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Molecular generation and molecular property prediction are both crucial for drug discovery, but they are often developed independently. Inspired by recent studies, which demonstrate that diffusion model, a prominent generative approach, can…

Machine Learning · Computer Science 2025-04-07 Shikun Feng , Yuyan Ni , Yan Lu , Zhi-Ming Ma , Wei-Ying Ma , Yanyan Lan

Retrieval-Augmented Generation (RAG) has become a popular technique for enhancing the reliability and utility of Large Language Models (LLMs) by grounding responses in external documents. Traditional RAG systems rely on Optical Character…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Alexander Most , Joseph Winjum , Ayan Biswas , Shawn Jones , Nishath Rajiv Ranasinghe , Dan O'Malley , Manish Bhattarai

We report on the second harmonic generation performance of a ferroelectric nematic fluid consisting of the prototype ferroelectric nematic liquid crystal, RM734 mixed with the classical chromophore Dispersed-Orange 3 at 5 %wt. The mixture…

Soft Condensed Matter · Physics 2025-02-25 J. Ortega , C. L. Folcia , T. Sierra

We demonstrate a data mining approach to discover and develop new organic nonlinear optical crystals that produce intense pulses of terahertz radiation. We mine the Cambridge Structural Database for non-centrosymmetric materials and use…

3D Gaussian Splatting (3DGS) has recently advanced radiance field reconstruction by offering superior capabilities for novel view synthesis and real-time rendering speed. However, its strategy of blending optimization and adaptive density…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Rong Liu , Rui Xu , Yue Hu , Meida Chen , Andrew Feng

Two-dimensional lead halide perovskites are promising materials for optoelectronics due to the tunability of their properties with the number of lead halide layers and the choice of an organic spacer. Physical understanding for the rational…

Organic molecular crystals are ideally placed to become next-generation piezoelectric materials due to their diverse chemistries that can be used to engineer tailor-made solid-state assemblies. Using crystal engineering principles, and…

Materials Science · Physics 2024-12-11 Shubham Vishnoi , Geetu Kumari , Robert Guest , Pierre-André Cazade , Sarah Guerin

The design of functional materials with desired properties is essential in driving technological advances in areas like energy storage, catalysis, and carbon capture. Generative models provide a new paradigm for materials design by directly…

Pre-trained Language Models have emerged as promising tools for predicting molecular properties, yet their development is in its early stages, necessitating further research to enhance their efficacy and address challenges such as…

Machine Learning · Computer Science 2023-10-24 Eduardo Soares , Akihiro Kishimoto , Emilio Vital Brazil , Seiji Takeda , Hiroshi Kajino , Renato Cerqueira

Analysis of molecular scale interactions and chemical structure offers an enormous opportunity to tune material properties for targeted applications. However, designing materials from molecular scale is a grand challenge owing to the…

Materials Science · Physics 2021-11-19 Praneeth S Ramesh , Tarak K Patra

The discovery of new materials is essential for enabling technological advancements. Computational approaches for predicting novel materials must effectively learn the manifold of stable crystal structures within an infinite design space.…

We show how generative machine learning can be used for the rapid computation of strongly dynamical electron diffraction directly from crystal structures, specifically in large-angle convergent-beam electron diffraction (LACBED) patterns.…

Materials Science · Physics 2025-07-31 Joseph J. Webb , Richard Beanland , Rudolf A. Römer

We develop and test new machine learning strategies for accelerating molecular crystal structure ranking and crystal property prediction using tools from geometric deep learning on molecular graphs. Leveraging developments in graph-based…

Materials Science · Physics 2024-07-29 Michael Kilgour , Jutta Rogal , Mark Tuckerman

Generative AI has the potential to revolutionize drug discovery. Yet, despite recent advances in deep learning, existing models cannot generate molecules that satisfy all desired physicochemical properties. Herein, we describe IDOLpro, a…

Chemical Physics · Physics 2025-04-29 Amit Kadan , Kevin Ryczko , Erika Lloyd , Adrian Roitberg , Takeshi Yamazaki

Optical techniques are finding widespread use in analytical chemistry for chemical and bio-chemical analysis. During the past decade, there has been an increasing emphasis on miniaturization of chemical analysis systems and naturally this…

Optics · Physics 2007-11-22 Niels Asger Mortensen , Sanshui Xiao , Jesper Pedersen

Photonic hyper-crystals combine the most interesting features of hyperbolic metamaterials and photonic crystals. Since the dispersion law of extraordinary photons in hyperbolic metamaterials does not exhibit the usual diffraction limit,…

Optics · Physics 2019-05-27 Igor I. Smolyaninov

We introduce a framework, which we denote as the augmented estimate sequence, for deriving fast algorithms with provable convergence guarantees. We use this framework to construct a new first-order scheme, the Accelerated Composite Gradient…

Optimization and Control · Mathematics 2019-04-24 Mihai I. Florea , Sergiy A. Vorobyov

Artificial intelligence-based methods are becoming increasingly effective at screening libraries of polymers down to a selection that is manageable for experimental inquiry. The vast majority of presently adopted approaches for polymer…

Materials Science · Physics 2023-02-16 Rishi Gurnani , Christopher Kuenneth , Aubrey Toland , Rampi Ramprasad

Learned progressive image compression is gaining momentum as it allows improved image reconstruction as more bits are decoded at the receiver. We propose a progressive image compression method in which an image is first represented as a…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Alberto Presta , Enzo Tartaglione , Attilio Fiandrotti , Marco Grangetto , Pamela Cosman

Deep learning has proven to yield fast and accurate predictions of quantum-chemical properties to accelerate the discovery of novel molecules and materials. As an exhaustive exploration of the vast chemical space is still infeasible, we…

Machine Learning · Statistics 2020-01-10 Niklas W. A. Gebauer , Michael Gastegger , Kristof T. Schütt
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