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Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Swift and accurate blood smear analysis is an effective diagnostic method for leukemia and other hematological malignancies. However, manual leukocyte count and morphological evaluation using a microscope is time-consuming and prone to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Chandravardhan Singh Raghaw , Arnav Sharma , Shubhi Bansal , Mohammad Zia Ur Rehman , Nagendra Kumar

Spatial transcriptomics enables spatial gene expression profiling, motivating computational models that capture spatially conditioned regulatory relationships. We introduce SAGE-FM, a lightweight spatial transcriptomics foundation model…

Machine Learning · Computer Science 2026-01-23 Xianghao Zhan , Jingyu Xu , Yuanning Zheng , Zinaida Good , Olivier Gevaert

Large-scale foundation models have become the mainstream deep learning method, while in civil engineering, the scale of AI models is strictly limited. In this work, a vision foundation model is introduced for crack segmentation. Two…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Kang Ge , Chen Wang , Yutao Guo , Yansong Tang , Zhenzhong Hu , Hongbing Chen

Foundation models like ChatGPT and Sora that are trained on a huge scale of data have made a revolutionary social impact. However, it is extremely challenging for sensors in many different fields to collect similar scales of natural images…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Chenyang Lei , Liyi Chen , Jun Cen , Xiao Chen , Zhen Lei , Felix Heide , Qifeng Chen , Zhaoxiang Zhang

Single-cell data integration can provide a comprehensive molecular view of cells, and many algorithms have been developed to remove unwanted technical or biological variations and integrate heterogeneous single-cell datasets. Despite their…

Quantitative Methods · Quantitative Biology 2024-03-04 Rong Ma , Eric D. Sun , David Donoho , James Zou

Several modern genomic technologies, such as DNA-Methylation arrays, measure spatially registered probes that number in the hundreds of thousands across multiplechromosomes. The measured probes are by themselves less interesting…

Applications · Statistics 2016-11-16 John Nagorski , Genevera I. Allen

One-shot object detection aims at detecting novel objects according to merely one given instance. With extreme data scarcity, current approaches explore various feature fusions to obtain directly transferable meta-knowledge. Yet, their…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yizhou Zhao , Xun Guo , Yan Lu

Recognized as a potential resource for quantum technologies and a possible testbed for fundamental physics, the control and preparation of nonclassical states of mechanical oscillators has been explored extensively. Within optomechanics,…

Quantum Physics · Physics 2024-07-30 Andrew J. Shepherd , Ryan O. Behunin

Despite the breakthroughs in biomarker discovery facilitated by differential gene analysis, challenges remain, particularly at the single-cell level. Traditional methodologies heavily rely on user-supplied cell annotations, focusing on…

Genomics · Quantitative Biology 2023-12-29 Chenyu Liu , Yong Jin Kweon , Jun Ding

Many modern biological assays, including RNA sequencing, yield integer-valued counts that reflect the number of molecules detected. These measurements are often not at the desired resolution: while the unit of interest is typically a single…

Machine Learning · Computer Science 2026-03-06 Nic Fishman , Gokul Gowri , Tanush Kumar , Jiaqi Lu , Valentin de Bortoli , Jonathan S. Gootenberg , Omar Abudayyeh

The success of large language models has inspired the computer vision community to explore image segmentation foundation model that is able to zero/few-shot generalize through prompt engineering. Segment-Anything(SAM), among others, is the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Haojie Zhang , Yongyi Su , Xun Xu , Kui Jia

Recent advancements in foundation models, typically trained with self-supervised learning on large-scale and diverse datasets, have shown great potential in medical image analysis. However, due to the significant spatial heterogeneity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Lingxiao Luo , Xuanzhong Chen , Bingda Tang , Xinsheng Chen , Rong Han , Chengpeng Hu , Yujiang Li , Ting Chen

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Wearable medical sensors (WMSs) are revolutionizing smart healthcare by enabling continuous, real-time monitoring of user physiological signals, especially in the field of consumer healthcare. The integration of WMSs and modern machine…

Machine Learning · Computer Science 2024-10-22 Chia-Hao Li , Niraj K. Jha

Reliable crack detection and segmentation are vital for structural health monitoring, yet the scarcity of well-annotated data constitutes a major challenge. To address this limitation, we propose a novel context-aware generative framework…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Nassim Sadallah , Mohand Saïd Allili

We present a novel method for automated identification of putative cell types from single-cell RNA-seq (scRNA-seq) data. By iteratively applying a machine learning approach to an initial clustering of gene expression profiles of a given set…

Quantitative Methods · Quantitative Biology 2020-04-22 Zhichao Miao , Pablo Moreno , Ni Huang , Irene Papatheodorou , Alvis Brazma , Sarah A Teichmann

Accurate, noninvasive detection of isocitrate dehydrogenase (IDH) mutation is essential for effective glioma management. Traditional methods rely on invasive tissue sampling, which may fail to capture a tumor's spatial heterogeneity. While…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Somayeh Farahani , Marjaneh Hejazi , Antonio Di Ieva , Sidong Liu

Our research is motivated by the urgent global issue of a large population affected by retinal diseases, which are evenly distributed but underserved by specialized medical expertise, particularly in non-urban areas. Our primary objective…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Deependra Singh , Saksham Agarwal , Subhankar Mishra

Structural heart disease (SHD) is a prevalent condition with many undiagnosed cases, and early detection is often limited by the high cost and accessibility constraints of echocardiography (ECHO). Recent studies show that artificial…

Applications · Statistics 2026-03-04 Ya Zhou , Zhaohong Sun , Tianxiang Hao , Xiangjie Li