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Volumetric Modulated Arc Therapy (VMAT) is a cornerstone of modern radiation therapy, enabling highly conformal tumor irradiation and healthy-tissue sparing. Yet, its planning solves inverse and nested optimization for multi-leaf…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Isabella Poles , Simon Arberet , Riqiang Gao , Martin Kraus , Marco D. Santambrogio , Florin C. Ghesu , Ali Kamen , Dorin Comaniciu

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

$\textbf{Purpose:}$ To assess the viability of a physics-based, deterministic and adjoint-capable algorithm for performing treatment planning system independent dose calculations and for computing dosimetric differences caused by anatomical…

Medical Physics · Physics 2024-04-02 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

The fitting of physical models is often done only using a single target observable. However, when multiple targets are considered, the fitting procedure becomes cumbersome, there being no easy way to quantify the robustness of the model for…

Chemical Physics · Physics 2022-01-12 Rodrigo A. Vargas-Hernández , Chern Chuang , Paul Brumer

With the rising imaging resolution of handheld devices, existing multi-exposure image fusion algorithms struggle to generate a high dynamic range image with ultra-high resolution in real-time. Apart from that, there is a trend to design a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Xin Su , Zhuoran Zheng

Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2021-05-06 Mohamed S. Elmahdy , Laurens Beljaards , Sahar Yousefi , Hessam Sokooti , Fons Verbeek , U. A. van der Heide , Marius Staring

Fundus photography and Optical Coherence Tomography Angiography (OCT-A) are two commonly used modalities in ophthalmic imaging. With the development of deep learning algorithms, fundus image processing, especially retinal vessel…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Weilin Fu , Lennart Husvogt , Stefan Ploner James G. Fujimoto Andreas Maier

Optical metasurfaces are planar arrangements of subwavelength meta-atoms that implement a wide range of transformations on incident light. The design of efficient metasurfaces requires that the responses of and interactions among meta-atoms…

Optics · Physics 2021-01-19 Mahdad Mansouree , Andrew McClung , Sarath Samudrala , Amir Arbabi

Objective: Machine learning (ML) based radiation treatment (RT) planning addresses the iterative and time-consuming nature of conventional inverse planning. Given the rising importance of Magnetic resonance (MR) only treatment planning…

Medical Physics · Physics 2022-06-13 Aly Khalifa , Jeff Winter , Inmaculada Navarro , Chris McIntosh , Thomas G. Purdie

We perform detailed calculations of electroweak radiative corrections to parity violating lepton scattering with a proton target up to quadratic and reducible two-loop level using a covariant approach. Our numerical results are presented at…

High Energy Physics - Phenomenology · Physics 2025-07-31 Mahumm Ghaffar , Aleksandrs Aleksejevs , Svetlana Barkanova

Geometric uncertainty can degrade treatment quality in radiation therapy. While margins and robust optimization mitigate these effects, they provide only implicit control over clinical goal fulfillment probability. We therefore develop a…

Medical Physics · Physics 2026-01-14 Albin Fredriksson , Erik Engwall , Jenneke de Jong , Johan Sundström

Purpose:The recently proposed IPO-IMPT framework allows simultaneous optimization of dose, dose rate, and LET for FLASH treatment planning. Finding solutions to IPO-IMPT is difficult due to computational intensiveness. Nevertheless, an…

This article presents an extended author's version based on our previous work, where we introduced the Multiple Overlapping Tiles (MOT) method for palm vein image enhancement. To better reflect the specific operations involved, we rename…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Kaveen Perera , Fouad Khelifi , Ammar Belatreche

This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model to three different internal treatment planning…

We present POWHEG predictions for photon-jet correlations at RHIC and the LHC. We show that the total transverse-momentum spectrum of photons and jets is modified not only by medium, but also by higher-order QCD effects, as is the…

High Energy Physics - Phenomenology · Physics 2017-09-25 M. Klasen

Optical focusing through/inside scattering media, like multimode fiber and biological tissues, has significant impact in biomedicine yet considered challenging due to strong scattering nature of light. Previously, promising progress has…

This study investigates the convergence properties of a collection of iterative electron ptychography methods, under low electron doses ($<$ 10$^3$ $e^-/A^2$) and gives particular attention to the impact of the user-defined update…

Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu

Delineation of tumors and organs-at-risk permits detecting and correcting changes in the patients' anatomy throughout the treatment, making it a core step of adaptive proton therapy (APT). Although AI-based auto-contouring technologies have…