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As data shift or new data become available, updating clinical machine learning models may be necessary to maintain or improve performance over time. However, updating a model can introduce compatibility issues when the behavior of the…

Machine Learning · Statistics 2023-08-11 Erkin Ötleş , Brian T. Denton , Jenna Wiens

Adversarial training often suffers from a robustness-accuracy trade-off, where achieving high robustness comes at the cost of accuracy. One approach to mitigate this trade-off is leveraging invariance regularization, which encourages model…

Machine Learning · Computer Science 2025-08-29 Futa Waseda , Ching-Chun Chang , Isao Echizen

We study the problem of multiple hypothesis testing for multidimensional data when inter-correlations are present. The problem of multiple comparisons is common in many applications. When the data is multivariate and correlated, existing…

Statistics Theory · Mathematics 2015-06-02 Mahdis Azadbakhsh , Xin Gao , Hanna Jankowski

Integrating the outputs of multiple classifiers via combiners or meta-learners has led to substantial improvements in several difficult pattern recognition problems. In the typical setting investigated till now, each classifier is trained…

Machine Learning · Computer Science 2007-05-23 Kagan Tumer , Joydeep Ghosh

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Volumetry is one of the principal downstream applications of 3D medical image segmentation, for example, to detect abnormal tissue growth or for surgery planning. Conformal Prediction is a promising framework for uncertainty quantification,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-30 Benjamin Lambert , Florence Forbes , Senan Doyle , Michel Dojat

Combining multi-site data can strengthen and uncover trends, but is a task that is marred by the influence of site-specific covariates that can bias the data and therefore any downstream analyses. Post-hoc multi-site correction methods…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Pedro Borges , Richard Shaw , Thomas Varsavsky , Kerstin Klaser , David Thomas , Ivana Drobnjak , Sebastien Ourselin , M Jorge Cardoso

We study variants of the average treatment effect on the treated with population parameters replaced by their sample counterparts. For each estimand, we derive the limiting distribution with respect to a semiparametric efficient estimator…

Methodology · Statistics 2024-02-12 Andrew Yiu

Image harmonization, which involves adjusting the foreground of a composite image to attain a unified visual consistency with the background, can be conceptualized as an image-to-image translation task. Diffusion models have recently…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Pengfei Zhou , Fangxiang Feng , Xiaojie Wang

Determining the number of common factors is an important and practical topic in high dimensional factor models. The existing literatures are mainly based on the eigenvalues of the covariance matrix. Due to the incomparability of the…

Methodology · Statistics 2019-09-25 Jianqing Fan , Jianhua Guo , Shurong Zheng

It has been proposed that complex populations, such as those that arise in genomics studies, may exhibit dependencies among observations as well as among variables. This gives rise to the challenging problem of analyzing unreplicated…

Machine Learning · Statistics 2018-06-08 Michael Hornstein , Roger Fan , Kerby Shedden , Shuheng Zhou

Adapting to dynamic data distributions is a practical yet challenging task. One effective strategy is to use a model ensemble, which leverages the diverse expertise of different models to transfer knowledge to evolving data distributions.…

Forecast combination and model averaging have become popular tools in forecasting and prediction, both of which combine a set of candidate estimates with certain weights and are often shown to outperform single estimates. A data-driven…

Statistics Theory · Mathematics 2025-10-31 Jiahui Zou , Andrey Vasnev , Wendun Wang , Xinyu Zhang

The growing demand for personalized decision-making has led to a surge of interest in estimating the Conditional Average Treatment Effect (CATE). Various types of CATE estimators have been developed with advancements in machine learning and…

Machine Learning · Computer Science 2024-11-04 Yiyan Huang , Cheuk Hang Leung , Siyi Wang , Yijun Li , Qi Wu

The amount of data collected from patients involved in clinical trials is continuously growing. All patient characteristics are potential covariates that could be used to improve clinical trial analysis and power. However, the restricted…

Methodology · Statistics 2021-03-29 Samuel Branders , Alvaro Pereira , Guillaume Bernard , Marie Ernst , Adelin Albert

Conformal prediction has emerged as a popular technique for facilitating valid predictive inference across a spectrum of machine learning models, under minimal assumption of exchangeability. Recently, Hoff (2023) showed that full conformal…

Statistics Theory · Mathematics 2025-11-24 Pankaj Bhagwat , Linglong Kong , Bei Jiang

Epidemiological compartmental models are useful for understanding infectious disease propagation and directing public health policy decisions. Calibration of these models is an important step in offering accurate forecasts of disease…

Machine Learning · Computer Science 2023-12-12 Nikunj Gupta , Anh Mai , Azza Abouzied , Dennis Shasha

A fundamental problem in statistics is to compare the outcomes attained by members of subpopulations. This problem arises in the analysis of randomized controlled trials, in the analysis of A/B tests, and in the assessment of fairness and…

Methodology · Statistics 2021-12-02 Mark Tygert

Machine learning models are updated as new data is acquired or new architectures are developed. These updates usually increase model performance, but may introduce backward compatibility errors, where individual users or groups of users see…

Machine Learning · Computer Science 2021-12-21 Martin Bertran , Natalia Martinez , Alex Oesterling , Guillermo Sapiro

Cumulant mapping has been recently suggested [Frasinski, Phys. Chem. Chem. Phys. 24, 207767 (2022)] as an efficient approach to observing multi-particle fragmentation pathways, while bypassing the restrictions of the usual…

Chemical Physics · Physics 2025-04-11 S. Patchkovskii , J. Mikosch