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Resting-state functional magnetic resonance imaging (rs-fMRI) offers a non-invasive approach to examining abnormal brain connectivity associated with brain disorders. Graph neural network (GNN) gains popularity in fMRI representation…

Quantitative Methods · Quantitative Biology 2023-08-22 Junhao Zhang , Qianqian Wang , Xiaochuan Wang , Lishan Qiao , Mingxia Liu

Elucidating the intricate relationship between brain structure and function, both in healthy and pathological conditions, is a key challenge for modern neuroscience. Recent technical and methodological progress in neuroimaging has helped…

Neurons and Cognition · Quantitative Biology 2015-05-01 Ibai Diez , Paolo Bonifazi , Iñaki Escudero , Beatriz Mateos , Miguel A. Muñoz , Sebastiano Stramaglia , Jesus M. Cortes

The relationship of network structure and dynamics is one of most extensively investigated problems in the theory of complex systems of the last years. Understanding this relationship is of relevance to a range of disciplines -- from…

Modularity plays an important role in brain networks' architecture and influences its dynamics and the ability to integrate and segregate different modules of cerebral regions. Alterations in community structure are associated with several…

Neurons and Cognition · Quantitative Biology 2018-05-14 M. Cinelli , I. Echegoyen , M. Oliveira , S. Orellana , T. Gili

Schizophrenia (SZ) is a prevalent mental disorder characterized by cognitive, emotional, and behavioral changes. Symptoms of SZ include hallucinations, illusions, delusions, lack of motivation, and difficulties in concentration. Diagnosing…

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This…

Schizophrenia (SZ) is a severe brain disorder marked by diverse cognitive impairments, abnormalities in brain structure, function, and genetic factors. Its complex symptoms and overlap with other psychiatric conditions challenge traditional…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Nagur Shareef Shaik , Teja Krishna Cherukuri , Vince D. Calhoun , Dong Hye Ye

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

The human brain has a complex, intricate functional architecture. While many studies primarily emphasize pairwise interactions, delving into high-order associations is crucial for a comprehensive understanding of how functional brain…

Neurons and Cognition · Quantitative Biology 2023-10-30 Qiang Li , Vince D. Calhoun , Adithya Ram Ballem , Shujian Yu , Jesus Malo , Armin Iraji

Cognitive task classification using machine learning plays a central role in decoding brain states from neuroimaging data. By integrating machine learning with brain network analysis, complex connectivity patterns can be extracted from…

Machine Learning · Computer Science 2026-01-01 Debasis Maji , Arghya Banerjee , Debaditya Barman

This paper presents a novel multimodal framework to distinguish between different symptom classes of subjects in the schizophrenia spectrum and healthy controls using audio, video, and text modalities. We implemented Convolution Neural…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Gowtham Premananth , Yashish M. Siriwardena , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

The white-matter (micro-)structural architecture of the brain promotes synchrony among neuronal populations, giving rise to richly patterned functional connections. A fundamental problem for systems neuroscience is determining the best way…

Neurons and Cognition · Quantitative Biology 2022-11-15 Yueting Li , Qingyue Wei , Ehsan Adeli , Kilian M. Pohl , Qingyu Zhao

Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…

Neurons and Cognition · Quantitative Biology 2024-01-31 Fuad Noman , Chee-Ming Ting , Hakmook Kang , Raphael C. -W. Phan , Brian D. Boyd , Warren D. Taylor , Hernando Ombao

Resting-state fMRI (rs-fMRI) functional connectivity (FC) analysis provides valuable insights into the relationships between different brain regions and their potential implications for neurological or psychiatric disorders. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Xiatian Zhang , Sisi Zheng , Hubert P. H. Shum , Haozheng Zhang , Nan Song , Mingkang Song , Hongxiao Jia

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

Neurons and Cognition · Quantitative Biology 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

Machine Learning · Computer Science 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

Coherence is a widely used measure to assess linear relationships between time series. However, it fails to capture nonlinear dependencies. To overcome this limitation, this paper introduces the notion of residual spectral density as a…

Statistics Theory · Mathematics 2024-05-21 Yuichi Goto , Xuze Zhang , Benjamin Kedem , Shuo Chen