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Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…
Large Language Models (LLMs) have demonstrated impressive capabilities in natural language processing tasks, such as text generation and semantic understanding. However, their performance on numerical reasoning tasks, such as basic…
Building a deep research agent today is an exercise in glue code: the same backbone evaluated on the same benchmark can report different accuracies in different papers because harness and tool registry all differ, and integrating a new…
Large language models (LLMs) offer significant potential in enhancing psychiatric practice, from improving diagnostic accuracy to streamlining clinical documentation and therapeutic support. However, existing evaluation resources heavily…
Current Vision-Language Models (VLMs) struggle to ground anatomical regions in 3D medical images and reason about them in a step-by-step manner, a key requirement of real-world diagnostic assessment. This ability is essential for aligning…
Medical reasoning in large language models (LLMs) aims to emulate clinicians' diagnostic thinking, but current benchmarks such as MedQA-USMLE, MedMCQA, and PubMedQA often mix reasoning with factual recall. We address this by separating 11…
Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…
The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…
The rapid evolution of Large Language Models (LLMs) presents a promising solution to the global shortage of mental health professionals. However, their alignment with essential counseling competencies remains underexplored. We introduce…
The emergence of deep research systems presents significant capabilities in problem-solving, extending from basic queries to sophisticated research tasks. However, existing benchmarks primarily evaluate these systems as agents for web…
Large Language Models are commonly judged by their scores on standard benchmarks, yet such scores often overstate real capability since they mask the mix of skills a task actually demands. For example, ARC is assumed to test reasoning,…
Despite the remarkable advancements and widespread applications of deep neural networks, their ability to perform reasoning tasks remains limited, particularly in domains requiring structured, abstract thought. In this paper, we investigate…
Large language model (LLM) agents are increasingly capable of automating components of machine learning development, yet existing biomedical benchmarks mainly focus on question answering, reasoning, and tool usage, or evaluate only narrow…
We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…
This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, including computer science, mathematics, natural sciences,…
Large Language Models (LLMs) are increasingly deployed for knowledge synthesis, yet their capacity for compositional generalization in scientific knowledge remains under-characterized. Existing benchmarks primarily focus on single-turn…
Large Language Models have demonstrated strong performance on many established reasoning benchmarks. However, these benchmarks primarily evaluate structured skills like quantitative problem-solving, leaving a gap in assessing flexible,…
Large Language Models (LLMs) are increasingly deployed in critical applications requiring reliable reasoning, yet their internal reasoning processes remain difficult to evaluate systematically. Existing methods focus on final-answer…
Reasoning about Actions and Change (RAC) has historically played a pivotal role in solving foundational AI problems, such as the frame problem. It has driven advancements in AI fields, such as non-monotonic and commonsense reasoning. RAC…
Mental health disorders are one of the most serious diseases in the world. Most people with such a disease lack access to adequate care, which highlights the importance of training models for the diagnosis and treatment of mental health…