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Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised schemes that condition on measured data. While these approaches…

Medical Physics · Physics 2026-03-18 George Webber , Alexander Hammers , Andrew P King , Andrew J Reader

Many material and biological samples in scientific imaging are characterized by non-local repeating structures. These are studied using scanning electron microscopy and electron tomography. Sparse sampling of individual pixels in a 2D image…

Computer Vision and Pattern Recognition · Computer Science 2017-11-09 Suhas Sreehari , S. V. Venkatakrishnan , Brendt Wohlberg , Lawrence F. Drummy , Jeffrey P. Simmons , Charles A. Bouman

Ptychography is a coherent diffraction imaging method that uses phase retrieval techniques to reconstruct complex-valued images. It achieves this by sequentially illuminating overlapping regions of a sample with a coherent beam and…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Alexander Denker , Johannes Hertrich , Zeljko Kereta , Silvia Cipiccia , Ecem Erin , Simon Arridge

Since the various MR contrasts of a given anatomy contain redundant information, one contrast can be used to guide the reconstruction of another undersampled contrast acquired subsequently in the same session. To solve this reconstruction…

Plug-and-Play Priors (PnP) is a popular framework for solving imaging inverse problems by integrating learned priors in the form of denoisers trained to remove Gaussian noise from images. In standard PnP methods, the denoiser is applied…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Edward P. Chandler , Shirin Shoushtari , Brendt Wohlberg , Ulugbek S. Kamilov

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman

This study aims to improve photon counting CT (PCCT) image resolution using denoising diffusion probabilistic models (DDPM). Although DDPMs have shown superior performance when applied to various computer vision tasks, their effectiveness…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Chuang Niu , Christopher Wiedeman , Mengzhou Li , Jonathan S Maltz , Ge Wang

Score-based diffusion models have shown significant promise in the field of sparse-view CT reconstruction. However, the projection dataset is large and riddled with redundancy. Consequently, applying the diffusion model to unprocessed data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-16 Pengfei Yu , Bin Huang , Minghui Zhang , Weiwen Wu , Shaoyu Wang , Qiegen Liu

Plug-and-play priors (PnP) is a broadly applicable methodology for solving inverse problems by exploiting statistical priors specified as denoisers. Recent work has reported the state-of-the-art performance of PnP algorithms using…

Machine Learning · Computer Science 2021-01-25 Yu Sun , Zihui Wu , Xiaojian Xu , Brendt Wohlberg , Ulugbek S. Kamilov

Plug-and-play (PnP) prior is a well-known class of methods for solving imaging inverse problems by computing fixed-points of operators combining physical measurement models and learned image denoisers. While PnP methods have been…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Weijie Gan , Shirin Shoushtari , Yuyang Hu , Jiaming Liu , Hongyu An , Ulugbek S. Kamilov

Plug-and-Play Priors (PnP) is a well-known class of methods for solving inverse problems in computational imaging. PnP methods combine physical forward models with learned prior models specified as image denoisers. A common issue with the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Edward P. Chandler , Shirin Shoushtari , Jiaming Liu , M. Salman Asif , Ulugbek S. Kamilov

Electromagnetic (EM) imaging is an important tool for non-invasive sensing with low-cost and portable devices. One emerging application is EM stroke imaging, which enables early diagnosis and continuous monitoring of brain strokes.…

Signal Processing · Electrical Eng. & Systems 2025-09-08 Rui Guo , Yi Zhang , Yhonatan Kvich , Tianyao Huang , Maokun Li , Yonina C. Eldar

Diffusion models have demonstrated exceptional ability in modeling complex image distributions, making them versatile plug-and-play priors for solving imaging inverse problems. However, their reliance on large-scale clean datasets for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-16 Weimin Bai , Weiheng Tang , Enze Ye , Siyi Chen , Wenzheng Chen , He Sun

The Plug-and-Play (PnP) ADMM algorithm is a powerful image restoration framework that allows advanced image denoising priors to be integrated into physical forward models to generate high quality image restoration results. However, despite…

Image and Video Processing · Electrical Eng. & Systems 2019-05-21 Stanley H. Chan

Diffusion-based sparse-view CT (SVCT) imaging has achieved remarkable advancements in recent years, thanks to its more stable generative capability. However, recovering reliable image content and visually consistent textures is still a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Tianqi Wang , Wenchao Du , Hongyu Yang

Score-based diffusion models achieve state-of-the-art performance for inverse problems, but their practical deployment is hindered by long inference times and cumbersome hyperparameter tuning. While pretrained diffusion models can be reused…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Julio Oscanoa , Irmak Sivgin , Cagan Alkan , Daniel Ennis , John Pauly , Mert Pilanci , Shreyas Vasanawala

Colorectal cancer (CRC) is a significant global health concern, and early detection through screening plays a critical role in reducing mortality. While deep learning models have shown promise in improving polyp detection, classification,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Jia Yu , Yan Zhu , Peiyao Fu , Tianyi Chen , Junbo Huang , Quanlin Li , Pinghong Zhou , Zhihua Wang , Fei Wu , Shuo Wang , Xian Yang

Model-based methods play a key role in the reconstruction of compressed sensing (CS) MRI. Finding an effective prior to describe the statistical distribution of the image family of interest is crucial for model-based methods. Plug-and-play…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Tao Hong , Xiaojian Xu , Jason Hu , Jeffrey A. Fessler

Diffusion models (DMs) have recently shown outstanding capabilities in modeling complex image distributions, making them expressive image priors for solving Bayesian inverse problems. However, most existing DM-based methods rely on…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Zihui Wu , Yu Sun , Yifan Chen , Bingliang Zhang , Yisong Yue , Katherine L. Bouman

Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong