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Despite the revolutionary impact of AI and the development of locally trained algorithms, achieving widespread generalized learning from multi-modal data in medical AI remains a significant challenge. This gap hinders the practical…
Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…
Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…
Subretinal injection is a critical procedure for delivering therapeutic agents to treat retinal diseases such as age-related macular degeneration (AMD). However, retinal motion caused by physiological factors such as respiration and…
Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…
Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…
The recent surge of foundation models in computer vision and natural language processing opens up perspectives in utilizing multi-modal clinical data to train large models with strong generalizability. Yet pathological image datasets often…
Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…
Magnetic resonance imaging (MRI), especially functional MRI (fMRI) and diffusion MRI (dMRI), is essential for studying neurodegenerative diseases. However, missing modalities pose a major barrier to their clinical use. Although GAN- and…
Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…
In the field of medical imaging, the advent of deep learning, especially the application of convolutional neural networks (CNNs) has revolutionized the analysis and interpretation of medical images. Nevertheless, deep learning methods…
The development of multi-label deep learning models for retinal disease classification is often hindered by the scarcity of large, expertly annotated clinical datasets due to patient privacy concerns and high costs. The recent release of…
An accurate binding affinity prediction between T-cell receptors and epitopes contributes decisively to develop successful immunotherapy strategies. Some state-of-the-art computational methods implement deep learning techniques by…
Ultra-Wide-Field (UWF) retinal imaging has revolutionized retinal diagnostics by providing a comprehensive view of the retina. However, it often suffers from quality-degrading factors such as blurring and uneven illumination, which obscure…
Early and accurate classification of retinal diseases is critical to counter vision loss and for guiding clinical management of retinal diseases. In this study, we proposed a deep learning method for retinal disease classification utilizing…
Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…
Accurate segmentation of retinal images plays a crucial role in aiding ophthalmologists in diagnosing retinopathy of prematurity (ROP) and assessing its severity. However, due to their underdeveloped, thinner vessels, manual annotation in…
Developing reliable and generalizable deep learning systems for medical imaging faces significant obstacles due to spurious correlations, data imbalances, and limited text annotations in datasets. Addressing these challenges requires…
Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…
This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…