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The promise of quantum computing to address complex problems requiring high computational resources has long been hindered by the intrinsic and demanding requirements of quantum hardware development. Nonetheless, the current state of…

Quantum Physics · Physics 2024-07-10 Daniel F Perez-Ramirez

Solving hard optimization problems is one of the most promising application domains for quantum computers due to the ubiquity of such problems in industry and the availability of broadly applicable quantum speedups. However, the ability of…

Quantum Physics · Physics 2025-07-25 Zichang He , Rudy Raymond , Ruslan Shaydulin , Marco Pistoia

Quantum computing is an emerging field on the multidisciplinary interface between physics, engineering, and computer science with the potential to make a large impact on computational intelligence (CI). The aim of this paper is to introduce…

Variational quantum algorithms have emerged as a cornerstone of contemporary quantum algorithms research. While they have demonstrated considerable promise in solving problems of practical interest, efficiently determining the minimal…

Quantum Physics · Physics 2026-02-04 Daniil Rabinovich , Andrey Kardashin , Soumik Adhikary

Motivated by near term quantum computing hardware limitations, combinatorial optimization problems that can be addressed by current quantum algorithms and noisy hardware with little or no overhead are used to probe capabilities of quantum…

Optimization and Control · Mathematics 2026-05-15 Elijah Pelofske , Andreas Bärtschi , Stephan Eidenbenz

Solving combinatorial optimization problems on near-term quantum devices has gained a lot of attraction in recent years. Currently, most works have focused on single-objective problems, whereas many real-world applications need to consider…

Quantum Physics · Physics 2025-06-06 Linus Ekstrom , Hao Wang , Sebastian Schmitt

Obtaining exact solutions to combinatorial optimization problems using classical computing is computationally expensive. The current tenet in the field is that quantum computers can address these problems more efficiently. While promising…

Quantum Physics · Physics 2025-12-23 Xiaoyang Wang , Yahui Chai , Xu Feng , Yibin Guo , Karl Jansen , Cenk Tüysüz

We develop a hardware-efficient ansatz for variational optimization, derived from existing ansatze in the literature, that parametrizes subsets of all interactions in the Cost Hamiltonian in each layer. We treat gate orderings as a…

Quantum alternating operator ansatz (QAOA) has a strong connection to the adiabatic algorithm, which it can approximate with sufficient depth. However, it is unclear to what extent the lessons from the adiabatic regime apply to QAOA as…

Noisy intermediate-scale quantum computers (NISQ computers) are now readily available, motivating many researchers to experiment with Variational Quantum Algorithms (VQAs). Among them, the Quantum Approximate Optimization Algorithm (QAOA)…

Optimization and Control · Mathematics 2024-08-13 Camille Grange , Michael Poss , Eric Bourreau

Variational quantum algorithms and, in particular, variants of the varational quantum eigensolver have been proposed to address combinatorial optimization (CO) problems. Using only shallow ansatz circuits, these approaches are deemed…

Quantum Physics · Physics 2026-04-14 Tim Schwägerl , Yahui Chai , Tobias Hartung , Karl Jansen , Stefan Kühn

We develop circuit implementations for digital-level quantum Hamiltonian dynamics simulation algorithms suitable for implementation on a reconfigurable quantum computer, such as trapped ions. Our focus is on the co-design of a problem, its…

Quantum Physics · Physics 2020-04-09 Yunseong Nam , Dmitri Maslov

While variational quantum algorithms (VQAs) have demonstrated considerable success in unconstrained optimization, their application to constrained combinatorial problems face a trade-off. Penalty-based methods, despite their circuit…

Quantum Physics · Physics 2026-03-09 Hui-Min Li , Yuan-Liang Han , Zhi-Xi Wang , Shao-Ming Fei

The Quantum Approximate Optimization Algorithm (QAOA), which is a variational quantum algorithm, aims to give sub-optimal solutions of combinatorial optimization problems. It is widely believed that QAOA has the potential to demonstrate…

Analytical and practical evidence indicates the advantage of quantum computing solutions over classical alternatives. Quantum-based heuristics relying on the variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2023-01-05 Sarthak Gupta , Vassilis Kekatos

Variational quantum algorithms, which consist of optimal parameterized quantum circuits, are promising for demonstrating quantum advantages in the noisy intermediate-scale quantum (NISQ) era. Apart from classical computational resources,…

Quantum Physics · Physics 2024-12-30 Chen Qian , Wei-Feng Zhuang , Rui-Cheng Guo , Meng-Jun Hu , Dong E. Liu

Quantum computers are expected to accelerate solving combinatorial optimization problems, including algorithms such as Grover adaptive search and quantum approximate optimization algorithm (QAOA). However, many combinatorial optimization…

Quantum Physics · Physics 2023-05-05 Takuya Yoshioka , Keita Sasada , Yuichiro Nakano , Keisuke Fujii

Quantum optimization algorithms hold the promise of solving classically hard, discrete optimization problems in practice. The requirement of encoding such problems in a Hamiltonian realized with a finite -- and currently small -- number of…

Quantum Physics · Physics 2023-07-10 Yifeng Rocky Zhu , David Joseph , Cong Ling , Florian Mintert

The Quantum Approximate Optimization Algorithm (QAOA) is a hybrid quantum-classical variational algorithm designed to tackle combinatorial optimization problems. Despite its promise for near-term quantum applications, not much is currently…

Quantum Physics · Physics 2020-06-26 Leo Zhou , Sheng-Tao Wang , Soonwon Choi , Hannes Pichler , Mikhail D. Lukin

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels