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Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Topological data analysis is an emerging area in exploratory data analysis and data mining. Its main tool, persistent homology, has become a popular technique to study the structure of complex, high-dimensional data. In this paper, we…

Graphics · Computer Science 2017-10-04 Mustafa Hajij , Bei Wang , Carlos Scheidegger , Paul Rosen

Deformation K-theory associates to each discrete group G a spectrum built from spaces of finite dimensional unitary representations of G. In all known examples, this spectrum is 2-periodic above the rational cohomological dimension of G…

K-Theory and Homology · Mathematics 2018-05-09 Daniel A. Ramras

We study the local scaling properties associated with straight line periodic orbits in homogeneous Hamiltonian systems, whose stability undergoes repeated oscillations as a function of one parameter. We give strong evidence of local scaling…

chao-dyn · Physics 2009-10-28 A. Lakshminarayan , M. S. Santhanam , V. B. Sheorey

This paper introduces a method to detect each geometrically significant loop that is a geodesic circle (an isometric embedding of $S^1$) and a bottleneck loop (meaning that each of its perturbations increases the length) in a geodesic space…

Algebraic Topology · Mathematics 2024-11-13 Žiga Virk

In this work, a complete homotopic interpretation on the periodic table of topological insulators and superconductors has been derived by establishing the loop sequence of the corresponding classifying spaces. In our approach, each…

Mathematical Physics · Physics 2013-11-13 Chunbo Zhao

We study semi-dynamical systems associated to delay differential equations. We give a simple criteria to obtain weak and strong persistence and provide sufficient conditions to guarantee uniform persistence. Moreover, we show the existence…

Classical Analysis and ODEs · Mathematics 2020-02-04 Pablo Amster , Melanie Bondorevsky

We develop in this paper a theoretical framework for the topological study of time series data. Broadly speaking, we describe geometrical and topological properties of sliding window (or time-delay) embeddings, as seen through the lens of…

Algebraic Topology · Mathematics 2013-11-26 Jose Perea , John Harer

We compute the equivariant homology and cohomology of projective spaces with integer coefficients. More precisely, in the case of cyclic groups, we show that the cellular filtration of the projective space $P(k\rho )$, of lines inside…

Algebraic Topology · Mathematics 2025-09-24 Samik Basu , Pinka Dey , Aparajita Karmakar

Homology features of spaces which appear in applications, for instance 3D meshes, are among the most important topological properties of these objects. Given a non-trivial cycle in a homology class, we consider the problem of computing a…

Computational Geometry · Computer Science 2022-03-18 Erin Wolf Chambers , Salman Parsa , Hannah Schreiber

We study bifurcations of area-preserving maps, both orientable (symplectic) and non-orientable, with quadratic homoclinic tangencies. We consider one and two parameter general unfoldings and establish results related to the appearance of…

Dynamical Systems · Mathematics 2015-09-02 Amadeu Delshams , Marina Gonchenko , Sergey Gonchenko

Computational topology provides a tool, persistent homology, to extract quantitative descriptors from structured objects (images, graphs, point clouds, etc). These descriptors can then be involved in optimization problems, typically as a…

Computational Geometry · Computer Science 2026-03-27 Mathieu Carriere , Yuichi Ike , Théo Lacombe , Naoki Nishikawa

Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori information. Classically, different phases and phase…

Quantitative Methods · Quantitative Biology 2021-01-19 Dhananjay Bhaskar , William Y. Zhang , Ian Y. Wong

In this work, we explore links between natural homology and persistent homology for the classification of directed spaces. The former is an algebraic invariant of directed spaces, a semantic model of concurrent programs. The latter was…

Algebraic Topology · Mathematics 2024-08-07 Cameron Calk , Eric Goubault , Philippe Malbos

The classical K\"{u}nneth formula in algebraic topology describes the homology of a product space in terms of that of its factors. In this paper, we prove K\"{u}nneth-type theorems for the persistent homology of the categorical and tensor…

Algebraic Topology · Mathematics 2019-10-15 Hitesh Gakhar , Jose A. Perea

We construct some new cohomology theories for topological groups and Lie groups and study some of its basic properties. For example, we introduce a cohomology theory based on measurable cochains which are continuous in a neighbourhood of…

General Topology · Mathematics 2010-09-24 Arati S. Khedekar , C. S. Rajan

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Persistent (co)homology is a central construction in topological data analysis, where it is used to quantify prominence of features in data to produce stable descriptors suitable for downstream analysis. Persistence is challenging to…

Computational Geometry · Computer Science 2024-10-23 Arnur Nigmetov , Dmitriy Morozov

We discuss and review recent developments in the area of applied algebraic topology, such as persistent homology and barcodes. In particular, we discuss how these are related to understanding more about manifold learning from random point…

Probability · Mathematics 2015-03-13 Robert J. Adler , Omer Bobrowski , Matthew S. Borman , Eliran Subag , Shmuel Weinberger

Persistent homology is a popular computational tool for analyzing the topology of point clouds, such as the presence of loops or voids. However, many real-world datasets with low intrinsic dimensionality reside in an ambient space of much…

Machine Learning · Computer Science 2024-11-01 Sebastian Damrich , Philipp Berens , Dmitry Kobak