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Retinal Cysts are formed by leakage and accumulation of fluid in the retina due to the incompetence of retinal vasculature. These cystic spaces have significance in several ocular diseases such as age-related macular degeneration, diabetic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Abhishek Dharmaratnakar , Aadheeshwar Vijayakumar , Suchand Dayanand

3D imaging modalities are becoming increasingly popular and relevant in retinal imaging owing to their effectiveness in highlighting structures in sub-retinal layers. OCT is one such modality which has great importance in the context of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-09 Karthik Gopinath , Jayanthi Sivaswamy

Worldwide, sight loss is commonly occurred by retinal diseases, with age-related macular degeneration (AMD) being a notable facet that affects elderly patients. Approaching 170 million persons wide-ranging have been spotted with AMD, a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Khaled Al-Saih , Fares Al-Shargie , Mohammed Isam Al-hiyali , Reham Alhejaili

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. Due to the underlying physics, OCT images usually suffer from a granular…

Computer Vision and Pattern Recognition · Computer Science 2015-02-10 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Optical tomographic cross-sectional images of biological samples were made possible by interferometric imaging techniques such as Optical Coherence Tomography (OCT). Owing to its unprecedented view of the sample, OCT has become a gold…

Medical Physics · Physics 2020-07-13 Pedro Mecê , Elena Gofas-Salas , Michel Paques , Kate Grieve , Serge Meimon

Glaucoma is one of the leading causes of blindness worldwide and Optical Coherence Tomography (OCT) is the quintessential imaging technique for its detection. Unlike most of the state-of-the-art studies focused on glaucoma detection, in…

Image and Video Processing · Electrical Eng. & Systems 2021-06-28 Gabriel García , Rocío del Amor , Adrián Colomer , Rafael Verdú-Monedero , Juan Morales-Sánchez , Valery Naranjo

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

In this paper we present a new method for cystoid macular edema (CME) segmentation in retinal Optical Coherence Tomography (OCT) images, using a fully convolutional neural network (FCN) and a fully connected conditional random fields (dense…

Computer Vision and Pattern Recognition · Computer Science 2017-09-18 Fangliang Bai , Manuel J. Marques , Stuart J. Gibson

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly…

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. In vivo OCT offers rapid, non-invasive imaging but can suffer from clarity issues and motion artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

Artificial intelligence (AI) classification holds promise as a novel and affordable screening tool for clinical management of ocular diseases. Rural and underserved areas, which suffer from lack of access to experienced ophthalmologists may…

Quantitative Methods · Quantitative Biology 2019-06-19 Minhaj Alam , David Le , Jennifer I. Lim , R. V. P. Chan , Xincheng Yao

With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Computer Vision and Pattern Recognition · Computer Science 2015-08-06 Yankui Sun , Tian Zhang , Yue Zhao , Yufan He

Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Omini Rathore , Richard Paul , Abigail Morrison , Hanno Scharr , Elisabeth Pfaehler

The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. (1) The…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Huihong Zhang , Jianlong Yang , Kang Zhou , Fei Li , Yan Hu , Yitian Zhao , Ce Zheng , Xiulan Zhang , Jiang Liu

Optical Coherence Tomography Angiography (OCT-A) is a non-invasive imaging technique, and has been increasingly used to image the retinal vasculature at capillary level resolution. However, automated segmentation of retinal vessels in OCT-A…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Yuhui Ma , Huaying Hao , Huazhu Fu , Jiong Zhang , Jianlong Yang , Jiang Liu , Yalin Zheng , Yitian Zhao

Diabetic Retinopathy (DR) caused by diabetes occurs as a result of changes in the retinal vessels and causes visual impairment. Microaneurysms (MAs) are the early clinical signs of DR, whose timely diagnosis can help detecting DR in the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Elahe Sadat Kazemi Nasab , Ramin Almasi , Bijan Shoushtarian , Ehsan Golkar , Hossein Rabbani