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Related papers: R2MED: A Benchmark for Reasoning-Driven Medical Re…

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Existing multimodal retrieval benchmarks largely emphasize semantic matching on daily-life images and offer limited diagnostics of professional knowledge and complex reasoning. To address this gap, we introduce ARK, a benchmark designed to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Yijie Lin , Guofeng Ding , Haochen Zhou , Haobin Li , Mouxing Yang , Xi Peng

Medical Anomaly Detection (MedAD) presents a significant opportunity to enhance diagnostic accuracy using Large Multimodal Models (LMMs) to interpret and answer questions based on medical images. However, the reliance on Supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haitao Zhang , Yingying Wang , Jiaxiang Wang , Haote Xu , Hongyang Zhang , Yirong Chen , Yue Huang , Xinghao Ding

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

Computation and Language · Computer Science 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

In recent years, accurately and quickly deploying medical large language models (LLMs) has become a trend. Among these, retrieval-augmented generation (RAG) has garnered attention due to rapid deployment and privacy protection. However, the…

Computation and Language · Computer Science 2025-08-06 Penglei Sun , Yixiang Chen , Xiang Li , Xiaowen Chu

Accurate multi-modal document retrieval is crucial for Retrieval-Augmented Generation (RAG), yet existing benchmarks do not fully capture real-world challenges with their current design. We introduce REAL-MM-RAG, an automatically generated…

Information Retrieval · Computer Science 2025-02-19 Navve Wasserman , Roi Pony , Oshri Naparstek , Adi Raz Goldfarb , Eli Schwartz , Udi Barzelay , Leonid Karlinsky

Predicting future clinical outcomes from electronic health records (EHR) remains challenging due to the complexity and heterogeneity of patient data. LLMs have shown strong potential for such predictive tasks, yet existing approaches mainly…

Computation and Language · Computer Science 2026-05-05 Yushi Cao , Yiming Chen , Hongchao Jiang , Hung-yi Lee , Robby T. Tan

Despite strong performance on existing benchmarks, it remains unclear whether large language models can reason over genuinely novel scientific information. Most evaluations score end-to-end RAG pipelines, where reasoning is confounded with…

Clinical decision-making in radiology increasingly benefits from artificial intelligence (AI), particularly through large language models (LLMs). However, traditional retrieval-augmented generation (RAG) systems for radiology question…

Retrieving visual and textual information from medical literature and hospital records can enhance diagnostic accuracy for clinical image interpretation. However, multimodal retrieval-augmented diagnosis is highly challenging. We explore a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nir Mazor , Tom Hope

Multimodal large language models (MLLMs) hold significant potential in medical applications, including disease diagnosis and clinical decision-making. However, these tasks require highly accurate, context-sensitive, and professionally…

Computation and Language · Computer Science 2025-09-01 Meidan Ding , Jipeng Zhang , Wenxuan Wang , Cheng-Yi Li , Wei-Chieh Fang , Hsin-Yu Wu , Haiqin Zhong , Wenting Chen , Linlin Shen

Existing benchmarks for evaluating the clinical reasoning capabilities of large language models (LLMs) often lack a clear definition of "clinical reasoning" as a construct, fail to capture the full breadth of interdependent tasks within a…

Electronic Health Record (EHR) retrieval plays a pivotal role in various clinical tasks, but its development has been severely impeded by the lack of publicly available benchmarks. In this paper, we introduce a novel public EHR retrieval…

Information Retrieval · Computer Science 2025-04-09 Zhengyun Zhao , Hongyi Yuan , Jingjing Liu , Haichao Chen , Huaiyuan Ying , Songchi Zhou , Yue Zhong , Sheng Yu

Reasoning stands as a cornerstone of intelligence, enabling the synthesis of existing knowledge to solve complex problems. Despite remarkable progress, existing reasoning benchmarks often fail to rigorously evaluate the nuanced reasoning…

Existing medical reasoning benchmarks for vision-language models primarily focus on analyzing a patient's condition based on an image from a single visit. However, this setting deviates significantly from real-world clinical practice, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Junyi Zhang , Jia-Chen Gu , Wenbo Hu , Yu Zhou , Robinson Piramuthu , Nanyun Peng

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

Artificial Intelligence · Computer Science 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

While Retrieval-Augmented Generation (RAG) has been swiftly adopted in scientific and clinical QA systems, a comprehensive evaluation benchmark in the medical domain is lacking. To address this gap, we introduce the Medical…

Computation and Language · Computer Science 2026-02-12 Liz Li , Wei Zhu

Medical reasoning models remain constrained by parametric knowledge and are thus susceptible to forgetting and hallucinations. DeepResearch (DR) models ground outputs in verifiable evidence from tools and perform strongly in general…

Artificial Intelligence · Computer Science 2026-02-05 Zihan Wang , Hao Wang , Shi Feng , Xiaocui Yang , Daling Wang , Yiqun Zhang , Jinghao Lin , Haihua Yang , Xiaozhong Ji

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

Retrieval-Augmented Generation (RAG) offers a well-established path to grounding large language model (LLM) outputs in external knowledge, yet the question of which retrieval strategy works best in a high-stakes domain such as biomedicine…

Computation and Language · Computer Science 2026-05-05 Devi Prasad Bal , Subhashree Puhan