstruct or infer perceived visual stimuli from brain activity patterns, providing critical insights into human cognition and enabling transformative applications in brain-computer interfaces and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Wenjiang Zhang , Sifeng Wang , Yuwei Su , Xinyu Li , Chen Zhang , Suyu Zhong
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