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Prediction of protein-ligand (PL) binding affinity remains the key to drug discovery. Popular approaches in recent years involve graph neural networks (GNNs), which are used to learn the topology and geometry of PL complexes. However, GNNs…

Machine Learning · Computer Science 2022-05-17 Dmitrii Gavrilev , Nurlybek Amangeldiuly , Sergei Ivanov , Evgeny Burnaev

Binary quantization represents the most extreme form of compression, reducing weights to +/-1 for maximal memory and computational efficiency. While recent sparsity-aware binarization achieves sub-1-bit compression via weight pruning, it…

Machine Learning · Computer Science 2026-04-10 Hao Gu , Lujun Li , Hao Wang , Lei Wang , Zheyu Wang , Bei Liu , Jiacheng Liu , Qiyuan Zhu , Sirui Han , Yike Guo

We study a new paradigm of knowledge transfer that aims at encoding graph topological information into graph neural networks (GNNs) by distilling knowledge from a teacher GNN model trained on a complete graph to a student GNN model…

Machine Learning · Computer Science 2023-01-18 Chenxiao Yang , Qitian Wu , Junchi Yan

Recently, deep neural networks (DNNs) have been regarded as the state-of-the-art classification methods in a wide range of applications, especially in image classification. Despite the success, the huge number of parameters blocks its…

Machine Learning · Statistics 2017-12-18 Guangxi Li , Jinmian Ye , Haiqin Yang , Di Chen , Shuicheng Yan , Zenglin Xu

Modern pre-trained transformers have rapidly advanced the state-of-the-art in machine learning, but have also grown in parameters and computational complexity, making them increasingly difficult to deploy in resource-constrained…

Machine Learning · Computer Science 2022-10-04 Zechun Liu , Barlas Oguz , Aasish Pappu , Lin Xiao , Scott Yih , Meng Li , Raghuraman Krishnamoorthi , Yashar Mehdad

We propose $\mathcal{T}$ruth $\mathcal{T}$able net ($\mathcal{TT}$net), a novel Convolutional Neural Network (CNN) architecture that addresses, by design, the open challenges of interpretability, formal verification, and logic gate…

Artificial Intelligence · Computer Science 2023-02-03 Adrien Benamira , Tristan Guérand , Thomas Peyrin , Trevor Yap , Bryan Hooi

Embedding tables are usually huge in click-through rate (CTR) prediction models. To train and deploy the CTR models efficiently and economically, it is necessary to compress their embedding tables at the training stage. To this end, we…

Machine Learning · Computer Science 2024-08-07 Shiwei Li , Huifeng Guo , Lu Hou , Wei Zhang , Xing Tang , Ruiming Tang , Rui Zhang , Ruixuan Li

Linear block transform coding remains a fundamental component of image and video compression. Although the Discrete Cosine Transform (DCT) is widely employed in all current compression standards, its sub-optimality has sparked ongoing…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Alessandro Gnutti , Chia-Hao Kao , Wen-Hsiao Peng , Riccardo Leonardi

Graph Contrastive Learning (GCL) has emerged as a powerful paradigm for training Graph Neural Networks (GNNs) in the absence of task-specific labels. However, its scalability on large-scale graphs is hindered by the intensive message…

Machine Learning · Computer Science 2025-11-12 Xiang Chen , Kun Yue , Wenjie Liu , Zhenyu Zhang , Liang Duan

Current video coding standards, including H.264/AVC, HEVC, and VVC, employ discrete cosine transform (DCT), discrete sine transform (DST), and secondary to Karhunen-Loeve transforms (KLTs) decorrelate the intra-prediction residuals.…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Wen-Yang Lu , Eduardo Pavez , Antonio Ortega , Xin Zhao , Shan Liu

Knowledge distillation (KD) techniques have emerged as a powerful tool for transferring expertise from complex teacher models to lightweight student models, particularly beneficial for deploying high-performance models in…

Machine Learning · Computer Science 2025-10-28 Paul Agbaje , Arkajyoti Mitra , Afia Anjum , Pranali Khose , Ebelechukwu Nwafor , Habeeb Olufowobi

In the realm of graph learning, there is a category of methods that conceptualize graphs as hierarchical structures, utilizing node clustering to capture broader structural information. While generally effective, these methods often rely on…

Machine Learning · Computer Science 2024-12-25 Siyuan Huang , Yunchong Song , Jiayue Zhou , Zhouhan Lin

The accurate recovery of constituent-level optical properties from integrating sphere measurements is a central analytical challenge in pharmaceutical analysis, food science, and biomedical diagnostics. Neural network autoencoders can…

Optics · Physics 2026-05-13 Martin Hohmann

The use of deep neural networks in edge computing devices hinges on the balance between accuracy and complexity of computations. Ternary Connect (TC) \cite{lin2015neural} addresses this issue by restricting the parameters to three levels…

Machine Learning · Computer Science 2018-11-14 Samyak Parajuli , Aswin Raghavan , Sek Chai

Graph neural networks (GNNs) are powerful models that have been successful in various graph representation learning tasks. Whereas gradient boosted decision trees (GBDT) often outperform other machine learning methods when faced with…

Machine Learning · Computer Science 2021-04-01 Sergei Ivanov , Liudmila Prokhorenkova

Integrating Pre-trained Language Models (PLMs) with Graph Neural Networks (GNNs) remains a central challenge in text-rich heterophilic graph learning. We propose a novel integration framework that enables effective fusion between powerful…

Computation and Language · Computer Science 2025-10-09 Aarush Sinha

Structured pruning of Generative Pre-trained Transformers (GPTs) offers a promising path to efficiency but often suffers from irreversible performance degradation due to the discarding of transformer blocks. In this paper, we introduce…

Machine Learning · Computer Science 2025-12-16 Zehua Pei , Hui-Ling Zhen , Xianzhi Yu , Sinno Jialin Pan , Mingxuan Yuan , Bei Yu

Transfer learning has become the dominant paradigm for many natural language processing tasks. In addition to models being pretrained on large datasets, they can be further trained on intermediate (supervised) tasks that are similar to the…

Computation and Language · Computer Science 2022-09-13 Benjamin Minixhofer , Milan Gritta , Ignacio Iacobacci

GPT-2 and BERT demonstrate the effectiveness of using pre-trained language models (LMs) on various natural language processing tasks. However, LM fine-tuning often suffers from catastrophic forgetting when applied to resource-rich tasks. In…

Computation and Language · Computer Science 2022-06-22 Jiacheng Yang , Mingxuan Wang , Hao Zhou , Chengqi Zhao , Yong Yu , Weinan Zhang , Lei Li

Creating visual layouts is a critical step in graphic design. Automatic generation of such layouts is essential for scalable and diverse visual designs. To advance conditional layout generation, we introduce BLT, a bidirectional layout…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Xiang Kong , Lu Jiang , Huiwen Chang , Han Zhang , Yuan Hao , Haifeng Gong , Irfan Essa