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Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

While hallucinations of large language models could been alleviated through retrieval-augmented generation and citation generation, how the model utilizes internal knowledge is still opaque, and the trustworthiness of its generated answers…

Computation and Language · Computer Science 2025-04-22 Jiajun Shen , Tong Zhou , Yubo Chen , Delai Qiu , Shengping Liu , Kang Liu , Jun Zhao

Large Language Models (LLMs) encounter challenges with the unique syntax of specific domains, such as biomolecules. Existing fine-tuning or modality alignment techniques struggle to bridge the domain knowledge gap and understand complex…

Biomolecules · Quantitative Biology 2024-06-28 Jinzhe Liu , Xiangsheng Huang , Zhuo Chen , Yin Fang

Recent advancements in Large Language Models (LLMs) have significantly improved their performance across various Natural Language Processing (NLP) tasks. However, LLMs still struggle with generating non-factual responses due to limitations…

Computation and Language · Computer Science 2024-09-10 Taeho Hwang , Soyeong Jeong , Sukmin Cho , SeungYoon Han , Jong C. Park

Retrieval-augmented generation (RAG) enhances large language models (LLMs) by incorporating additional information from retrieval. However, studies have shown that LLMs still face challenges in effectively using the retrieved information,…

Computation and Language · Computer Science 2024-06-13 Shicheng Xu , Liang Pang , Mo Yu , Fandong Meng , Huawei Shen , Xueqi Cheng , Jie Zhou

Radiology report generation (RRG) models typically focus on individual exams, often overlooking the integration of historical visual or textual data, which is crucial for patient follow-ups. Traditional methods usually struggle with long…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Tengfei Liu , Jiapu Wang , Yongli Hu , Mingjie Li , Junfei Yi , Xiaojun Chang , Junbin Gao , Baocai Yin

Retrieval-Augmented Generation (RAG) significantly improves the performance of Large Language Models (LLMs) on knowledge-intensive tasks. However, varying response quality across LLMs under RAG necessitates intelligent routing mechanisms,…

Computation and Language · Computer Science 2025-10-20 Jiarui Zhang , Xiangyu Liu , Yong Hu , Chaoyue Niu , Fan Wu , Guihai Chen

Large Language Models (LLMs) are increasingly adopted across domains such as education, healthcare, and finance. In healthcare, LLMs support tasks including disease diagnosis, abnormality classification, and clinical decision-making. Among…

Cryptography and Security · Computer Science 2026-03-31 Payel Bhattacharjee , Fengwei Tian , Geoffrey D. Rubin , Joseph Y. Lo , Nirav Merchant , Heidi Hanson , John Gounley , Ravi Tandon

Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…

Computation and Language · Computer Science 2025-09-30 Qinggang Zhang , Shengyuan Chen , Yuanchen Bei , Zheng Yuan , Huachi Zhou , Zijin Hong , Hao Chen , Yilin Xiao , Chuang Zhou , Junnan Dong , Yi Chang , Xiao Huang

Retrieval-augmented generation (RAG) enhances the question-answering (QA) abilities of large language models (LLMs) by integrating external knowledge. However, adapting general-purpose RAG systems to specialized fields such as science and…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hui Liu , Sreyashi Nag , Zhenwei Dai , Yaochen Xie , Xianfeng Tang , Chen Luo , Yang Li , Joyce C. Ho , Carl Yang , Qi He

In this chapter, we consider generative information retrieval evaluation from two distinct but interrelated perspectives. First, large language models (LLMs) themselves are rapidly becoming tools for evaluation, with current research…

Information Retrieval · Computer Science 2025-01-31 Marwah Alaofi , Negar Arabzadeh , Charles L. A. Clarke , Mark Sanderson

Large language models (LLMs) are increasingly recognized as valuable tools across the medical environment, supporting clinical, research, and administrative workflows. However, strict privacy and network security regulations in hospital…

Computation and Language · Computer Science 2026-01-09 Seokhwan Ko , Donghyeon Lee , Jaewoo Chun , Hyungsoo Han , Junghwan Cho

Large Language Models (LLMs) have been integrated into recommendation systems to enhance user behavior comprehension. The Retrieval Augmented Generation (RAG) technique is further incorporated into these systems to retrieve more relevant…

Information Retrieval · Computer Science 2025-02-12 Jian Xu , Sichun Luo , Xiangyu Chen , Haoming Huang , Hanxu Hou , Linqi Song

Large language models (LLMs) have significantly advanced the field of natural language generation. However, they frequently generate unverified outputs, which compromises their reliability in critical applications. In this study, we propose…

Computation and Language · Computer Science 2025-02-18 Alexandru Lecu , Adrian Groza , Lezan Hawizy

The emergence of Large Language Models (LLMs) has significantly advanced natural language processing, but these models often generate factually incorrect information, known as "hallucination". Initial retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2024-11-12 Yujia Zhou , Zheng Liu , Zhicheng Dou

Retrieval-Augmented Generation (RAG) has significantly mitigated the hallucinations of Large Language Models (LLMs) by grounding the generation with external knowledge. Recent extensions of RAG to graph-based retrieval offer a promising…

Machine Learning · Computer Science 2025-09-23 Jialin Chen , Houyu Zhang , Seongjun Yun , Alejandro Mottini , Rex Ying , Xiang Song , Vassilis N. Ioannidis , Zheng Li , Qingjun Cui

Large Language Models (LLMs) suffer from hallucinations and outdated knowledge due to their reliance on static training data. Retrieval-Augmented Generation (RAG) mitigates these issues by integrating external dynamic information for…

In recent years, multimodal large language models (MLLMs) have made significant strides by training on vast high-quality image-text datasets, enabling them to generally understand images well. However, the inherent difficulty in explicitly…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuanze Lin , Yunsheng Li , Dongdong Chen , Weijian Xu , Ronald Clark , Philip Torr , Lu Yuan

Neural image-to-text radiology report generation systems offer the potential to improve radiology reporting by reducing the repetitive process of report drafting and identifying possible medical errors. However, existing report generation…

Computation and Language · Computer Science 2021-04-14 Yasuhide Miura , Yuhao Zhang , Emily Bao Tsai , Curtis P. Langlotz , Dan Jurafsky